skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Abscopal Effects and Yttrium-90 Radioembolization

Abstract

We present the case of an 80-year-old male with squamous cell carcinoma with bilobar hepatic metastases who underwent targeted Yttrium-90 radioembolization of the right hepatic lobe lesion. Subsequently, there was complete regression of the nontargeted, left hepatic lobe lesion. This may represent the first ever reported abscopal effect in radioembolization. The abscopal effect refers to the phenomenon of tumor response in nontargeted sites after targeted radiotherapy. In this article, we briefly review the immune-mediated mechanisms responsible for the abscopal effect.

Authors:
;  [1];  [2];  [1]
  1. University Pittsburgh School of Medicine, Department of Radiology (United States)
  2. Emory University School of Medicine, Department of Radiology and Imaging Sciences (United States)
Publication Date:
OSTI Identifier:
22642495
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cardiovascular and Interventional Radiology; Journal Volume: 39; Journal Issue: 7; Other Information: Copyright (c) 2016 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CARCINOMAS; LIVER; MALES; METASTASES; RADIOEMBOLIZATION; REVIEWS; YTTRIUM; YTTRIUM 90

Citation Formats

Ghodadra, Anish, Bhatt, Sumantha, Camacho, Juan C., and Kim, Hyun S., E-mail: kevin.kim@yale.edu. Abscopal Effects and Yttrium-90 Radioembolization. United States: N. p., 2016. Web. doi:10.1007/S00270-015-1259-0.
Ghodadra, Anish, Bhatt, Sumantha, Camacho, Juan C., & Kim, Hyun S., E-mail: kevin.kim@yale.edu. Abscopal Effects and Yttrium-90 Radioembolization. United States. doi:10.1007/S00270-015-1259-0.
Ghodadra, Anish, Bhatt, Sumantha, Camacho, Juan C., and Kim, Hyun S., E-mail: kevin.kim@yale.edu. Fri . "Abscopal Effects and Yttrium-90 Radioembolization". United States. doi:10.1007/S00270-015-1259-0.
@article{osti_22642495,
title = {Abscopal Effects and Yttrium-90 Radioembolization},
author = {Ghodadra, Anish and Bhatt, Sumantha and Camacho, Juan C. and Kim, Hyun S., E-mail: kevin.kim@yale.edu},
abstractNote = {We present the case of an 80-year-old male with squamous cell carcinoma with bilobar hepatic metastases who underwent targeted Yttrium-90 radioembolization of the right hepatic lobe lesion. Subsequently, there was complete regression of the nontargeted, left hepatic lobe lesion. This may represent the first ever reported abscopal effect in radioembolization. The abscopal effect refers to the phenomenon of tumor response in nontargeted sites after targeted radiotherapy. In this article, we briefly review the immune-mediated mechanisms responsible for the abscopal effect.},
doi = {10.1007/S00270-015-1259-0},
journal = {Cardiovascular and Interventional Radiology},
number = 7,
volume = 39,
place = {United States},
year = {Fri Jul 15 00:00:00 EDT 2016},
month = {Fri Jul 15 00:00:00 EDT 2016}
}