SU-E-T-516: Investigation of a Novel Radiochromic Radiation Reporting System Utilizing the Reduction of Ferric Ion
Abstract
Purpose To introduce and characterize a new “reverse-Fricke” radiation reporting system utilizing the reduction of ferric ions (Fe{sup 3+}) to ferrous ions (Fe{sup 2+}). Methods Two formulations of the radiochromic reporting system, referred to as A and B, were prepared for investigation. Formulation-A consisted of 14 mM 1,10-phenanthroline, 42 mM ethanol, and 57 mM ammonium ferric oxalate in water. Formulation-B consisted of 27 mM 1,10-phenanthroline, 42 mM ethanol, and 28 mM ammonium ferric oxalate in water. Solutions were prepared immediately prior to irradiation with a Cobalt-60 unit with radiation doses of 0, 1, 5, 10, 15, 20, and 25 Gy. The change in optical density over the visible range of 450–650 nm was measured using a spectrophotometer immediately after irradiation. The effective atomic numbers of the formulations were calculated using Mayneord’s formula. Results Ionizing radiation energy absorbed in the solutions causes the reduction of ferric ions (Fe{sup 3+}) into ferrous ions (Fe{sup 2+}), which then forms a 1:3 red colored complex with 1,10-phenanthroline ([(C{sub 1} {sub 2}H{sub 8}N{sup 2}){sub 3}Fe]{sup 2+}) that can be measured spectrophotometrically. The absorbance spectra of the resulting complex displayed a peak maximum at 512 nm with a greater change in absorbance for Formulation-B after receivingmore »
- Authors:
-
- UT MD Anderson Cancer Center, Houston, TX (United States)
- The University of South Australia, South Australia, SA (Australia)
- Publication Date:
- OSTI Identifier:
- 22548554
- Resource Type:
- Journal Article
- Journal Name:
- Medical Physics
- Additional Journal Information:
- Journal Volume: 42; Journal Issue: 6; Other Information: (c) 2015 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-2405
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES; AQUEOUS SOLUTIONS; COBALT 60; ETHANOL; IONIZING RADIATIONS; IRON IONS; IRRADIATION; MATRIX MATERIALS; OXALATES; PHENANTHROLINES; RADIATION DOSES; SPECTROPHOTOMETERS
Citation Formats
Lee, H, Alqathami, M, Wang, J, Ibbott, G, and Blencowe, A. SU-E-T-516: Investigation of a Novel Radiochromic Radiation Reporting System Utilizing the Reduction of Ferric Ion. United States: N. p., 2015.
Web. doi:10.1118/1.4924878.
Lee, H, Alqathami, M, Wang, J, Ibbott, G, & Blencowe, A. SU-E-T-516: Investigation of a Novel Radiochromic Radiation Reporting System Utilizing the Reduction of Ferric Ion. United States. https://doi.org/10.1118/1.4924878
Lee, H, Alqathami, M, Wang, J, Ibbott, G, and Blencowe, A. 2015.
"SU-E-T-516: Investigation of a Novel Radiochromic Radiation Reporting System Utilizing the Reduction of Ferric Ion". United States. https://doi.org/10.1118/1.4924878.
@article{osti_22548554,
title = {SU-E-T-516: Investigation of a Novel Radiochromic Radiation Reporting System Utilizing the Reduction of Ferric Ion},
author = {Lee, H and Alqathami, M and Wang, J and Ibbott, G and Blencowe, A},
abstractNote = {Purpose To introduce and characterize a new “reverse-Fricke” radiation reporting system utilizing the reduction of ferric ions (Fe{sup 3+}) to ferrous ions (Fe{sup 2+}). Methods Two formulations of the radiochromic reporting system, referred to as A and B, were prepared for investigation. Formulation-A consisted of 14 mM 1,10-phenanthroline, 42 mM ethanol, and 57 mM ammonium ferric oxalate in water. Formulation-B consisted of 27 mM 1,10-phenanthroline, 42 mM ethanol, and 28 mM ammonium ferric oxalate in water. Solutions were prepared immediately prior to irradiation with a Cobalt-60 unit with radiation doses of 0, 1, 5, 10, 15, 20, and 25 Gy. The change in optical density over the visible range of 450–650 nm was measured using a spectrophotometer immediately after irradiation. The effective atomic numbers of the formulations were calculated using Mayneord’s formula. Results Ionizing radiation energy absorbed in the solutions causes the reduction of ferric ions (Fe{sup 3+}) into ferrous ions (Fe{sup 2+}), which then forms a 1:3 red colored complex with 1,10-phenanthroline ([(C{sub 1} {sub 2}H{sub 8}N{sup 2}){sub 3}Fe]{sup 2+}) that can be measured spectrophotometrically. The absorbance spectra of the resulting complex displayed a peak maximum at 512 nm with a greater change in absorbance for Formulation-B after receiving comparable radiation doses. The change in absorbance relative to dose exhibited a linear response up to 25 Gy for both Formulation-A (R{sup 2} = 0.98) and Formulation-B (R{sup 2} = 0.97). The novel formulations were also nearly water equivalent (Zeff = 7.42) with effective atomic numbers of 7.65 and 7.52 and mass densities within 0.2% of water. Conclusion Both formulations displayed visible Fe{sup 2+} complex formation with 1,10-phenanthroline after irradiation using a Cobalt-60 source. The higher sensitivity measured for Formulation-B is attributed to the increase in 1,10-phenanthroline concentration and the increase in the 1,10-phenanthroline to ammonium ferric oxalate ratio. Further investigation of this radiation reporting system in a 3D matrix material is encouraged. NSF GRFP Grant Award #LH-102SPS.},
doi = {10.1118/1.4924878},
url = {https://www.osti.gov/biblio/22548554},
journal = {Medical Physics},
issn = {0094-2405},
number = 6,
volume = 42,
place = {United States},
year = {Mon Jun 15 00:00:00 EDT 2015},
month = {Mon Jun 15 00:00:00 EDT 2015}
}