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Title: Development and Evaluation of a Novel Curved Biopsy Device for CT-Guided Biopsy of Lesions Unreachable Using Standard Straight Needle Trajectories

Abstract

PurposeTo evaluate the feasibility of a novel curved CT-guided biopsy needle prototype with shape memory to access otherwise not accessible biopsy targets.Methods and MaterialsA biopsy needle curved by 90° with specific radius was designed. It was manufactured using nitinol to acquire shape memory, encased in a straight guiding trocar to be driven out for access of otherwise inaccessible targets. Fifty CT-guided punctures were conducted in a biopsy phantom and 10 CT-guided punctures in a swine corpse. Biposies from porcine liver and muscle tissue were separately gained using the biopsy device, and histological examination was performed subsequently.ResultsMean time for placement of the trocar and deployment of the inner biopsy needle was ~205 ± 69 and ~93 ± 58 s, respectively, with a mean of ~4.5 ± 1.3 steps to reach adequate biopsy position. Mean distance from the tip of the needle to the target was ~0.7 ± 0.8 mm. CT-guided punctures in the swine corpse took relatively longer and required more biopsy steps (~574 ± 107 and ~380 ± 148 s, 8 ± 2.6 steps). Histology demonstrated appropriate tissue samples in nine out of ten cases (90%).ConclusionsTargets that were otherwise inaccessible via standard straight needle trajectories could be successfully reached with the curved biopsy needle prototype. Shape memory and preformed size with specific radius of the curvedmore » needle simplify the target accessibility with a low risk of injuring adjacent structures.« less

Authors:
; ; ;  [1];  [2]; ; ;  [1]
  1. University Hospital RWTH Aachen, Department of Diagnostic and Interventional Radiology (Germany)
  2. University Hospital RWTH Aachen, Department of Pathology (Germany)
Publication Date:
OSTI Identifier:
22645169
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cardiovascular and Interventional Radiology; Journal Volume: 40; Journal Issue: 6; Other Information: Copyright (c) 2017 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ANIMAL TISSUES; BIOPSY; COMPUTERIZED TOMOGRAPHY; HAZARDS; HISTOLOGY; LIVER; MUSCLES; NICKEL ALLOYS; PHANTOMS; SHAPE MEMORY EFFECT; SWINE; TITANIUM ALLOYS

Citation Formats

Schulze-Hagen, Maximilian Franz, E-mail: mschulze@ukaachen.de, Pfeffer, Jochen, Zimmermann, Markus, Liebl, Martin, Stillfried, Saskia Freifrau von, Kuhl, Christiane, Bruners, Philipp, and Isfort, Peter. Development and Evaluation of a Novel Curved Biopsy Device for CT-Guided Biopsy of Lesions Unreachable Using Standard Straight Needle Trajectories. United States: N. p., 2017. Web. doi:10.1007/S00270-017-1597-1.
Schulze-Hagen, Maximilian Franz, E-mail: mschulze@ukaachen.de, Pfeffer, Jochen, Zimmermann, Markus, Liebl, Martin, Stillfried, Saskia Freifrau von, Kuhl, Christiane, Bruners, Philipp, & Isfort, Peter. Development and Evaluation of a Novel Curved Biopsy Device for CT-Guided Biopsy of Lesions Unreachable Using Standard Straight Needle Trajectories. United States. doi:10.1007/S00270-017-1597-1.
Schulze-Hagen, Maximilian Franz, E-mail: mschulze@ukaachen.de, Pfeffer, Jochen, Zimmermann, Markus, Liebl, Martin, Stillfried, Saskia Freifrau von, Kuhl, Christiane, Bruners, Philipp, and Isfort, Peter. Thu . "Development and Evaluation of a Novel Curved Biopsy Device for CT-Guided Biopsy of Lesions Unreachable Using Standard Straight Needle Trajectories". United States. doi:10.1007/S00270-017-1597-1.
@article{osti_22645169,
title = {Development and Evaluation of a Novel Curved Biopsy Device for CT-Guided Biopsy of Lesions Unreachable Using Standard Straight Needle Trajectories},
author = {Schulze-Hagen, Maximilian Franz, E-mail: mschulze@ukaachen.de and Pfeffer, Jochen and Zimmermann, Markus and Liebl, Martin and Stillfried, Saskia Freifrau von and Kuhl, Christiane and Bruners, Philipp and Isfort, Peter},
abstractNote = {PurposeTo evaluate the feasibility of a novel curved CT-guided biopsy needle prototype with shape memory to access otherwise not accessible biopsy targets.Methods and MaterialsA biopsy needle curved by 90° with specific radius was designed. It was manufactured using nitinol to acquire shape memory, encased in a straight guiding trocar to be driven out for access of otherwise inaccessible targets. Fifty CT-guided punctures were conducted in a biopsy phantom and 10 CT-guided punctures in a swine corpse. Biposies from porcine liver and muscle tissue were separately gained using the biopsy device, and histological examination was performed subsequently.ResultsMean time for placement of the trocar and deployment of the inner biopsy needle was ~205 ± 69 and ~93 ± 58 s, respectively, with a mean of ~4.5 ± 1.3 steps to reach adequate biopsy position. Mean distance from the tip of the needle to the target was ~0.7 ± 0.8 mm. CT-guided punctures in the swine corpse took relatively longer and required more biopsy steps (~574 ± 107 and ~380 ± 148 s, 8 ± 2.6 steps). Histology demonstrated appropriate tissue samples in nine out of ten cases (90%).ConclusionsTargets that were otherwise inaccessible via standard straight needle trajectories could be successfully reached with the curved biopsy needle prototype. Shape memory and preformed size with specific radius of the curved needle simplify the target accessibility with a low risk of injuring adjacent structures.},
doi = {10.1007/S00270-017-1597-1},
journal = {Cardiovascular and Interventional Radiology},
number = 6,
volume = 40,
place = {United States},
year = {Thu Jun 15 00:00:00 EDT 2017},
month = {Thu Jun 15 00:00:00 EDT 2017}
}