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Title: SU-F-R-21: The Stability of Radiomics Features On 4D FDG-PET/CT Images

Abstract

Purpose: The aim of our study was to perform a stability analysis of 4D PET-derived features in non-small cell lung carcinoma (NSCLC) based on six different respiratory phases. Methods: The 4D FDG-PET/CT respiratory phases were labeled as T0%, T17%, T33%,T50%, T67%, T83% phases, with the T0% phase approximately corresponding to the normal end-inspiration. Lesions were manually delineated based on fused PET-CT, using a standardized clinical delineation protocol. Six texture parameters were analyzed. Results: Results showed that the majority of assessed features had a low stability such as Homogeneity (0.385–0.416), Dissimilarity (3.707–3.861), Angular two moments (0.013–0.019), Contrast (39.782–49.562), Entropy(4.683–5.002) and Inverse differential moment (0.317–0.362) on different respiratory phases. Conclusion: This study suggest that further research of quantitative PET imaging features is warranted with respect to respiratory motion.

Authors:
 [1]
  1. Shandong Cancer Hospital and Institute, Jinan, Shandong (China)
Publication Date:
OSTI Identifier:
22626745
Resource Type:
Journal Article
Journal Name:
Medical Physics
Additional Journal Information:
Journal Volume: 43; Journal Issue: 6; Other Information: (c) 2016 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-2405
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 61 RADIATION PROTECTION AND DOSIMETRY; APPROXIMATIONS; BIOMEDICAL RADIOGRAPHY; CARCINOMAS; ENTROPY; LUNGS; POSITRON COMPUTED TOMOGRAPHY

Citation Formats

Ma, C. SU-F-R-21: The Stability of Radiomics Features On 4D FDG-PET/CT Images. United States: N. p., 2016. Web. doi:10.1118/1.4955793.
Ma, C. SU-F-R-21: The Stability of Radiomics Features On 4D FDG-PET/CT Images. United States. https://doi.org/10.1118/1.4955793
Ma, C. 2016. "SU-F-R-21: The Stability of Radiomics Features On 4D FDG-PET/CT Images". United States. https://doi.org/10.1118/1.4955793.
@article{osti_22626745,
title = {SU-F-R-21: The Stability of Radiomics Features On 4D FDG-PET/CT Images},
author = {Ma, C},
abstractNote = {Purpose: The aim of our study was to perform a stability analysis of 4D PET-derived features in non-small cell lung carcinoma (NSCLC) based on six different respiratory phases. Methods: The 4D FDG-PET/CT respiratory phases were labeled as T0%, T17%, T33%,T50%, T67%, T83% phases, with the T0% phase approximately corresponding to the normal end-inspiration. Lesions were manually delineated based on fused PET-CT, using a standardized clinical delineation protocol. Six texture parameters were analyzed. Results: Results showed that the majority of assessed features had a low stability such as Homogeneity (0.385–0.416), Dissimilarity (3.707–3.861), Angular two moments (0.013–0.019), Contrast (39.782–49.562), Entropy(4.683–5.002) and Inverse differential moment (0.317–0.362) on different respiratory phases. Conclusion: This study suggest that further research of quantitative PET imaging features is warranted with respect to respiratory motion.},
doi = {10.1118/1.4955793},
url = {https://www.osti.gov/biblio/22626745}, journal = {Medical Physics},
issn = {0094-2405},
number = 6,
volume = 43,
place = {United States},
year = {Wed Jun 15 00:00:00 EDT 2016},
month = {Wed Jun 15 00:00:00 EDT 2016}
}