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Title: SU-F-T-549: Validation of a Method for in Vivo 3D Dose Reconstruction for SBRT Using a New Transmission Detector

Abstract

Purpose: Recently, there has been increased clinical use of stereotactic body radiation therapy (SBRT). SBRT treatments will strongly benefit from in vivo patient dose verification, as any errors in delivery can be more detrimental to the radiobiology of the patient as compared to conventional therapy. In vivo dose measurements, a commercially available quality assurance platform which is able to correlate the delivered dose to the patient’s anatomy and take into account tissue inhomogeneity, is the COMPASS system (IBA Dosimetry, Germany) using a new transmission detector (Dolphin, IBA Dosimetry). In this work, we evaluate a method for in vivo 3D dose reconstruction for SBRT using a new transmission detector, which was developed for in vivo dose verification for intensity-modulated radiation therapy (IMRT). Methods: We evaluated the accuracy of measurement for SBRT using simple small fields (2×2−10×10 cm2), a multileaf collimator (MLC) test pattern, and clinical cases. The dose distributions from the COMPASS were compared with those of EDR2 films (Kodak, USA) and the Monte Carlo simulations (MC). For clinical cases, we compared MC using dose-volume-histograms (DVHs) and dose profiles. Results: The dose profiles from the COMPASS for small fields and the complicated MLC test pattern agreed with those of EDR2 films,more » and MC within 3%. This showed the COMPASS with Dolphin system showed good spatial resolution and can measure small fields which are required for SBRT. Those results also suggest that COMPASS with Dolphin is able to detect MLC leaf position errors for SBRT. In clinical cases, the COMPASS with Dolphin agreed well with MC. The Dolphin detector, which consists of ionization chambers, provided stable measurement. Conclusion: COMPASS with Dolphin detector showed a useful in vivo 3D dose reconstruction for SBRT. The accuracy of the results indicates that this approach is suitable for clinical implementation.« less

Authors:
; ; ;  [1]
  1. Kumamoto University Hospital, Kumamoto, Kumamoto (Japan)
Publication Date:
OSTI Identifier:
22649125
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 43; Journal Issue: 6; Other Information: (c) 2016 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 61 RADIATION PROTECTION AND DOSIMETRY; CETACEANS; COMPUTERIZED SIMULATION; IONIZATION CHAMBERS; MONTE CARLO METHOD; PATIENTS; QUALITY ASSURANCE; RADIATION DOSE DISTRIBUTIONS; RADIOTHERAPY; SPATIAL RESOLUTION; TRANSMISSION

Citation Formats

Nakaguchi, Y, Shimohigashi, Y, Onizuka, R, and Ohno, T. SU-F-T-549: Validation of a Method for in Vivo 3D Dose Reconstruction for SBRT Using a New Transmission Detector. United States: N. p., 2016. Web. doi:10.1118/1.4956734.
Nakaguchi, Y, Shimohigashi, Y, Onizuka, R, & Ohno, T. SU-F-T-549: Validation of a Method for in Vivo 3D Dose Reconstruction for SBRT Using a New Transmission Detector. United States. doi:10.1118/1.4956734.
Nakaguchi, Y, Shimohigashi, Y, Onizuka, R, and Ohno, T. Wed . "SU-F-T-549: Validation of a Method for in Vivo 3D Dose Reconstruction for SBRT Using a New Transmission Detector". United States. doi:10.1118/1.4956734.
@article{osti_22649125,
title = {SU-F-T-549: Validation of a Method for in Vivo 3D Dose Reconstruction for SBRT Using a New Transmission Detector},
author = {Nakaguchi, Y and Shimohigashi, Y and Onizuka, R and Ohno, T},
abstractNote = {Purpose: Recently, there has been increased clinical use of stereotactic body radiation therapy (SBRT). SBRT treatments will strongly benefit from in vivo patient dose verification, as any errors in delivery can be more detrimental to the radiobiology of the patient as compared to conventional therapy. In vivo dose measurements, a commercially available quality assurance platform which is able to correlate the delivered dose to the patient’s anatomy and take into account tissue inhomogeneity, is the COMPASS system (IBA Dosimetry, Germany) using a new transmission detector (Dolphin, IBA Dosimetry). In this work, we evaluate a method for in vivo 3D dose reconstruction for SBRT using a new transmission detector, which was developed for in vivo dose verification for intensity-modulated radiation therapy (IMRT). Methods: We evaluated the accuracy of measurement for SBRT using simple small fields (2×2−10×10 cm2), a multileaf collimator (MLC) test pattern, and clinical cases. The dose distributions from the COMPASS were compared with those of EDR2 films (Kodak, USA) and the Monte Carlo simulations (MC). For clinical cases, we compared MC using dose-volume-histograms (DVHs) and dose profiles. Results: The dose profiles from the COMPASS for small fields and the complicated MLC test pattern agreed with those of EDR2 films, and MC within 3%. This showed the COMPASS with Dolphin system showed good spatial resolution and can measure small fields which are required for SBRT. Those results also suggest that COMPASS with Dolphin is able to detect MLC leaf position errors for SBRT. In clinical cases, the COMPASS with Dolphin agreed well with MC. The Dolphin detector, which consists of ionization chambers, provided stable measurement. Conclusion: COMPASS with Dolphin detector showed a useful in vivo 3D dose reconstruction for SBRT. The accuracy of the results indicates that this approach is suitable for clinical implementation.},
doi = {10.1118/1.4956734},
journal = {Medical Physics},
number = 6,
volume = 43,
place = {United States},
year = {Wed Jun 15 00:00:00 EDT 2016},
month = {Wed Jun 15 00:00:00 EDT 2016}
}