Adaptive beamletbased finitesize pencil beam dose calculation for independent verification of IMRT and VMAT
Abstract
Purpose: The use of sophisticated dose calculation procedure in modern radiation therapy treatment planning is inevitable in order to account for complex treatment fields created by multileaf collimators (MLCs). As a consequence, independent volumetric dose verification is time consuming, which affects the efficiency of clinical workflow. In this study, the authors present an efficient adaptive beamletbased finitesize pencil beam (ABFSPB) dose calculation algorithm that minimizes the computational procedure while preserving the accuracy. Methods: The computational time of finitesize pencil beam (FSPB) algorithm is proportional to the number of infinitesimal and identical beamlets that constitute an arbitrary field shape. In ABFSPB, dose distribution from each beamlet is mathematically modeled such that the sizes of beamlets to represent an arbitrary field shape no longer need to be infinitesimal nor identical. As a result, it is possible to represent an arbitrary field shape with combinations of different sized and minimal number of beamlets. In addition, the authors included the model parameters to consider MLC for its rounded edge and transmission. Results: Root mean square error (RMSE) between treatment planning system and conventional FSPB on a 10 × 10 cm{sup 2} square field using 10 × 10, 2.5 × 2.5, and 0.5 × 0.5more »
 Authors:
 Department of Radiation Oncology, University of Florida, Gainesville, Florida 326100385 (United States)
 Publication Date:
 OSTI Identifier:
 22413513
 Resource Type:
 Journal Article
 Resource Relation:
 Journal Name: Medical Physics; Journal Volume: 42; Journal Issue: 4; Other Information: (c) 2015 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
 Country of Publication:
 United States
 Language:
 English
 Subject:
 62 RADIOLOGY AND NUCLEAR MEDICINE; 60 APPLIED LIFE SCIENCES; ACCURACY; ALGORITHMS; CALCULATION METHODS; COLLIMATORS; PLANNING; RADIATION DOSE DISTRIBUTIONS; RADIATION DOSES; RADIOTHERAPY; VERIFICATION
Citation Formats
Park, Justin C., Li, Jonathan G., Arhjoul, Lahcen, Yan, Guanghua, Lu, Bo, Fan, Qiyong, and Liu, Chihray, Email: liucr@ufl.edu. Adaptive beamletbased finitesize pencil beam dose calculation for independent verification of IMRT and VMAT. United States: N. p., 2015.
Web. doi:10.1118/1.4914858.
Park, Justin C., Li, Jonathan G., Arhjoul, Lahcen, Yan, Guanghua, Lu, Bo, Fan, Qiyong, & Liu, Chihray, Email: liucr@ufl.edu. Adaptive beamletbased finitesize pencil beam dose calculation for independent verification of IMRT and VMAT. United States. doi:10.1118/1.4914858.
Park, Justin C., Li, Jonathan G., Arhjoul, Lahcen, Yan, Guanghua, Lu, Bo, Fan, Qiyong, and Liu, Chihray, Email: liucr@ufl.edu. Wed .
"Adaptive beamletbased finitesize pencil beam dose calculation for independent verification of IMRT and VMAT". United States.
doi:10.1118/1.4914858.
@article{osti_22413513,
title = {Adaptive beamletbased finitesize pencil beam dose calculation for independent verification of IMRT and VMAT},
author = {Park, Justin C. and Li, Jonathan G. and Arhjoul, Lahcen and Yan, Guanghua and Lu, Bo and Fan, Qiyong and Liu, Chihray, Email: liucr@ufl.edu},
abstractNote = {Purpose: The use of sophisticated dose calculation procedure in modern radiation therapy treatment planning is inevitable in order to account for complex treatment fields created by multileaf collimators (MLCs). As a consequence, independent volumetric dose verification is time consuming, which affects the efficiency of clinical workflow. In this study, the authors present an efficient adaptive beamletbased finitesize pencil beam (ABFSPB) dose calculation algorithm that minimizes the computational procedure while preserving the accuracy. Methods: The computational time of finitesize pencil beam (FSPB) algorithm is proportional to the number of infinitesimal and identical beamlets that constitute an arbitrary field shape. In ABFSPB, dose distribution from each beamlet is mathematically modeled such that the sizes of beamlets to represent an arbitrary field shape no longer need to be infinitesimal nor identical. As a result, it is possible to represent an arbitrary field shape with combinations of different sized and minimal number of beamlets. In addition, the authors included the model parameters to consider MLC for its rounded edge and transmission. Results: Root mean square error (RMSE) between treatment planning system and conventional FSPB on a 10 × 10 cm{sup 2} square field using 10 × 10, 2.5 × 2.5, and 0.5 × 0.5 cm{sup 2} beamlet sizes were 4.90%, 3.19%, and 2.87%, respectively, compared with RMSE of 1.10%, 1.11%, and 1.14% for ABFSPB. This finding holds true for a larger square field size of 25 × 25 cm{sup 2}, where RMSE for 25 × 25, 2.5 × 2.5, and 0.5 × 0.5 cm{sup 2} beamlet sizes were 5.41%, 4.76%, and 3.54% in FSPB, respectively, compared with RMSE of 0.86%, 0.83%, and 0.88% for ABFSPB. It was found that ABFSPB could successfully account for the MLC transmissions without major discrepancy. The algorithm was also graphical processing unit (GPU) compatible to maximize its computational speed. For an intensity modulated radiation therapy (∼12 segments) and a volumetric modulated arc therapy fields (∼90 control points) with a 3D grid size of 2.0 × 2.0 × 2.0 mm{sup 3}, dose was computed within 3–5 and 10–15 s timeframe, respectively. Conclusions: The authors have developed an efficient adaptive beamletbased pencil beam dose calculation algorithm. The fast computation nature along with GPU compatibility has shown better performance than conventional FSPB. This enables the implementation of ABFSPB in the clinical environment for independent volumetric dose verification.},
doi = {10.1118/1.4914858},
journal = {Medical Physics},
number = 4,
volume = 42,
place = {United States},
year = {Wed Apr 15 00:00:00 EDT 2015},
month = {Wed Apr 15 00:00:00 EDT 2015}
}

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SUFT428: An OptimizationBased Commissioning Tool for Finite Size Pencil Beam Dose Calculations
Purpose: Finite size pencil beam (FSPB) algorithms are commonly used to precalculate the beamlet dose distribution for IMRT treatment planning. FSPB commissioning, which usually requires fine tuning of the FSPB kernel parameters, is crucial to the dose calculation accuracy and hence the plan quality. Yet due to the large number of beamlets, FSPB commissioning could be very tedious. This abstract reports an optimizationbased FSPB commissioning tool we have developed in MatLab to facilitate the commissioning. Methods: A FSPB dose kernel generally contains two types of parameters: the profile parameters determining the dose kernel shape, and a 2D scaling factors accountingmore »