skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: What happens when spins meet for ionizing radiation dosimetry?

Abstract

Electron spin resonance (ESR) and magnetic resonance imaging (MRI) can be used to measure radiation dose deposited in different milieu through its effects. Radiation can break chemical bonds and if they produce stable free radicals, ESR can measure their concentration through their spins and a dose can be inferred. Ionizing radiation can also promote polymerization and in this case proton relaxation times can be measured and an image weighed by T2 can be produced giving spatial information about dose. A review of the basics of these applications is presented concluding with an end-to-end test using a composite Gel-Alanine phantom to validate 3-dimensionally dose distribution delivered in a simulation of Volume Modulated Arch Therapy on the simultaneous treatment of multiple brain metastases. The results obtained with the gel and alanine dosimeters are consistent with the expected by the treatment planning system, showing the potential of this multidosimetric approach and validating dosimetrically the multiple brain metastases treatment using VMAT.

Authors:
;  [1];  [2]
  1. Departamento de Física e Matemática, FFCLRP, Universidade de São Paulo, Av. Bandeirantes 3900, 14040-901, Monte Alegre, Ribeirão Preto, SP - Brazil (Brazil)
  2. Hospital Sírio Libanês, R. Dona Adma Jafet 91, 01308-000, Bela Vista, São Paulo, SP – Brazil (Brazil)
Publication Date:
OSTI Identifier:
22608539
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 1753; Journal Issue: 1; Conference: Latin American symposium on nuclear physics and applications, Medellin (Colombia), 30 Nov - 4 Dec 2015; Other Information: (c) 2016 Author(s); Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ABUNDANCE; BRAIN; CHEMICAL BONDS; CONCENTRATION RATIO; DOSIMETRY; ELECTRON SPIN RESONANCE; IONIZING RADIATIONS; METASTASES; NMR IMAGING; PHANTOMS; POLYMERIZATION; PROTONS; RADIATION DOSE DISTRIBUTIONS; RADIATION DOSES; RADIOTHERAPY; RELAXATION; REVIEWS; SIMULATION; THREE-DIMENSIONAL CALCULATIONS

Citation Formats

Pavoni, Juliana F., Baffa, Oswaldo, E-mail: baffa@usp.br, and Neves-Junior, Wellington F. P.. What happens when spins meet for ionizing radiation dosimetry?. United States: N. p., 2016. Web. doi:10.1063/1.4955393.
Pavoni, Juliana F., Baffa, Oswaldo, E-mail: baffa@usp.br, & Neves-Junior, Wellington F. P.. What happens when spins meet for ionizing radiation dosimetry?. United States. doi:10.1063/1.4955393.
Pavoni, Juliana F., Baffa, Oswaldo, E-mail: baffa@usp.br, and Neves-Junior, Wellington F. P.. 2016. "What happens when spins meet for ionizing radiation dosimetry?". United States. doi:10.1063/1.4955393.
@article{osti_22608539,
title = {What happens when spins meet for ionizing radiation dosimetry?},
author = {Pavoni, Juliana F. and Baffa, Oswaldo, E-mail: baffa@usp.br and Neves-Junior, Wellington F. P.},
abstractNote = {Electron spin resonance (ESR) and magnetic resonance imaging (MRI) can be used to measure radiation dose deposited in different milieu through its effects. Radiation can break chemical bonds and if they produce stable free radicals, ESR can measure their concentration through their spins and a dose can be inferred. Ionizing radiation can also promote polymerization and in this case proton relaxation times can be measured and an image weighed by T2 can be produced giving spatial information about dose. A review of the basics of these applications is presented concluding with an end-to-end test using a composite Gel-Alanine phantom to validate 3-dimensionally dose distribution delivered in a simulation of Volume Modulated Arch Therapy on the simultaneous treatment of multiple brain metastases. The results obtained with the gel and alanine dosimeters are consistent with the expected by the treatment planning system, showing the potential of this multidosimetric approach and validating dosimetrically the multiple brain metastases treatment using VMAT.},
doi = {10.1063/1.4955393},
journal = {AIP Conference Proceedings},
number = 1,
volume = 1753,
place = {United States},
year = 2016,
month = 7
}