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Title: SU-F-J-88: Comparison of Two Deformable Image Registration Algorithms for CT-To-CT Contour Propagation

Abstract

Purpose: To compare the contour propagation accuracy of two deformable image registration (DIR) algorithms in the Raystation treatment planning system – the “Hybrid” algorithm based on image intensities and anatomical information; and the “Biomechanical” algorithm based on linear anatomical elasticity and finite element modeling. Methods: Both DIR algorithms were used for CT-to-CT deformation for 20 lung radiation therapy patients that underwent treatment plan revisions. Deformation accuracy was evaluated using landmark tracking to measure the target registration error (TRE) and inverse consistency error (ICE). The deformed contours were also evaluated against physician drawn contours using Dice similarity coefficients (DSC). Contour propagation was qualitatively assessed using a visual quality score assigned by physicians, and a refinement quality score (0 0.9 for lungs, > 0.85 for heart, > 0.8 for liver) and similar qualitative assessments (VQS < 0.35, RQS > 0.75 for lungs). When anatomical structures were used to control the deformation, the DSC improved more significantly for the biomechanical DIR compared to the hybrid DIR, while the VQS and RQS improved only for the controlling structures. However, while the inclusion of controlling structures improved the TRE for the hybrid DIR, it increased the TRE for the biomechanical DIR. Conclusion: The hybrid DIRmore » was found to perform slightly better than the biomechanical DIR based on lower TRE while the DSC, VQS, and RQS studies yielded comparable results for both. The use of controlling structures showed considerable improvement in the hybrid DIR results and is recommended for clinical use in contour propagation.« less

Authors:
; ;  [1]
  1. University of Maryland School of Medicine, Columbia, MD (United States)
Publication Date:
OSTI Identifier:
22632213
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 43; Journal Issue: 6; Other Information: (c) 2016 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 61 RADIATION PROTECTION AND DOSIMETRY; ACCURACY; ALGORITHMS; CALORIMETRY; COMPARATIVE EVALUATIONS; COMPUTERIZED TOMOGRAPHY; DEFORMATION; ERRORS; FINITE ELEMENT METHOD; HEART; IMAGES; LIVER; LUNGS; PATIENTS; PLANNING; RADIOTHERAPY; SIMULATION

Citation Formats

Gopal, A, Xu, H, and Chen, S. SU-F-J-88: Comparison of Two Deformable Image Registration Algorithms for CT-To-CT Contour Propagation. United States: N. p., 2016. Web. doi:10.1118/1.4955996.
Gopal, A, Xu, H, & Chen, S. SU-F-J-88: Comparison of Two Deformable Image Registration Algorithms for CT-To-CT Contour Propagation. United States. doi:10.1118/1.4955996.
Gopal, A, Xu, H, and Chen, S. Wed . "SU-F-J-88: Comparison of Two Deformable Image Registration Algorithms for CT-To-CT Contour Propagation". United States. doi:10.1118/1.4955996.
@article{osti_22632213,
title = {SU-F-J-88: Comparison of Two Deformable Image Registration Algorithms for CT-To-CT Contour Propagation},
author = {Gopal, A and Xu, H and Chen, S},
abstractNote = {Purpose: To compare the contour propagation accuracy of two deformable image registration (DIR) algorithms in the Raystation treatment planning system – the “Hybrid” algorithm based on image intensities and anatomical information; and the “Biomechanical” algorithm based on linear anatomical elasticity and finite element modeling. Methods: Both DIR algorithms were used for CT-to-CT deformation for 20 lung radiation therapy patients that underwent treatment plan revisions. Deformation accuracy was evaluated using landmark tracking to measure the target registration error (TRE) and inverse consistency error (ICE). The deformed contours were also evaluated against physician drawn contours using Dice similarity coefficients (DSC). Contour propagation was qualitatively assessed using a visual quality score assigned by physicians, and a refinement quality score (0 0.9 for lungs, > 0.85 for heart, > 0.8 for liver) and similar qualitative assessments (VQS < 0.35, RQS > 0.75 for lungs). When anatomical structures were used to control the deformation, the DSC improved more significantly for the biomechanical DIR compared to the hybrid DIR, while the VQS and RQS improved only for the controlling structures. However, while the inclusion of controlling structures improved the TRE for the hybrid DIR, it increased the TRE for the biomechanical DIR. Conclusion: The hybrid DIR was found to perform slightly better than the biomechanical DIR based on lower TRE while the DSC, VQS, and RQS studies yielded comparable results for both. The use of controlling structures showed considerable improvement in the hybrid DIR results and is recommended for clinical use in contour propagation.},
doi = {10.1118/1.4955996},
journal = {Medical Physics},
number = 6,
volume = 43,
place = {United States},
year = {Wed Jun 15 00:00:00 EDT 2016},
month = {Wed Jun 15 00:00:00 EDT 2016}
}