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Title: Near-field acoustic microbead trapping as remote anchor for single particle manipulation

Abstract

We recently proposed an analytical model of a two-dimensional acoustic trapping of polystyrene beads in the ray acoustics regime, where a bead diameter is larger than the wavelength used. As its experimental validation, this paper demonstrates the transverse (or lateral) trapping of individual polystyrene beads in the near field of focused ultrasound. A 100 μm bead is immobilized on the central beam axis by a focused sound beam from a 30 MHz single element lithium niobate transducer, after being laterally displaced through hundreds of micrometers. Maximum displacement, a longest lateral distance at which a trapped bead can be directed towards the central axis, is thus measured over a discrete frequency range from 24 MHz to 36 MHz. The displacement data are found to be between 323.7 μm and 470.2 μm, depending on the transducer's driving frequency and input voltage amplitude. The experimental results are compared with their corresponding model values, and their relative errors lie between 0.9% and 3.9%. The results suggest that this remote maneuvering technique may be employed to manipulate individual cells through solid microbeads, provoking certain cellular reactions to localized mechanical disturbance without direct contact.

Authors:
 [1]; ; ; ;  [2]
  1. Department of Information and Communication Engineering, Daegu Gyeongbuk Institute of Science and Technology, Daegu (Korea, Republic of)
  2. Department of Electronic Engineering, Kwangwoon University, Seoul (Korea, Republic of)
Publication Date:
OSTI Identifier:
22399024
Resource Type:
Journal Article
Journal Name:
Applied Physics Letters
Additional Journal Information:
Journal Volume: 106; Journal Issue: 18; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0003-6951
Country of Publication:
United States
Language:
English
Subject:
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; ACOUSTICS; AMPLITUDES; COMPARATIVE EVALUATIONS; DISTANCE; ELECTRIC POTENTIAL; LITHIUM COMPOUNDS; MHZ RANGE; NIOBATES; PARTICLES; POLYSTYRENE; SOLIDS; SOUND WAVES; TRANSDUCERS; TRAPPING; TWO-DIMENSIONAL SYSTEMS

Citation Formats

Hwang, Jae Youn, Cheon, Dong Young, Shin, Hyunjune, Kim, Hyun Bin, and Lee, Jungwoo, E-mail: jwlee@kw.ac.kr. Near-field acoustic microbead trapping as remote anchor for single particle manipulation. United States: N. p., 2015. Web. doi:10.1063/1.4919802.
Hwang, Jae Youn, Cheon, Dong Young, Shin, Hyunjune, Kim, Hyun Bin, & Lee, Jungwoo, E-mail: jwlee@kw.ac.kr. Near-field acoustic microbead trapping as remote anchor for single particle manipulation. United States. doi:10.1063/1.4919802.
Hwang, Jae Youn, Cheon, Dong Young, Shin, Hyunjune, Kim, Hyun Bin, and Lee, Jungwoo, E-mail: jwlee@kw.ac.kr. Mon . "Near-field acoustic microbead trapping as remote anchor for single particle manipulation". United States. doi:10.1063/1.4919802.
@article{osti_22399024,
title = {Near-field acoustic microbead trapping as remote anchor for single particle manipulation},
author = {Hwang, Jae Youn and Cheon, Dong Young and Shin, Hyunjune and Kim, Hyun Bin and Lee, Jungwoo, E-mail: jwlee@kw.ac.kr},
abstractNote = {We recently proposed an analytical model of a two-dimensional acoustic trapping of polystyrene beads in the ray acoustics regime, where a bead diameter is larger than the wavelength used. As its experimental validation, this paper demonstrates the transverse (or lateral) trapping of individual polystyrene beads in the near field of focused ultrasound. A 100 μm bead is immobilized on the central beam axis by a focused sound beam from a 30 MHz single element lithium niobate transducer, after being laterally displaced through hundreds of micrometers. Maximum displacement, a longest lateral distance at which a trapped bead can be directed towards the central axis, is thus measured over a discrete frequency range from 24 MHz to 36 MHz. The displacement data are found to be between 323.7 μm and 470.2 μm, depending on the transducer's driving frequency and input voltage amplitude. The experimental results are compared with their corresponding model values, and their relative errors lie between 0.9% and 3.9%. The results suggest that this remote maneuvering technique may be employed to manipulate individual cells through solid microbeads, provoking certain cellular reactions to localized mechanical disturbance without direct contact.},
doi = {10.1063/1.4919802},
journal = {Applied Physics Letters},
issn = {0003-6951},
number = 18,
volume = 106,
place = {United States},
year = {2015},
month = {5}
}