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Title: Proton transfer in histidine-tryptophan heterodimers embedded in helium droplets

Abstract

We used cold helium droplets as nano-scale reactors to form and ionize, by electron bombardment and charge transfer, aromatic amino acid heterodimers of histidine with tryptophan, methyl-tryptophan, and indole. The molecular interaction occurring through an N–H ⋅ ⋅ ⋅ N hydrogen bond leads to a proton transfer from the indole group of tryptophan to the imidazole group of histidine in a radical cationic environment.

Authors:
; ;  [1]
  1. Department of Physics and Astronomy, University of Southern California, Los Angeles, California 90089-0484 (United States)
Publication Date:
OSTI Identifier:
22415535
Resource Type:
Journal Article
Resource Relation:
Journal Name: Journal of Chemical Physics; Journal Volume: 142; Journal Issue: 11; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; CHEMICAL BONDS; CHEMICAL REACTORS; DROPLETS; ELECTRON BEAMS; HELIUM; HISTIDINE; HYDROGEN; PROTONS; RADICALS; TRYPTOPHAN

Citation Formats

Bellina, Bruno, Merthe, Daniel J., and Kresin, Vitaly V. Proton transfer in histidine-tryptophan heterodimers embedded in helium droplets. United States: N. p., 2015. Web. doi:10.1063/1.4914902.
Bellina, Bruno, Merthe, Daniel J., & Kresin, Vitaly V. Proton transfer in histidine-tryptophan heterodimers embedded in helium droplets. United States. doi:10.1063/1.4914902.
Bellina, Bruno, Merthe, Daniel J., and Kresin, Vitaly V. Sat . "Proton transfer in histidine-tryptophan heterodimers embedded in helium droplets". United States. doi:10.1063/1.4914902.
@article{osti_22415535,
title = {Proton transfer in histidine-tryptophan heterodimers embedded in helium droplets},
author = {Bellina, Bruno and Merthe, Daniel J. and Kresin, Vitaly V.},
abstractNote = {We used cold helium droplets as nano-scale reactors to form and ionize, by electron bombardment and charge transfer, aromatic amino acid heterodimers of histidine with tryptophan, methyl-tryptophan, and indole. The molecular interaction occurring through an N–H ⋅ ⋅ ⋅ N hydrogen bond leads to a proton transfer from the indole group of tryptophan to the imidazole group of histidine in a radical cationic environment.},
doi = {10.1063/1.4914902},
journal = {Journal of Chemical Physics},
number = 11,
volume = 142,
place = {United States},
year = {Sat Mar 21 00:00:00 EDT 2015},
month = {Sat Mar 21 00:00:00 EDT 2015}
}