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Title: A Single-Institution Experience in Percutaneous Image-Guided Biopsy of Malignant Pleural Mesothelioma

Abstract

PurposeMesothelioma has been considered a difficult pathologic diagnosis to achieve via image-guided core needle biopsy. The purpose of this study was to assess the diagnostic sensitivity of percutaneous image-guided biopsy for diagnosis of pleural mesothelioma.Materials and MethodsRetrospective review was performed to identify patients with a confirmed diagnosis of pleural mesothelioma and who underwent image-guided needle biopsy between January 1, 2002, and January 1, 2016. Thirty-two patients with pleural mesothelioma were identified and included for analysis in 33 image-guided biopsy procedures. Patient, procedural, and pathologic characteristics were recorded. Complications were characterized via standardized nomenclature [Common Terminology for Clinically Adverse Events (CTCAE)].ResultsPercutaneous image-guided biopsy was associated with an overall sensitivity of 81%. No CTCAE clinically significant complications were observed. No image-guided procedures were complicated by pneumothorax or necessitated chest tube placement. No patients had tumor seeding of the biopsy tract.ConclusionPercutaneous image-guided biopsy can achieve high sensitivity for pathologic diagnosis of pleural mesothelioma with a low procedural complication rate, potentially obviating need for surgical biopsy.

Authors:
; ;  [1];  [2];  [3];  [4];  [1]
  1. Mayo Clinic, Department of Radiology (United States)
  2. Mayo Clinic, Department of Pulmonary and Critical Care Medicine (United States)
  3. Mayo Clinic, Department of Pathology (United States)
  4. Mayo Clinic, Department of Thoracic Surgery (United States)
Publication Date:
OSTI Identifier:
22645176
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cardiovascular and Interventional Radiology; Journal Volume: 40; Journal Issue: 6; Other Information: Copyright (c) 2017 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BIOPSY; CHEST; DIAGNOSIS; IMAGES; NEOPLASMS; PATIENTS; REVIEWS; SENSITIVITY; SURGERY; VASCULAR DISEASES

Citation Formats

Welch, B. T., E-mail: Welch.brian@mayo.edu, Eiken, P. W., Atwell, T. D., Peikert, T., Yi, E. S., Nichols, F., and Schmit, G. D.. A Single-Institution Experience in Percutaneous Image-Guided Biopsy of Malignant Pleural Mesothelioma. United States: N. p., 2017. Web. doi:10.1007/S00270-017-1583-7.
Welch, B. T., E-mail: Welch.brian@mayo.edu, Eiken, P. W., Atwell, T. D., Peikert, T., Yi, E. S., Nichols, F., & Schmit, G. D.. A Single-Institution Experience in Percutaneous Image-Guided Biopsy of Malignant Pleural Mesothelioma. United States. doi:10.1007/S00270-017-1583-7.
Welch, B. T., E-mail: Welch.brian@mayo.edu, Eiken, P. W., Atwell, T. D., Peikert, T., Yi, E. S., Nichols, F., and Schmit, G. D.. Thu . "A Single-Institution Experience in Percutaneous Image-Guided Biopsy of Malignant Pleural Mesothelioma". United States. doi:10.1007/S00270-017-1583-7.
@article{osti_22645176,
title = {A Single-Institution Experience in Percutaneous Image-Guided Biopsy of Malignant Pleural Mesothelioma},
author = {Welch, B. T., E-mail: Welch.brian@mayo.edu and Eiken, P. W. and Atwell, T. D. and Peikert, T. and Yi, E. S. and Nichols, F. and Schmit, G. D.},
abstractNote = {PurposeMesothelioma has been considered a difficult pathologic diagnosis to achieve via image-guided core needle biopsy. The purpose of this study was to assess the diagnostic sensitivity of percutaneous image-guided biopsy for diagnosis of pleural mesothelioma.Materials and MethodsRetrospective review was performed to identify patients with a confirmed diagnosis of pleural mesothelioma and who underwent image-guided needle biopsy between January 1, 2002, and January 1, 2016. Thirty-two patients with pleural mesothelioma were identified and included for analysis in 33 image-guided biopsy procedures. Patient, procedural, and pathologic characteristics were recorded. Complications were characterized via standardized nomenclature [Common Terminology for Clinically Adverse Events (CTCAE)].ResultsPercutaneous image-guided biopsy was associated with an overall sensitivity of 81%. No CTCAE clinically significant complications were observed. No image-guided procedures were complicated by pneumothorax or necessitated chest tube placement. No patients had tumor seeding of the biopsy tract.ConclusionPercutaneous image-guided biopsy can achieve high sensitivity for pathologic diagnosis of pleural mesothelioma with a low procedural complication rate, potentially obviating need for surgical biopsy.},
doi = {10.1007/S00270-017-1583-7},
journal = {Cardiovascular and Interventional Radiology},
number = 6,
volume = 40,
place = {United States},
year = {Thu Jun 15 00:00:00 EDT 2017},
month = {Thu Jun 15 00:00:00 EDT 2017}
}