skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: SU-E-T-651: Quantification of Dosimetric Accuracy of Respiratory Gated Stereotactic Body Radiation Therapy

Abstract

Purpose: To quantify the dosimetric accuracy of respiratory gated stereotactic body radiation therapy delivery using dynamic thorax phantom. Methods: Three patients with mobile target (2 lung, 1liver) were chosen. Retrospective 4DCT image sets were acquired for using Varian RPM system. An in-house MATLAB program was designed for MIP, MinIP and AvgIP generation. ITV was contoured on MIP image set for lung patients and on MinIP for liver patient. Dynamic IMRT plans were generated on selected phase bin image set in Eclipse (v10.0) planning system. CIRS dynamic thorax phantom was used to perform the dosimetric quality assurance. Patient breathing pattern file from RPM system was converted to phantom compatible file by an in-house MATLAB program. This respiratory pattern fed to the CIRS dynamic thorax phantom. 4DCT image set was acquired for this phantom using patient breathing pattern. Verification plans were generated using patient gating window and delivered on the phantom. Measurements were carried out using with ion chamber and EBT2 film. Exposed films were analyzed and evaluated in FilmQA software. Results: The stability of gated output in comparison with un-gated output was within 0.5%. The Ion chamber measured and TPS calculated dose compared for all the patients. The difference observed wasmore » 0.45%, −0.52% and −0.54 for Patient 1, Patient2 and Patient 3 respectively.Gamma value evaluated from EBT film shows pass rates from 92.41% to 99.93% for 3% dose difference and 3mm distance to agreement criteria. Conclusion: Dosimetric accuracy of respiratory gated SBRT delivery for lung and liver was dosimetrically acceptable. The Ion chamber measured dose was within 0.203±0.5659% of the expected dose. Gamma pass rates were within 96.63±3.84% of the expected dose.« less

Authors:
; ; ; ;  [1]; ;  [2];  [3]; ;  [4]
  1. Medanta The Medicity, Gurgaon, Haryana (India)
  2. VIT University, Vellore, Tamil Nadu (India)
  3. Nayati Healathcare and Research Pvt Ltd, Mathura, Uttar pradesh (India)
  4. Rajiv Gandhi Cancer Institute & Research Centre, Gurgaon, Haryana (India)
Publication Date:
OSTI Identifier:
22538160
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 42; Journal Issue: 6; Other Information: (c) 2015 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 61 RADIATION PROTECTION AND DOSIMETRY; ACCURACY; CHEST; COMPUTER CODES; FILM DOSIMETRY; IMAGES; IONIZATION CHAMBERS; LIVER; LUNGS; PATIENTS; PHANTOMS; QUALITY ASSURANCE; RADIATION DOSES; RADIOTHERAPY

Citation Formats

Thiyagarajan, Rajesh, Vikraman, S, Maragathaveni, S, Dhivya, N, Kataria, Tejinder, Nambiraj, N Arunai, Sigamani, Ashokkumar, Sinha, Sujit Nath, Yadav, Girigesh, and Raman, Kothanda. SU-E-T-651: Quantification of Dosimetric Accuracy of Respiratory Gated Stereotactic Body Radiation Therapy. United States: N. p., 2015. Web. doi:10.1118/1.4925014.
Thiyagarajan, Rajesh, Vikraman, S, Maragathaveni, S, Dhivya, N, Kataria, Tejinder, Nambiraj, N Arunai, Sigamani, Ashokkumar, Sinha, Sujit Nath, Yadav, Girigesh, & Raman, Kothanda. SU-E-T-651: Quantification of Dosimetric Accuracy of Respiratory Gated Stereotactic Body Radiation Therapy. United States. doi:10.1118/1.4925014.
Thiyagarajan, Rajesh, Vikraman, S, Maragathaveni, S, Dhivya, N, Kataria, Tejinder, Nambiraj, N Arunai, Sigamani, Ashokkumar, Sinha, Sujit Nath, Yadav, Girigesh, and Raman, Kothanda. Mon . "SU-E-T-651: Quantification of Dosimetric Accuracy of Respiratory Gated Stereotactic Body Radiation Therapy". United States. doi:10.1118/1.4925014.
@article{osti_22538160,
title = {SU-E-T-651: Quantification of Dosimetric Accuracy of Respiratory Gated Stereotactic Body Radiation Therapy},
author = {Thiyagarajan, Rajesh and Vikraman, S and Maragathaveni, S and Dhivya, N and Kataria, Tejinder and Nambiraj, N Arunai and Sigamani, Ashokkumar and Sinha, Sujit Nath and Yadav, Girigesh and Raman, Kothanda},
abstractNote = {Purpose: To quantify the dosimetric accuracy of respiratory gated stereotactic body radiation therapy delivery using dynamic thorax phantom. Methods: Three patients with mobile target (2 lung, 1liver) were chosen. Retrospective 4DCT image sets were acquired for using Varian RPM system. An in-house MATLAB program was designed for MIP, MinIP and AvgIP generation. ITV was contoured on MIP image set for lung patients and on MinIP for liver patient. Dynamic IMRT plans were generated on selected phase bin image set in Eclipse (v10.0) planning system. CIRS dynamic thorax phantom was used to perform the dosimetric quality assurance. Patient breathing pattern file from RPM system was converted to phantom compatible file by an in-house MATLAB program. This respiratory pattern fed to the CIRS dynamic thorax phantom. 4DCT image set was acquired for this phantom using patient breathing pattern. Verification plans were generated using patient gating window and delivered on the phantom. Measurements were carried out using with ion chamber and EBT2 film. Exposed films were analyzed and evaluated in FilmQA software. Results: The stability of gated output in comparison with un-gated output was within 0.5%. The Ion chamber measured and TPS calculated dose compared for all the patients. The difference observed was 0.45%, −0.52% and −0.54 for Patient 1, Patient2 and Patient 3 respectively.Gamma value evaluated from EBT film shows pass rates from 92.41% to 99.93% for 3% dose difference and 3mm distance to agreement criteria. Conclusion: Dosimetric accuracy of respiratory gated SBRT delivery for lung and liver was dosimetrically acceptable. The Ion chamber measured dose was within 0.203±0.5659% of the expected dose. Gamma pass rates were within 96.63±3.84% of the expected dose.},
doi = {10.1118/1.4925014},
journal = {Medical Physics},
number = 6,
volume = 42,
place = {United States},
year = {Mon Jun 15 00:00:00 EDT 2015},
month = {Mon Jun 15 00:00:00 EDT 2015}
}