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Title: Radioembolization: Is Prophylactic Embolization of Hepaticoenteric Arteries Necessary? A Systematic Review

Abstract

PurposeTo study the effectiveness of prophylactic embolization of hepaticoenteric arteries to prevent gastrointestinal complications during radioembolization.MethodsA PubMed, Embase and Cochrane literature search was performed. We included studies assessing both a group of patients with and without embolization.ResultsOur search revealed 1401 articles of which title and abstract were screened. Finally, eight studies were included investigating 1237 patients. Of these patients, 456 received embolization of one or more arteries. No difference was seen in the incidence of gastrointestinal complications in patients with prophylactic embolization of the gastroduodenal artery (GDA), right gastric artery (RGA), cystic artery (CA) or hepatic falciform artery (HFA) compared to patients without embolization. Few complications were reported when microspheres were injected distal to the origin of these arteries or when reversed flow of the GDA was present. A high risk of confounding by indication was present because of the non-randomized nature of the included studies.ConclusionIt is advisable to restrict embolization to those hepaticoenteric arteries that originate distally or close to the injection site of microspheres. There is no conclusive evidence that embolization of hepaticoenteric arteries influences the risk of complications.

Authors:
; ; ; ;  [1];  [2];  [1]
  1. University Medical Center Utrecht, Division of Radiology and Nuclear Medicine (Netherlands)
  2. University Medical Center Utrecht, Julius Center for Health Sciences and Primary Care (Netherlands)
Publication Date:
OSTI Identifier:
22642522
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cardiovascular and Interventional Radiology; Journal Volume: 39; Journal Issue: 5; Other Information: Copyright (c) 2016 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); Article Copyright (c) 2016 The Author(s); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ARTERIES; GADOLINIUM ARSENIDES; HAZARDS; LIVER; MICROSPHERES; PATIENTS; RADIOEMBOLIZATION; REVIEWS; VASCULAR DISEASES

Citation Formats

Borggreve, Alicia S., E-mail: alicia.borggreve@gmail.com, Landman, Anadeijda J. E. M. C., E-mail: ajemclandman@gmail.com, Vissers, Coco M. J., E-mail: coco.vissers@hotmail.com, De Jong, Charlotte D., E-mail: charlotte-dejong@live.nl, Lam, Marnix G. E. H., E-mail: m.lam@umcutrecht.nl, Monninkhof, Evelyn M., E-mail: e.monninkhof@umcutrecht.nl, and Prince, Jip F., E-mail: jipfprince@gmail.com. Radioembolization: Is Prophylactic Embolization of Hepaticoenteric Arteries Necessary? A Systematic Review. United States: N. p., 2016. Web. doi:10.1007/S00270-016-1310-9.
Borggreve, Alicia S., E-mail: alicia.borggreve@gmail.com, Landman, Anadeijda J. E. M. C., E-mail: ajemclandman@gmail.com, Vissers, Coco M. J., E-mail: coco.vissers@hotmail.com, De Jong, Charlotte D., E-mail: charlotte-dejong@live.nl, Lam, Marnix G. E. H., E-mail: m.lam@umcutrecht.nl, Monninkhof, Evelyn M., E-mail: e.monninkhof@umcutrecht.nl, & Prince, Jip F., E-mail: jipfprince@gmail.com. Radioembolization: Is Prophylactic Embolization of Hepaticoenteric Arteries Necessary? A Systematic Review. United States. doi:10.1007/S00270-016-1310-9.
Borggreve, Alicia S., E-mail: alicia.borggreve@gmail.com, Landman, Anadeijda J. E. M. C., E-mail: ajemclandman@gmail.com, Vissers, Coco M. J., E-mail: coco.vissers@hotmail.com, De Jong, Charlotte D., E-mail: charlotte-dejong@live.nl, Lam, Marnix G. E. H., E-mail: m.lam@umcutrecht.nl, Monninkhof, Evelyn M., E-mail: e.monninkhof@umcutrecht.nl, and Prince, Jip F., E-mail: jipfprince@gmail.com. Sun . "Radioembolization: Is Prophylactic Embolization of Hepaticoenteric Arteries Necessary? A Systematic Review". United States. doi:10.1007/S00270-016-1310-9.
@article{osti_22642522,
title = {Radioembolization: Is Prophylactic Embolization of Hepaticoenteric Arteries Necessary? A Systematic Review},
author = {Borggreve, Alicia S., E-mail: alicia.borggreve@gmail.com and Landman, Anadeijda J. E. M. C., E-mail: ajemclandman@gmail.com and Vissers, Coco M. J., E-mail: coco.vissers@hotmail.com and De Jong, Charlotte D., E-mail: charlotte-dejong@live.nl and Lam, Marnix G. E. H., E-mail: m.lam@umcutrecht.nl and Monninkhof, Evelyn M., E-mail: e.monninkhof@umcutrecht.nl and Prince, Jip F., E-mail: jipfprince@gmail.com},
abstractNote = {PurposeTo study the effectiveness of prophylactic embolization of hepaticoenteric arteries to prevent gastrointestinal complications during radioembolization.MethodsA PubMed, Embase and Cochrane literature search was performed. We included studies assessing both a group of patients with and without embolization.ResultsOur search revealed 1401 articles of which title and abstract were screened. Finally, eight studies were included investigating 1237 patients. Of these patients, 456 received embolization of one or more arteries. No difference was seen in the incidence of gastrointestinal complications in patients with prophylactic embolization of the gastroduodenal artery (GDA), right gastric artery (RGA), cystic artery (CA) or hepatic falciform artery (HFA) compared to patients without embolization. Few complications were reported when microspheres were injected distal to the origin of these arteries or when reversed flow of the GDA was present. A high risk of confounding by indication was present because of the non-randomized nature of the included studies.ConclusionIt is advisable to restrict embolization to those hepaticoenteric arteries that originate distally or close to the injection site of microspheres. There is no conclusive evidence that embolization of hepaticoenteric arteries influences the risk of complications.},
doi = {10.1007/S00270-016-1310-9},
journal = {Cardiovascular and Interventional Radiology},
number = 5,
volume = 39,
place = {United States},
year = {Sun May 15 00:00:00 EDT 2016},
month = {Sun May 15 00:00:00 EDT 2016}
}