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Title: A Pitfall of Cryoadhesional Displacement During Cryoablation of Lung Metastasis to Require Modification of Triple-Freeze Protocol

Abstract

No abstract prepared.

Authors:
;  [1];  [2];  [1];  [3]; ; ;  [1]
  1. University Hospital of Strasbourg, Department of Interventional Radiology (France)
  2. Norfolk and Norwich University Hospital, Department of Radiology (United Kingdom)
  3. University of Strasbourg, ICube (France)
Publication Date:
OSTI Identifier:
22642500
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cardiovascular and Interventional Radiology; Journal Volume: 39; Journal Issue: 6; Other Information: Copyright (c) 2016 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; LUNGS; METASTASES; MODIFICATIONS; THERAPY; VASCULAR DISEASES

Citation Formats

Garnon, Julien, E-mail: juliengarnon@gmail.com, Koch, Guillaume, E-mail: Guillaume.koch@gmail.com, Ramamurthy, Nitin, E-mail: Nitin-ramamurthy@hotmail.com, Caudrelier, Jean, E-mail: caudjean@yahoo.fr, Rao, Pramod, E-mail: pramodrao@me.com, Tsoumakidou, Georgia, E-mail: gtsoumakidou@yahoo.com, Cazzato, Roberto Luigi, E-mail: cazzatorobertoluigi@gmail.com, and Gangi, Afshin, E-mail: gangi@unistra.fr. A Pitfall of Cryoadhesional Displacement During Cryoablation of Lung Metastasis to Require Modification of Triple-Freeze Protocol. United States: N. p., 2016. Web. doi:10.1007/S00270-016-1312-7.
Garnon, Julien, E-mail: juliengarnon@gmail.com, Koch, Guillaume, E-mail: Guillaume.koch@gmail.com, Ramamurthy, Nitin, E-mail: Nitin-ramamurthy@hotmail.com, Caudrelier, Jean, E-mail: caudjean@yahoo.fr, Rao, Pramod, E-mail: pramodrao@me.com, Tsoumakidou, Georgia, E-mail: gtsoumakidou@yahoo.com, Cazzato, Roberto Luigi, E-mail: cazzatorobertoluigi@gmail.com, & Gangi, Afshin, E-mail: gangi@unistra.fr. A Pitfall of Cryoadhesional Displacement During Cryoablation of Lung Metastasis to Require Modification of Triple-Freeze Protocol. United States. doi:10.1007/S00270-016-1312-7.
Garnon, Julien, E-mail: juliengarnon@gmail.com, Koch, Guillaume, E-mail: Guillaume.koch@gmail.com, Ramamurthy, Nitin, E-mail: Nitin-ramamurthy@hotmail.com, Caudrelier, Jean, E-mail: caudjean@yahoo.fr, Rao, Pramod, E-mail: pramodrao@me.com, Tsoumakidou, Georgia, E-mail: gtsoumakidou@yahoo.com, Cazzato, Roberto Luigi, E-mail: cazzatorobertoluigi@gmail.com, and Gangi, Afshin, E-mail: gangi@unistra.fr. 2016. "A Pitfall of Cryoadhesional Displacement During Cryoablation of Lung Metastasis to Require Modification of Triple-Freeze Protocol". United States. doi:10.1007/S00270-016-1312-7.
@article{osti_22642500,
title = {A Pitfall of Cryoadhesional Displacement During Cryoablation of Lung Metastasis to Require Modification of Triple-Freeze Protocol},
author = {Garnon, Julien, E-mail: juliengarnon@gmail.com and Koch, Guillaume, E-mail: Guillaume.koch@gmail.com and Ramamurthy, Nitin, E-mail: Nitin-ramamurthy@hotmail.com and Caudrelier, Jean, E-mail: caudjean@yahoo.fr and Rao, Pramod, E-mail: pramodrao@me.com and Tsoumakidou, Georgia, E-mail: gtsoumakidou@yahoo.com and Cazzato, Roberto Luigi, E-mail: cazzatorobertoluigi@gmail.com and Gangi, Afshin, E-mail: gangi@unistra.fr},
abstractNote = {No abstract prepared.},
doi = {10.1007/S00270-016-1312-7},
journal = {Cardiovascular and Interventional Radiology},
number = 6,
volume = 39,
place = {United States},
year = 2016,
month = 6
}
  • The purpose of this study was to compare a double freeze-thaw protocol to a triple freeze-thaw protocol for pulmonary cryoablation utilizing an in vivo porcine lung model. A total of 18 cryoablations were performed in normal porcine lung utilizing percutaneous technique with 9 each in a double- (10-5-10) and triple-freeze (3-3-7-7-5) protocol. Serial noncontrast CT images were obtained during the ablation. CT imaging findings and pathology were reviewed. No imaging changes were identified during the initial freeze cycle with either protocol. However, during the first thaw cycle, a region of ground glass opacity developed around the probe with both protocols.more » Because the initial freeze was shorter with the triple freeze-thaw protocol, the imaging findings were apparent sooner with this protocol (6 vs. 13 min). Also, despite a shorter total freeze time (15 vs. 20 min), the ablation zone identified with the triple freeze-thaw protocol was not significantly different from the double freeze-thaw protocol (mean diameter: 1.67 {+-} 0.41 cm vs. 1.66 {+-} 0.21 cm, P = 0.77; area: 2.1 {+-} 0.48 cm{sup 2} vs. 1.99 {+-} 0.62 cm{sup 2}, P = 0.7; and circularity: 0.95 {+-} 0.04 vs. 0.96 {+-} 0.03, P = 0.62, respectively). This study suggests that there may be several advantages of a triple freeze-thaw protocol for pulmonary cryoablation, including earlier identification of the imaging findings associated with the ablation, the promise of a shorter procedure time or larger zones of ablation, and theoretically, more effective cytotoxicity related to the additional freeze-thaw cycle.« less
  • IntroductionComputed tomography (CT) fluoroscopy-guided renal cryoablation and lung radiofrequency ablation (RFA) have received increasing attention as promising cancer therapies. Although radiation exposure of interventional radiologists during these procedures is an important concern, data on operator exposure are lacking.Materials and MethodsRadiation dose to interventional radiologists during CT fluoroscopy-guided renal cryoablation (n = 20) and lung RFA (n = 20) was measured prospectively in a clinical setting. Effective dose to the operator was calculated from the 1-cm dose equivalent measured on the neck outside the lead apron, and on the left chest inside the lead apron, using electronic dosimeters. Equivalent dose to the operator’s finger skinmore » was measured using thermoluminescent dosimeter rings.ResultsThe mean (median) effective dose to the operator per procedure was 6.05 (4.52) μSv during renal cryoablation and 0.74 (0.55) μSv during lung RFA. The mean (median) equivalent dose to the operator’s finger skin per procedure was 2.1 (2.1) mSv during renal cryoablation, and 0.3 (0.3) mSv during lung RFA.ConclusionRadiation dose to interventional radiologists during renal cryoablation and lung RFA were at an acceptable level, and in line with recommended dose limits for occupational radiation exposure.« less
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