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Title: SU-C-207A-03: Development of Proton CT Imaging System Using Thick Scintillator and CCD Camera

Abstract

Purpose: In the treatment planning of proton therapy, Water Equivalent Length (WEL), which is the parameter for the calculation of dose and the range of proton, is derived by X-ray CT (xCT) image and xCT-WEL conversion. However, about a few percent error in the accuracy of proton range calculation through this conversion has been reported. The purpose of this study is to construct a proton CT (pCT) imaging system for an evaluation of the error. Methods: The pCT imaging system was constructed with a thick scintillator and a cooled CCD camera, which acquires the two-dimensional image of integrated value of the scintillation light toward the beam direction. The pCT image is reconstructed by FBP method using a correction between the light intensity and residual range of proton beam. An experiment for the demonstration of this system was performed with 70-MeV proton beam provided by NIRS cyclotron. The pCT image of several objects reconstructed from the experimental data was evaluated quantitatively. Results: Three-dimensional pCT images of several objects were reconstructed experimentally. A finestructure of approximately 1 mm was clearly observed. The position resolution of pCT image was almost the same as that of xCT image. And the error of proton CTmore » pixel value was up to 4%. The deterioration of image quality was caused mainly by the effect of multiple Coulomb scattering. Conclusion: We designed and constructed the pCT imaging system using a thick scintillator and a CCD camera. And the system was evaluated with the experiment by use of 70-MeV proton beam. Three-dimensional pCT images of several objects were acquired by the system. This work was supported by JST SENTAN Grant Number 13A1101 and JSPS KAKENHI Grant Number 15H04912.« less

Authors:
;  [1]; ;  [2];  [3];  [4]
  1. The University of Tokyo, Tokyo (Japan)
  2. Hiroshima University, Hiroshima (Japan)
  3. Rikkyo University, Tokyo (Japan)
  4. Tokai University, Isehara (Japan)
Publication Date:
OSTI Identifier:
22624338
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 43; Journal Issue: 6; Other Information: (c) 2016 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 61 RADIATION PROTECTION AND DOSIMETRY; ACCURACY; BIOMEDICAL RADIOGRAPHY; CAMERAS; CHARGE-COUPLED DEVICES; COMPUTERIZED TOMOGRAPHY; CORRECTIONS; COULOMB SCATTERING; ERRORS; EVALUATION; NIRS CYCLOTRON; PLANNING; PROTON BEAMS; RADIATION DOSES; RADIOTHERAPY; SCINTILLATIONS; FUNDAMENTAL INTERACTIONS

Citation Formats

Tanaka, S, Uesaka, M, Nishio, T, Tsuneda, M, Matsushita, K, and Kabuki, S. SU-C-207A-03: Development of Proton CT Imaging System Using Thick Scintillator and CCD Camera. United States: N. p., 2016. Web. doi:10.1118/1.4955578.
Tanaka, S, Uesaka, M, Nishio, T, Tsuneda, M, Matsushita, K, & Kabuki, S. SU-C-207A-03: Development of Proton CT Imaging System Using Thick Scintillator and CCD Camera. United States. doi:10.1118/1.4955578.
Tanaka, S, Uesaka, M, Nishio, T, Tsuneda, M, Matsushita, K, and Kabuki, S. Wed . "SU-C-207A-03: Development of Proton CT Imaging System Using Thick Scintillator and CCD Camera". United States. doi:10.1118/1.4955578.
@article{osti_22624338,
title = {SU-C-207A-03: Development of Proton CT Imaging System Using Thick Scintillator and CCD Camera},
author = {Tanaka, S and Uesaka, M and Nishio, T and Tsuneda, M and Matsushita, K and Kabuki, S},
abstractNote = {Purpose: In the treatment planning of proton therapy, Water Equivalent Length (WEL), which is the parameter for the calculation of dose and the range of proton, is derived by X-ray CT (xCT) image and xCT-WEL conversion. However, about a few percent error in the accuracy of proton range calculation through this conversion has been reported. The purpose of this study is to construct a proton CT (pCT) imaging system for an evaluation of the error. Methods: The pCT imaging system was constructed with a thick scintillator and a cooled CCD camera, which acquires the two-dimensional image of integrated value of the scintillation light toward the beam direction. The pCT image is reconstructed by FBP method using a correction between the light intensity and residual range of proton beam. An experiment for the demonstration of this system was performed with 70-MeV proton beam provided by NIRS cyclotron. The pCT image of several objects reconstructed from the experimental data was evaluated quantitatively. Results: Three-dimensional pCT images of several objects were reconstructed experimentally. A finestructure of approximately 1 mm was clearly observed. The position resolution of pCT image was almost the same as that of xCT image. And the error of proton CT pixel value was up to 4%. The deterioration of image quality was caused mainly by the effect of multiple Coulomb scattering. Conclusion: We designed and constructed the pCT imaging system using a thick scintillator and a CCD camera. And the system was evaluated with the experiment by use of 70-MeV proton beam. Three-dimensional pCT images of several objects were acquired by the system. This work was supported by JST SENTAN Grant Number 13A1101 and JSPS KAKENHI Grant Number 15H04912.},
doi = {10.1118/1.4955578},
journal = {Medical Physics},
number = 6,
volume = 43,
place = {United States},
year = {Wed Jun 15 00:00:00 EDT 2016},
month = {Wed Jun 15 00:00:00 EDT 2016}
}