skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Structural and degradation studies of a biocompatible Zn-L-tartrate metal–organic framework

Abstract

New anhydrous Zn-L-tratrate was synthesized under hydrothermal conditions. Crystal structure which was solved by powder X-ray diffraction data from monoclinic unit cell (I{sub 2}, a=11.7557(1), b=9.0319(1), c=5.0750(1), β=91.920(1)) consists of the three-dimensional framework where each Zn atom coordinates four tartrate ligands in distorted octahedral geometry. Due to its biocompatible components, the degradation of material was studied in aqueous media under different pH values (pH=1–7) and in the simulated body fluid (pH=7.4) performed by the measurement of the released Zn{sup 2+} concentrations at thermostatic conditions (37 °C). The results showed that under acidic conditions approximately 60% of Zn{sup 2+} is released from the investigated material after 6 h of degradation process. With the increase of the solution’s pH, the rate of degradation gradually decreases. XRD and SEM analyses indicate that in aqueous media the compound slowly disintegrates and does not undergo hydrolysis process regardless of pH. Biocompatibility of the compound and its controllable rate of degradation even in acid conditions open its potential use in the fields of bio-applications. - Graphical abstract: The degradation kinetics of Zn-L-tar MOF material in aqueous media at different pH conditions. - Highlights: • Anhydrous chiral Zn-L-tratrate was synthesized under hydrothermal conditions. • 3-D framework consistsmore » of Zn atoms, each chelating four tartrate ligands. • Degradation of material was studied in aqueous media at different pH values. • The compound disintegrates in controllable manner in aqueous solutions. • The rate compound degradation is increasing with increased acidity of solution.« less

Authors:
;  [1];  [2]; ;  [2];  [1]
  1. Ruđer Bošković Institute, Bijenička 54, 10000 Zagreb (Croatia)
  2. National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia)
Publication Date:
OSTI Identifier:
22475577
Resource Type:
Journal Article
Journal Name:
Journal of Solid State Chemistry
Additional Journal Information:
Journal Volume: 225; Other Information: Copyright (c) 2014 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0022-4596
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; AQUEOUS SOLUTIONS; BODY FLUIDS; CARBOXYLIC ACID ESTERS; CHELATING AGENTS; CHIRALITY; CONCENTRATION RATIO; HYDROLYSIS; HYDROTHERMAL SYNTHESIS; LIGANDS; MONOCLINIC LATTICES; PH VALUE; POWDERS; SCANNING ELECTRON MICROSCOPY; TAR; X-RAY DIFFRACTION; ZINC COMPOUNDS; ZINC IONS

Citation Formats

Palǒić, Ana, Puškarić, Andreas, Mazaj, Matjaž, E-mail: matjaz.mazaj@ki.si, Žunkoviǒ, Emanuela, Logar, Nataša Zabukovec, and Bronić, Josip. Structural and degradation studies of a biocompatible Zn-L-tartrate metal–organic framework. United States: N. p., 2015. Web. doi:10.1016/J.JSSC.2014.11.028.
Palǒić, Ana, Puškarić, Andreas, Mazaj, Matjaž, E-mail: matjaz.mazaj@ki.si, Žunkoviǒ, Emanuela, Logar, Nataša Zabukovec, & Bronić, Josip. Structural and degradation studies of a biocompatible Zn-L-tartrate metal–organic framework. United States. doi:10.1016/J.JSSC.2014.11.028.
Palǒić, Ana, Puškarić, Andreas, Mazaj, Matjaž, E-mail: matjaz.mazaj@ki.si, Žunkoviǒ, Emanuela, Logar, Nataša Zabukovec, and Bronić, Josip. Fri . "Structural and degradation studies of a biocompatible Zn-L-tartrate metal–organic framework". United States. doi:10.1016/J.JSSC.2014.11.028.
@article{osti_22475577,
title = {Structural and degradation studies of a biocompatible Zn-L-tartrate metal–organic framework},
author = {Palǒić, Ana and Puškarić, Andreas and Mazaj, Matjaž, E-mail: matjaz.mazaj@ki.si and Žunkoviǒ, Emanuela and Logar, Nataša Zabukovec and Bronić, Josip},
abstractNote = {New anhydrous Zn-L-tratrate was synthesized under hydrothermal conditions. Crystal structure which was solved by powder X-ray diffraction data from monoclinic unit cell (I{sub 2}, a=11.7557(1), b=9.0319(1), c=5.0750(1), β=91.920(1)) consists of the three-dimensional framework where each Zn atom coordinates four tartrate ligands in distorted octahedral geometry. Due to its biocompatible components, the degradation of material was studied in aqueous media under different pH values (pH=1–7) and in the simulated body fluid (pH=7.4) performed by the measurement of the released Zn{sup 2+} concentrations at thermostatic conditions (37 °C). The results showed that under acidic conditions approximately 60% of Zn{sup 2+} is released from the investigated material after 6 h of degradation process. With the increase of the solution’s pH, the rate of degradation gradually decreases. XRD and SEM analyses indicate that in aqueous media the compound slowly disintegrates and does not undergo hydrolysis process regardless of pH. Biocompatibility of the compound and its controllable rate of degradation even in acid conditions open its potential use in the fields of bio-applications. - Graphical abstract: The degradation kinetics of Zn-L-tar MOF material in aqueous media at different pH conditions. - Highlights: • Anhydrous chiral Zn-L-tratrate was synthesized under hydrothermal conditions. • 3-D framework consists of Zn atoms, each chelating four tartrate ligands. • Degradation of material was studied in aqueous media at different pH values. • The compound disintegrates in controllable manner in aqueous solutions. • The rate compound degradation is increasing with increased acidity of solution.},
doi = {10.1016/J.JSSC.2014.11.028},
journal = {Journal of Solid State Chemistry},
issn = {0022-4596},
number = ,
volume = 225,
place = {United States},
year = {2015},
month = {5}
}