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Title: Quantum dots in nanomedicine: recent trends, advances and unresolved issues

Abstract

The review addresses the current state of progress in the use of ultra-small nanoparticles from the category of quantum dots (QDs), which presently embraces a widening range of nanomaterials of different nature, including “classical” semiconductor groups III-V and II-VI nanocrystals, along with more recently emerged carbon, silicon, gold and other types of nanoparticles falling into this class of nanomaterials due to their similar physical characteristics such as small size and associated quantum confinement effects. A diverse range of QDs applications in nanomedicine has been extensively summarised previously in numerous publications. Therefore, this review is not intended to provide an all-embracing survey of the well documented QDs uses, but is rather focused on the most recent emerging developments, concepts and outstanding unresolved problematic and sometimes controversial issues. Over 125 publications are overviewed and discussed here in the context of major nanomedicine domains, i.e. medical imaging, diagnostics, therapeutic applications and combination of them in multifunctional theranostic systems. - Highlights: • New types of nanomaterials have been recently added to the category of QDs with a potential in nanomedicine. • Within the main nanomedicine domains, best progress has been achieved with QDs for diagnostic tools. • Further studies are required for the theranosticmore » QDs-based leads to reach clinical translation.« less

Authors:
Publication Date:
OSTI Identifier:
22594130
Resource Type:
Journal Article
Journal Name:
Biochemical and Biophysical Research Communications
Additional Journal Information:
Journal Volume: 468; Journal Issue: 3; Other Information: Copyright (c) 2015 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0006-291X
Country of Publication:
United States
Language:
English
Subject:
77 NANOSCIENCE AND NANOTECHNOLOGY; BIOMEDICAL RADIOGRAPHY; DIAGNOSTIC USES; MEDICINE; NANOMATERIALS; NANOPARTICLES; QUANTUM DOTS; THERAPEUTIC USES

Citation Formats

Volkov, Yuri. Quantum dots in nanomedicine: recent trends, advances and unresolved issues. United States: N. p., 2015. Web. doi:10.1016/J.BBRC.2015.07.039.
Volkov, Yuri. Quantum dots in nanomedicine: recent trends, advances and unresolved issues. United States. https://doi.org/10.1016/J.BBRC.2015.07.039
Volkov, Yuri. Fri . "Quantum dots in nanomedicine: recent trends, advances and unresolved issues". United States. https://doi.org/10.1016/J.BBRC.2015.07.039.
@article{osti_22594130,
title = {Quantum dots in nanomedicine: recent trends, advances and unresolved issues},
author = {Volkov, Yuri},
abstractNote = {The review addresses the current state of progress in the use of ultra-small nanoparticles from the category of quantum dots (QDs), which presently embraces a widening range of nanomaterials of different nature, including “classical” semiconductor groups III-V and II-VI nanocrystals, along with more recently emerged carbon, silicon, gold and other types of nanoparticles falling into this class of nanomaterials due to their similar physical characteristics such as small size and associated quantum confinement effects. A diverse range of QDs applications in nanomedicine has been extensively summarised previously in numerous publications. Therefore, this review is not intended to provide an all-embracing survey of the well documented QDs uses, but is rather focused on the most recent emerging developments, concepts and outstanding unresolved problematic and sometimes controversial issues. Over 125 publications are overviewed and discussed here in the context of major nanomedicine domains, i.e. medical imaging, diagnostics, therapeutic applications and combination of them in multifunctional theranostic systems. - Highlights: • New types of nanomaterials have been recently added to the category of QDs with a potential in nanomedicine. • Within the main nanomedicine domains, best progress has been achieved with QDs for diagnostic tools. • Further studies are required for the theranostic QDs-based leads to reach clinical translation.},
doi = {10.1016/J.BBRC.2015.07.039},
url = {https://www.osti.gov/biblio/22594130}, journal = {Biochemical and Biophysical Research Communications},
issn = {0006-291X},
number = 3,
volume = 468,
place = {United States},
year = {2015},
month = {12}
}