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Title: Mueller-matrix mapping of biological tissues in differential diagnosis of optical anisotropy mechanisms of protein networks

Abstract

We report a model of Mueller-matrix description of optical anisotropy of protein networks in biological tissues with allowance for the linear birefringence and dichroism. The model is used to construct the reconstruction algorithms of coordinate distributions of phase shifts and the linear dichroism coefficient. In the statistical analysis of such distributions, we have found the objective criteria of differentiation between benign and malignant tissues of the female reproductive system. From the standpoint of evidence-based medicine, we have determined the operating characteristics (sensitivity, specificity and accuracy) of the Mueller-matrix reconstruction method of optical anisotropy parameters and demonstrated its effectiveness in the differentiation of benign and malignant tumours. (laser applications and other topics in quantum electronics)

Authors:
;  [1]; ; ;  [2]
  1. Yuriy Fedkovych Chernivtsi National University, Chernivtsi (Ukraine)
  2. Bukovinian State Medical University, Chernivtsi (Ukraine)
Publication Date:
OSTI Identifier:
22551297
Resource Type:
Journal Article
Resource Relation:
Journal Name: Quantum Electronics (Woodbury, N.Y.); Journal Volume: 45; Journal Issue: 3; Other Information: Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; 72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS; ACCURACY; ALGORITHMS; ANIMAL TISSUES; ANISOTROPY; BIREFRINGENCE; DICHROISM; MAPPING; MATRICES; NEOPLASMS; PHASE SHIFT; PROTEINS; SENSITIVITY; SPECIFICITY

Citation Formats

Ushenko, V A, Sidor, M I, Marchuk, Yu F, Pashkovskaya, N V, and Andreichuk, D R. Mueller-matrix mapping of biological tissues in differential diagnosis of optical anisotropy mechanisms of protein networks. United States: N. p., 2015. Web. doi:10.1070/QE2015V045N03ABEH015333.
Ushenko, V A, Sidor, M I, Marchuk, Yu F, Pashkovskaya, N V, & Andreichuk, D R. Mueller-matrix mapping of biological tissues in differential diagnosis of optical anisotropy mechanisms of protein networks. United States. doi:10.1070/QE2015V045N03ABEH015333.
Ushenko, V A, Sidor, M I, Marchuk, Yu F, Pashkovskaya, N V, and Andreichuk, D R. Tue . "Mueller-matrix mapping of biological tissues in differential diagnosis of optical anisotropy mechanisms of protein networks". United States. doi:10.1070/QE2015V045N03ABEH015333.
@article{osti_22551297,
title = {Mueller-matrix mapping of biological tissues in differential diagnosis of optical anisotropy mechanisms of protein networks},
author = {Ushenko, V A and Sidor, M I and Marchuk, Yu F and Pashkovskaya, N V and Andreichuk, D R},
abstractNote = {We report a model of Mueller-matrix description of optical anisotropy of protein networks in biological tissues with allowance for the linear birefringence and dichroism. The model is used to construct the reconstruction algorithms of coordinate distributions of phase shifts and the linear dichroism coefficient. In the statistical analysis of such distributions, we have found the objective criteria of differentiation between benign and malignant tissues of the female reproductive system. From the standpoint of evidence-based medicine, we have determined the operating characteristics (sensitivity, specificity and accuracy) of the Mueller-matrix reconstruction method of optical anisotropy parameters and demonstrated its effectiveness in the differentiation of benign and malignant tumours. (laser applications and other topics in quantum electronics)},
doi = {10.1070/QE2015V045N03ABEH015333},
journal = {Quantum Electronics (Woodbury, N.Y.)},
number = 3,
volume = 45,
place = {United States},
year = {Tue Mar 31 00:00:00 EDT 2015},
month = {Tue Mar 31 00:00:00 EDT 2015}
}