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Title: SU-G-201-07: Dosimetric Verification of a 3D Printed HDR Skin Brachytherapy Applicator

Abstract

Purpose: The use of radiation as a treatment modality for skin cancer has increased significantly over the last decade with standardized applicators. Utilizing 3D printing, the ability to make applicators specifically designed for each patient’s anatomy has become economically feasible. With this in mind it was the aim of this study to determine the dosimetric accuracy of a 3-D printed HDR brachytherapy applicator for the skin. Methods: A CT reference image was used to generate a custom applicator based on an anthropomorphic head and neck phantom. To create the applicator a 1cm expansion anteriorly with 0.5cmX0.5cm trenches on the outer surface that were spaced 1cm sup-inf to accommodate standard 6F flexible catheters. The applicator was printed using PLA material using a printrbot simple printer. A treatment plan optimized to deliver a clinically representative volume was created in Oncentra and delivered with a nucletron afterloader. Measurements were made using TLDs and EBT3 gafchromic film that were placed between the applicator and the phantom’s forehead. An additional piece of film was also used to qualitatively asses the dose distribution in the transverse plane. Using a standard vaginal cylinder and bolus, a standardized curve correlating TLD and film exposure-to-radiation dose was established bymore » irradiating film to known doses (200,500,700 cGy) at a 3.5 cm radius distance. Results: Evaluated TLDs showed the absolute dose delivered to the skin surface using the 3-D printed bolus was 615cGy±6%, with a mean predicted TPS value in the measured area of 617.5±7%. Additionally, planar dose distributions had good qualitative agreement with calculated TPS isodoses. Conclusion: This work demonstrates patient specific 3-D printed HDR brachytherapy applicators for skin cancer treatments are practical and accurate in TPS calculations but additional measurements are needed to verify additional sites and dose at depth.« less

Authors:
; ; ; ; ; ;  [1]; ; ; ; ; ;  [2];  [3]
  1. University of Texas HSC SA, San Antonio, TX (United States)
  2. East Carolina University, Greenville, NC (United States)
  3. Greenville Health System, Greenville, SC (United States)
Publication Date:
OSTI Identifier:
22649249
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 43; Journal Issue: 6; Other Information: (c) 2016 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 61 RADIATION PROTECTION AND DOSIMETRY; BRACHYTHERAPY; DOSIMETRY; RADIATION DOSE DISTRIBUTIONS; SKIN

Citation Formats

Rasmussen, K, Stanley, D, Eng, T, Kirby, N, Gutierrez, A, Stathakis, S, Papanikolaou, N, Baumgarten, A, Pelletier, C, Jung, J, Feng, Y, Huang, Z, Ju, A, and Corbett, M. SU-G-201-07: Dosimetric Verification of a 3D Printed HDR Skin Brachytherapy Applicator. United States: N. p., 2016. Web. doi:10.1118/1.4956880.
Rasmussen, K, Stanley, D, Eng, T, Kirby, N, Gutierrez, A, Stathakis, S, Papanikolaou, N, Baumgarten, A, Pelletier, C, Jung, J, Feng, Y, Huang, Z, Ju, A, & Corbett, M. SU-G-201-07: Dosimetric Verification of a 3D Printed HDR Skin Brachytherapy Applicator. United States. doi:10.1118/1.4956880.
Rasmussen, K, Stanley, D, Eng, T, Kirby, N, Gutierrez, A, Stathakis, S, Papanikolaou, N, Baumgarten, A, Pelletier, C, Jung, J, Feng, Y, Huang, Z, Ju, A, and Corbett, M. Wed . "SU-G-201-07: Dosimetric Verification of a 3D Printed HDR Skin Brachytherapy Applicator". United States. doi:10.1118/1.4956880.
@article{osti_22649249,
title = {SU-G-201-07: Dosimetric Verification of a 3D Printed HDR Skin Brachytherapy Applicator},
author = {Rasmussen, K and Stanley, D and Eng, T and Kirby, N and Gutierrez, A and Stathakis, S and Papanikolaou, N and Baumgarten, A and Pelletier, C and Jung, J and Feng, Y and Huang, Z and Ju, A and Corbett, M},
abstractNote = {Purpose: The use of radiation as a treatment modality for skin cancer has increased significantly over the last decade with standardized applicators. Utilizing 3D printing, the ability to make applicators specifically designed for each patient’s anatomy has become economically feasible. With this in mind it was the aim of this study to determine the dosimetric accuracy of a 3-D printed HDR brachytherapy applicator for the skin. Methods: A CT reference image was used to generate a custom applicator based on an anthropomorphic head and neck phantom. To create the applicator a 1cm expansion anteriorly with 0.5cmX0.5cm trenches on the outer surface that were spaced 1cm sup-inf to accommodate standard 6F flexible catheters. The applicator was printed using PLA material using a printrbot simple printer. A treatment plan optimized to deliver a clinically representative volume was created in Oncentra and delivered with a nucletron afterloader. Measurements were made using TLDs and EBT3 gafchromic film that were placed between the applicator and the phantom’s forehead. An additional piece of film was also used to qualitatively asses the dose distribution in the transverse plane. Using a standard vaginal cylinder and bolus, a standardized curve correlating TLD and film exposure-to-radiation dose was established by irradiating film to known doses (200,500,700 cGy) at a 3.5 cm radius distance. Results: Evaluated TLDs showed the absolute dose delivered to the skin surface using the 3-D printed bolus was 615cGy±6%, with a mean predicted TPS value in the measured area of 617.5±7%. Additionally, planar dose distributions had good qualitative agreement with calculated TPS isodoses. Conclusion: This work demonstrates patient specific 3-D printed HDR brachytherapy applicators for skin cancer treatments are practical and accurate in TPS calculations but additional measurements are needed to verify additional sites and dose at depth.},
doi = {10.1118/1.4956880},
journal = {Medical Physics},
number = 6,
volume = 43,
place = {United States},
year = {Wed Jun 15 00:00:00 EDT 2016},
month = {Wed Jun 15 00:00:00 EDT 2016}
}