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Title: SU-E-J-25: End-To-End (E2E) Testing On TomoHDA System Using a Real Pig Head for Intracranial Radiosurgery

Abstract

Purpose: To determine the MVCT imaging uncertainty on the TomoHDA system for intracranial radiosurgery treatments. To determine the end-to-end (E2E) overall accuracy of the TomoHDA system for intracranial radiosurgery. Methods: A pig head was obtained from the butcher, cut coronally through the brain, and preserved in formaldehyde. The base of the head was fixed to a positioning plate allowing precise movement, i.e. translation and rotation, in all 6 axes. A repeatability test was performed on the pig head to determine uncertainty in the image bone registration algorithm. Furthermore, the test studied images with MVCT slice thicknesses of 1 and 3 mm in unison with differing scan lengths. A sensitivity test was performed to determine the registration algorithm’s ability to find the absolute position of known translations/rotations of the pig head. The algorithm’s ability to determine absolute position was compared against that of manual operators, i.e. a radiation therapist and radiation oncologist. Finally, E2E tests for intracranial radiosurgery were performed by measuring the delivered dose distributions within the pig head using Gafchromic films. Results: The repeatability test uncertainty was lowest for the MVCTs of 1-mm slice thickness, which measured less than 0.10 mm and 0.12 deg for all axes. For themore » sensitivity tests, the bone registration algorithm performed better than human eyes and a maximum difference of 0.3 mm and 0.4 deg was observed for the axes. E2E test results in absolute position difference measured 0.03 ± 0.21 mm in x-axis and 0.28 ± 0.18 mm in y-axis. A maximum difference of 0.32 and 0.66 mm was observed in x and y, respectively. The average peak dose difference between measured and calculated dose was 2.7 cGy or 0.4%. Conclusion: Our tests using a pig head phantom estimate the TomoHDA system to have a submillimeter overall accuracy for intracranial radiosurgery.« less

Authors:
; ; ;  [1]
  1. Clinica Luganese, Radiotherapy Center, Lugano (Switzerland)
Publication Date:
OSTI Identifier:
22494052
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 42; Journal Issue: 6; Other Information: (c) 2015 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; ALGORITHMS; BIOMEDICAL RADIOGRAPHY; EYES; MEDICAL PERSONNEL; PHANTOMS; RADIOTHERAPY; SKELETON; SURGERY; SWINE; THICKNESS

Citation Formats

Corradini, N, Leick, M, Bonetti, M, and Negretti, L. SU-E-J-25: End-To-End (E2E) Testing On TomoHDA System Using a Real Pig Head for Intracranial Radiosurgery. United States: N. p., 2015. Web. doi:10.1118/1.4924112.
Corradini, N, Leick, M, Bonetti, M, & Negretti, L. SU-E-J-25: End-To-End (E2E) Testing On TomoHDA System Using a Real Pig Head for Intracranial Radiosurgery. United States. doi:10.1118/1.4924112.
Corradini, N, Leick, M, Bonetti, M, and Negretti, L. Mon . "SU-E-J-25: End-To-End (E2E) Testing On TomoHDA System Using a Real Pig Head for Intracranial Radiosurgery". United States. doi:10.1118/1.4924112.
@article{osti_22494052,
title = {SU-E-J-25: End-To-End (E2E) Testing On TomoHDA System Using a Real Pig Head for Intracranial Radiosurgery},
author = {Corradini, N and Leick, M and Bonetti, M and Negretti, L},
abstractNote = {Purpose: To determine the MVCT imaging uncertainty on the TomoHDA system for intracranial radiosurgery treatments. To determine the end-to-end (E2E) overall accuracy of the TomoHDA system for intracranial radiosurgery. Methods: A pig head was obtained from the butcher, cut coronally through the brain, and preserved in formaldehyde. The base of the head was fixed to a positioning plate allowing precise movement, i.e. translation and rotation, in all 6 axes. A repeatability test was performed on the pig head to determine uncertainty in the image bone registration algorithm. Furthermore, the test studied images with MVCT slice thicknesses of 1 and 3 mm in unison with differing scan lengths. A sensitivity test was performed to determine the registration algorithm’s ability to find the absolute position of known translations/rotations of the pig head. The algorithm’s ability to determine absolute position was compared against that of manual operators, i.e. a radiation therapist and radiation oncologist. Finally, E2E tests for intracranial radiosurgery were performed by measuring the delivered dose distributions within the pig head using Gafchromic films. Results: The repeatability test uncertainty was lowest for the MVCTs of 1-mm slice thickness, which measured less than 0.10 mm and 0.12 deg for all axes. For the sensitivity tests, the bone registration algorithm performed better than human eyes and a maximum difference of 0.3 mm and 0.4 deg was observed for the axes. E2E test results in absolute position difference measured 0.03 ± 0.21 mm in x-axis and 0.28 ± 0.18 mm in y-axis. A maximum difference of 0.32 and 0.66 mm was observed in x and y, respectively. The average peak dose difference between measured and calculated dose was 2.7 cGy or 0.4%. Conclusion: Our tests using a pig head phantom estimate the TomoHDA system to have a submillimeter overall accuracy for intracranial radiosurgery.},
doi = {10.1118/1.4924112},
journal = {Medical Physics},
number = 6,
volume = 42,
place = {United States},
year = {Mon Jun 15 00:00:00 EDT 2015},
month = {Mon Jun 15 00:00:00 EDT 2015}
}