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Title: Diffusion-Weighted MRI Assessment of Adjacent Disc Degeneration After Thoracolumbar Vertebral Fractures

Abstract

ObjectiveThe purpose of this study was to assess, by the mean apparent diffusion coefficient (ADC), if a relationship exists between disc ADC and MR findings of adjacent disc degeneration after thoracolumbar fractures treated by anatomic reduction using vertebral augmentation (VAP).Materials and MethodsTwenty non-consecutive patients (mean age 50.7 years; range 45–56) treated because of vertebral fractures, were included in this study. There were 10 A3.1 and 10 A1.2 fractures (AO classification). Surgical treatment using VAP was applied in 14 cases, and conservative in 6 patients. MRI T2-weighted images and mapping of apparent diffusion coefficient (ADC) of the intervertebral disc adjacent to the fractured segment were performed after a mean follow-up of 32 months. A total of 60 discs, 3 per patient, were analysed: infra-adjacent, supra-adjacent and a control disc one level above the supra-adjacent.ResultsNo differences between patients surgically treated and those following a conservative protocol regarding the average ADC values obtained in the 20 control discs analysed were found. Considering all discs, average ADC in the supra-adjacent level was lower than in the infra-adjacent (1.35 ± 0.12 vs. 1.53 ± 0.06; p < 0.001). Average ADC values of the discs used as a control were similar to those of the infra-adjacent level (1.54 ± 0.06). Compared to surgically treated patients, discsmore » at the supra-adjacent fracture level showed statistically significant lower values in cases treated conservatively (p < 0.001). The variation in the delay of surgery had no influence on the average values of ADC at any of the measured levels.ConclusionsADC measurements of the supra-adjacent discs after a mean follow-up of 32 months following thoracolumbar fractures, showed that restoration of the vertebral collapse by minimally invasive VAP prevents posttraumatic disc degeneration.« less

Authors:
 [1];  [2];  [1];  [3];  [4];  [5]
  1. Valladolid University Hospital, Spine Department (Spain)
  2. SS. Trinità Hospital ASL 8 Cagliari, Department of Radiology (Italy)
  3. Valladolid University Hospital, Radiology Department (Spain)
  4. Azienda Ospedaliero Brotzu (A.O.B.), Department of Radiology (Italy)
  5. Azienda Ospedaliero Universitaria (A.O.U.), Department of Radiology (Italy)
Publication Date:
OSTI Identifier:
22645459
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cardiovascular and Interventional Radiology; Journal Volume: 39; Journal Issue: 9; Other Information: Copyright (c) 2016 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CLASSIFICATION; DIFFUSION; IMAGES; NMR IMAGING; PATIENTS; SURGERY; VASCULAR DISEASES

Citation Formats

Noriega, David C., E-mail: dcnoriega1970@gmail.com, Marcia, Stefano, E-mail: stemarcia@gmail.com, Ardura, Francisco, E-mail: fardura@ono.com, Lite, Israel Sanchez, E-mail: israelslite@hotmail.com, Marras, Mariangela, E-mail: mariangela.marrasmd@gmail.com, and Saba, Luca, E-mail: lucasaba@tiscali.it. Diffusion-Weighted MRI Assessment of Adjacent Disc Degeneration After Thoracolumbar Vertebral Fractures. United States: N. p., 2016. Web. doi:10.1007/S00270-016-1369-3.
Noriega, David C., E-mail: dcnoriega1970@gmail.com, Marcia, Stefano, E-mail: stemarcia@gmail.com, Ardura, Francisco, E-mail: fardura@ono.com, Lite, Israel Sanchez, E-mail: israelslite@hotmail.com, Marras, Mariangela, E-mail: mariangela.marrasmd@gmail.com, & Saba, Luca, E-mail: lucasaba@tiscali.it. Diffusion-Weighted MRI Assessment of Adjacent Disc Degeneration After Thoracolumbar Vertebral Fractures. United States. doi:10.1007/S00270-016-1369-3.
Noriega, David C., E-mail: dcnoriega1970@gmail.com, Marcia, Stefano, E-mail: stemarcia@gmail.com, Ardura, Francisco, E-mail: fardura@ono.com, Lite, Israel Sanchez, E-mail: israelslite@hotmail.com, Marras, Mariangela, E-mail: mariangela.marrasmd@gmail.com, and Saba, Luca, E-mail: lucasaba@tiscali.it. Thu . "Diffusion-Weighted MRI Assessment of Adjacent Disc Degeneration After Thoracolumbar Vertebral Fractures". United States. doi:10.1007/S00270-016-1369-3.
@article{osti_22645459,
title = {Diffusion-Weighted MRI Assessment of Adjacent Disc Degeneration After Thoracolumbar Vertebral Fractures},
author = {Noriega, David C., E-mail: dcnoriega1970@gmail.com and Marcia, Stefano, E-mail: stemarcia@gmail.com and Ardura, Francisco, E-mail: fardura@ono.com and Lite, Israel Sanchez, E-mail: israelslite@hotmail.com and Marras, Mariangela, E-mail: mariangela.marrasmd@gmail.com and Saba, Luca, E-mail: lucasaba@tiscali.it},
abstractNote = {ObjectiveThe purpose of this study was to assess, by the mean apparent diffusion coefficient (ADC), if a relationship exists between disc ADC and MR findings of adjacent disc degeneration after thoracolumbar fractures treated by anatomic reduction using vertebral augmentation (VAP).Materials and MethodsTwenty non-consecutive patients (mean age 50.7 years; range 45–56) treated because of vertebral fractures, were included in this study. There were 10 A3.1 and 10 A1.2 fractures (AO classification). Surgical treatment using VAP was applied in 14 cases, and conservative in 6 patients. MRI T2-weighted images and mapping of apparent diffusion coefficient (ADC) of the intervertebral disc adjacent to the fractured segment were performed after a mean follow-up of 32 months. A total of 60 discs, 3 per patient, were analysed: infra-adjacent, supra-adjacent and a control disc one level above the supra-adjacent.ResultsNo differences between patients surgically treated and those following a conservative protocol regarding the average ADC values obtained in the 20 control discs analysed were found. Considering all discs, average ADC in the supra-adjacent level was lower than in the infra-adjacent (1.35 ± 0.12 vs. 1.53 ± 0.06; p < 0.001). Average ADC values of the discs used as a control were similar to those of the infra-adjacent level (1.54 ± 0.06). Compared to surgically treated patients, discs at the supra-adjacent fracture level showed statistically significant lower values in cases treated conservatively (p < 0.001). The variation in the delay of surgery had no influence on the average values of ADC at any of the measured levels.ConclusionsADC measurements of the supra-adjacent discs after a mean follow-up of 32 months following thoracolumbar fractures, showed that restoration of the vertebral collapse by minimally invasive VAP prevents posttraumatic disc degeneration.},
doi = {10.1007/S00270-016-1369-3},
journal = {Cardiovascular and Interventional Radiology},
number = 9,
volume = 39,
place = {United States},
year = {Thu Sep 15 00:00:00 EDT 2016},
month = {Thu Sep 15 00:00:00 EDT 2016}
}