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Title: Segmented slant hole collimator for stationary cardiac SPECT: Monte Carlo simulations

Abstract

Purpose: This work is a preliminary study of a stationary cardiac SPECT system. The goal of this research is to propose a stationary cardiac SPECT system using segmented slant-hole collimators and to perform computer simulations to test the feasibility. Compared to the rotational SPECT, a stationary system has a benefit of acquiring temporally consistent projections. The most challenging issue in building a stationary system is to provide sufficient projection view-angles. Methods: A GATE (GEANT4 application for tomographic emission) Monte Carlo model was developed to simulate a two-detector stationary cardiac SPECT that uses segmented slant-hole collimators. Each detector contains seven segmented slant-hole sections that slant to a common volume at the rotation center. Consequently, 14 view-angles over 180° were acquired without any gantry rotation. The NCAT phantom was used for data generation and a tailored maximum-likelihood expectation-maximization algorithm was used for image reconstruction. Effects of limited number of view-angles and data truncation were carefully evaluated in the paper. Results: Simulation results indicated that the proposed segmented slant-hole stationary cardiac SPECT system is able to acquire sufficient data for cardiac imaging without a loss of image quality, even when the uptakes in the liver and kidneys are high. Seven views are acquiredmore » simultaneously at each detector, leading to 5-fold sensitivity gain over the conventional dual-head system at the same total acquisition time, which in turn increases the signal-to-noise ratio by 19%. The segmented slant-hole SPECT system also showed a good performance in lesion detection. In our prototype system, a short hole-length was used to reduce the dead zone between neighboring collimator segments. The measured sensitivity gain is about 17-fold over the conventional dual-head system. Conclusions: The GATE Monte Carlo simulations confirm the feasibility of the proposed stationary cardiac SPECT system with segmented slant-hole collimators. The proposed collimator consists of combined parallel and slant holes, and the image on the detector is not reduced in size.« less

Authors:
 [1];  [2];  [3]
  1. Department of Radiology, Utah Center for Advanced Imaging Research (UCAIR), University of Utah, Salt Lake City, Utah 84108 and Department of Bioengineering, University of Utah, Salt Lake City, Utah 84112 (United States)
  2. Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905 (United States)
  3. Department of Radiology, Utah Center for Advanced Imaging Research (UCAIR), University of Utah, Salt Lake City, Utah 84108 and Department of Engineering, Weber State University, Ogden, Utah 84408 (United States)
Publication Date:
OSTI Identifier:
22581368
Resource Type:
Journal Article
Journal Name:
Medical Physics
Additional Journal Information:
Journal Volume: 42; Journal Issue: 9; Other Information: (c) 2015 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-2405
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 61 RADIATION PROTECTION AND DOSIMETRY; ALGORITHMS; BIOMEDICAL RADIOGRAPHY; COLLIMATORS; COMPARATIVE EVALUATIONS; COMPUTERIZED SIMULATION; IMAGE PROCESSING; IMAGES; KIDNEYS; LIVER; MONTE CARLO METHOD; PHANTOMS; SIGNAL-TO-NOISE RATIO; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY

Citation Formats

Mao, Yanfei, Yu, Zhicong, and Zeng, Gengsheng L. Segmented slant hole collimator for stationary cardiac SPECT: Monte Carlo simulations. United States: N. p., 2015. Web. doi:10.1118/1.4928484.
Mao, Yanfei, Yu, Zhicong, & Zeng, Gengsheng L. Segmented slant hole collimator for stationary cardiac SPECT: Monte Carlo simulations. United States. doi:10.1118/1.4928484.
Mao, Yanfei, Yu, Zhicong, and Zeng, Gengsheng L. Tue . "Segmented slant hole collimator for stationary cardiac SPECT: Monte Carlo simulations". United States. doi:10.1118/1.4928484.
@article{osti_22581368,
title = {Segmented slant hole collimator for stationary cardiac SPECT: Monte Carlo simulations},
author = {Mao, Yanfei and Yu, Zhicong and Zeng, Gengsheng L.},
abstractNote = {Purpose: This work is a preliminary study of a stationary cardiac SPECT system. The goal of this research is to propose a stationary cardiac SPECT system using segmented slant-hole collimators and to perform computer simulations to test the feasibility. Compared to the rotational SPECT, a stationary system has a benefit of acquiring temporally consistent projections. The most challenging issue in building a stationary system is to provide sufficient projection view-angles. Methods: A GATE (GEANT4 application for tomographic emission) Monte Carlo model was developed to simulate a two-detector stationary cardiac SPECT that uses segmented slant-hole collimators. Each detector contains seven segmented slant-hole sections that slant to a common volume at the rotation center. Consequently, 14 view-angles over 180° were acquired without any gantry rotation. The NCAT phantom was used for data generation and a tailored maximum-likelihood expectation-maximization algorithm was used for image reconstruction. Effects of limited number of view-angles and data truncation were carefully evaluated in the paper. Results: Simulation results indicated that the proposed segmented slant-hole stationary cardiac SPECT system is able to acquire sufficient data for cardiac imaging without a loss of image quality, even when the uptakes in the liver and kidneys are high. Seven views are acquired simultaneously at each detector, leading to 5-fold sensitivity gain over the conventional dual-head system at the same total acquisition time, which in turn increases the signal-to-noise ratio by 19%. The segmented slant-hole SPECT system also showed a good performance in lesion detection. In our prototype system, a short hole-length was used to reduce the dead zone between neighboring collimator segments. The measured sensitivity gain is about 17-fold over the conventional dual-head system. Conclusions: The GATE Monte Carlo simulations confirm the feasibility of the proposed stationary cardiac SPECT system with segmented slant-hole collimators. The proposed collimator consists of combined parallel and slant holes, and the image on the detector is not reduced in size.},
doi = {10.1118/1.4928484},
journal = {Medical Physics},
issn = {0094-2405},
number = 9,
volume = 42,
place = {United States},
year = {2015},
month = {9}
}