Quantum dots in nanomedicine: recent trends, advances and unresolved issues

doi:https://doi.org/10.1016/J.BBRC.2015.07.039

Title: Quantum dots in nanomedicine: recent trends, advances and unresolved issues

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Abstract

The review addresses the current state of progress in the use of ultra-small nanoparticles from the category of quantum dots (QDs), which presently embraces a widening range of nanomaterials of different nature, including “classical” semiconductor groups III-V and II-VI nanocrystals, along with more recently emerged carbon, silicon, gold and other types of nanoparticles falling into this class of nanomaterials due to their similar physical characteristics such as small size and associated quantum confinement effects. A diverse range of QDs applications in nanomedicine has been extensively summarised previously in numerous publications. Therefore, this review is not intended to provide an all-embracing survey of the well documented QDs uses, but is rather focused on the most recent emerging developments, concepts and outstanding unresolved problematic and sometimes controversial issues. Over 125 publications are overviewed and discussed here in the context of major nanomedicine domains, i.e. medical imaging, diagnostics, therapeutic applications and combination of them in multifunctional theranostic systems. - Highlights: • New types of nanomaterials have been recently added to the category of QDs with a potential in nanomedicine. • Within the main nanomedicine domains, best progress has been achieved with QDs for diagnostic tools. • Further studies are required for the theranosticmore »« less

Authors:: Volkov, Yuri

Publication Date:: 2015-12-18

OSTI Identifier:: 22594130

Resource Type:: Journal Article

Journal Name:: Biochemical and Biophysical Research Communications

Additional Journal Information:: Journal Volume: 468; Journal Issue: 3; Other Information: Copyright (c) 2015 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0006-291X

Country of Publication:: United States

Language:: English

Subject:: 77 NANOSCIENCE AND NANOTECHNOLOGY; BIOMEDICAL RADIOGRAPHY; DIAGNOSTIC USES; MEDICINE; NANOMATERIALS; NANOPARTICLES; QUANTUM DOTS; THERAPEUTIC USES

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                    Volkov, Yuri. Quantum dots in nanomedicine: recent trends, advances and unresolved issues.  United States: N. p., 2015. 
        Web.  doi:10.1016/J.BBRC.2015.07.039.

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                    Volkov, Yuri. Quantum dots in nanomedicine: recent trends, advances and unresolved issues.  United States.  https://doi.org/10.1016/J.BBRC.2015.07.039

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                    Volkov, Yuri. Fri .  
        "Quantum dots in nanomedicine: recent trends, advances and unresolved issues".  United States.  https://doi.org/10.1016/J.BBRC.2015.07.039.

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@article{osti_22594130,

  title        = {Quantum dots in nanomedicine: recent trends, advances and unresolved issues},

  author       = {Volkov, Yuri},

  abstractNote = {The review addresses the current state of progress in the use of ultra-small nanoparticles from the category of quantum dots (QDs), which presently embraces a widening range of nanomaterials of different nature, including “classical” semiconductor groups III-V and II-VI nanocrystals, along with more recently emerged carbon, silicon, gold and other types of nanoparticles falling into this class of nanomaterials due to their similar physical characteristics such as small size and associated quantum confinement effects. A diverse range of QDs applications in nanomedicine has been extensively summarised previously in numerous publications. Therefore, this review is not intended to provide an all-embracing survey of the well documented QDs uses, but is rather focused on the most recent emerging developments, concepts and outstanding unresolved problematic and sometimes controversial issues. Over 125 publications are overviewed and discussed here in the context of major nanomedicine domains, i.e. medical imaging, diagnostics, therapeutic applications and combination of them in multifunctional theranostic systems. - Highlights: • New types of nanomaterials have been recently added to the category of QDs with a potential in nanomedicine. • Within the main nanomedicine domains, best progress has been achieved with QDs for diagnostic tools. • Further studies are required for the theranostic QDs-based leads to reach clinical translation.},

  doi          = {10.1016/J.BBRC.2015.07.039},

  url          = {https://www.osti.gov/biblio/22594130},
  journal      = {Biochemical and Biophysical Research Communications},

  issn         = {0006-291X},

  number       = 3,

  volume       = 468,

  place        = {United States},

  year         = {2015},

  month        = {12}

}

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