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Title: SU-F-I-14: 3D Breast Digital Phantom for XACT Imaging

Abstract

Purpose: The X-ray induced acoustic computed tomography (XACT) is a new imaging modality which combines X-ray contrast and high ultrasonic resolution in a single modality. Using XACT in breast imaging, a 3D breast volume can be imaged by only one pulsed X-ray radiation, which could dramatically reduce the imaging dose for patients undergoing breast cancer screening and diagnosis. A 3D digital phantom that contains both X-ray properties and acoustic properties of different tissue types is indeed needed for developing and optimizing the XACT system. The purpose of this study is to offer a realistic breast digital phantom as a valuable tool for improving breast XACT imaging techniques and potentially leading to better diagnostic outcomes. Methods: A series of breast CT images along the coronal plane from a patient who has breast calcifications are used as the source images. A HU value based segmentation algorithm is employed to identify breast tissues in five categories, namely the skin tissue, fat tissue, glandular tissue, chest bone and calcifications. For each pixel, the dose related parameters, such as material components and density, and acoustic related parameters, such as frequency-dependent acoustic attenuation coefficient and bandwidth, are assigned based on tissue types. Meanwhile, other parameters whichmore » are used in sound propagation, including the sound speed, thermal expansion coefficient, and heat capacity are also assigned to each tissue. Results: A series of 2D tissue type image is acquired first and the 3D digital breast phantom is obtained by using commercial 3D reconstruction software. When giving specific settings including dose depositions and ultrasound center frequency, the X-ray induced initial pressure rise can be calculated accordingly. Conclusion: The proposed 3D breast digital phantom represents a realistic breast anatomic structure and provides a valuable tool for developing and evaluating the system performance for XACT.« less

Authors:
; ; ; ;  [1]; ;  [2];  [3]
  1. University of Oklahoma, Norman, OK (United States)
  2. University of Oklahoma Health Sciences Center, Oklahoma City, OK (United States)
  3. Massachusetts General Hospital, Boston, MA (United States)
Publication Date:
OSTI Identifier:
22626786
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 43; Journal Issue: 6; Other Information: (c) 2016 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 61 RADIATION PROTECTION AND DOSIMETRY; ACOUSTICS; ALGORITHMS; ANIMAL TISSUES; BIOMEDICAL RADIOGRAPHY; CHEST; COMPUTERIZED TOMOGRAPHY; IMAGE PROCESSING; IMAGES; MAMMARY GLANDS; NEOPLASMS; PATIENTS; PHANTOMS; RADIATION DOSES; SKELETON; SKIN; SPECIFIC HEAT; THERMAL EXPANSION; ULTRASONIC WAVES

Citation Formats

Tang, S, Laaroussi, R, Chen, J, Samant, P, Xiang, L, Chen, Y, Ahmad, S, and Yang, K. SU-F-I-14: 3D Breast Digital Phantom for XACT Imaging. United States: N. p., 2016. Web. doi:10.1118/1.4955842.
Tang, S, Laaroussi, R, Chen, J, Samant, P, Xiang, L, Chen, Y, Ahmad, S, & Yang, K. SU-F-I-14: 3D Breast Digital Phantom for XACT Imaging. United States. doi:10.1118/1.4955842.
Tang, S, Laaroussi, R, Chen, J, Samant, P, Xiang, L, Chen, Y, Ahmad, S, and Yang, K. Wed . "SU-F-I-14: 3D Breast Digital Phantom for XACT Imaging". United States. doi:10.1118/1.4955842.
@article{osti_22626786,
title = {SU-F-I-14: 3D Breast Digital Phantom for XACT Imaging},
author = {Tang, S and Laaroussi, R and Chen, J and Samant, P and Xiang, L and Chen, Y and Ahmad, S and Yang, K},
abstractNote = {Purpose: The X-ray induced acoustic computed tomography (XACT) is a new imaging modality which combines X-ray contrast and high ultrasonic resolution in a single modality. Using XACT in breast imaging, a 3D breast volume can be imaged by only one pulsed X-ray radiation, which could dramatically reduce the imaging dose for patients undergoing breast cancer screening and diagnosis. A 3D digital phantom that contains both X-ray properties and acoustic properties of different tissue types is indeed needed for developing and optimizing the XACT system. The purpose of this study is to offer a realistic breast digital phantom as a valuable tool for improving breast XACT imaging techniques and potentially leading to better diagnostic outcomes. Methods: A series of breast CT images along the coronal plane from a patient who has breast calcifications are used as the source images. A HU value based segmentation algorithm is employed to identify breast tissues in five categories, namely the skin tissue, fat tissue, glandular tissue, chest bone and calcifications. For each pixel, the dose related parameters, such as material components and density, and acoustic related parameters, such as frequency-dependent acoustic attenuation coefficient and bandwidth, are assigned based on tissue types. Meanwhile, other parameters which are used in sound propagation, including the sound speed, thermal expansion coefficient, and heat capacity are also assigned to each tissue. Results: A series of 2D tissue type image is acquired first and the 3D digital breast phantom is obtained by using commercial 3D reconstruction software. When giving specific settings including dose depositions and ultrasound center frequency, the X-ray induced initial pressure rise can be calculated accordingly. Conclusion: The proposed 3D breast digital phantom represents a realistic breast anatomic structure and provides a valuable tool for developing and evaluating the system performance for XACT.},
doi = {10.1118/1.4955842},
journal = {Medical Physics},
number = 6,
volume = 43,
place = {United States},
year = {Wed Jun 15 00:00:00 EDT 2016},
month = {Wed Jun 15 00:00:00 EDT 2016}
}