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Title: Synthesis of superparamagnetic silica-coated magnetite nanoparticles for biomedical applications

Abstract

Multifunctional superparamagnetic iron oxide nanoparticles (SPIONs) coated with silica are widely researched for biomedical applications such as magnetic resonance imaging, tissue repair, cell separation, hyperthermia, drug delivery, etc. In this article synthesis of magnetite (Fe{sub 3}O{sub 4}) nanoparticles and their coating with SiO{sub 2} is reported. Fe{sub 3}O{sub 4} nanoparticles were synthesized by chemical co-precipitation and it was coated with silica by hydrolysis and condensation of tetraethylorthosilicate. XRD, FTIR, TEM and VSM techniques were used to characterize bare and coated nanoparticles. Results indicated that the average size of SPIONS was 8.4 nm. X-ray diffraction patterns of silica coated SPIONS were identical to that of SPIONS confirming the inner spinal structure of SPIONS. FTIR results confirmed the binding of silica with the magnetite and the formation of the silica shell around the magnetite core. Magnetic properties of SPIONS and silica coated SPIONS are determined by VSM. They are superparamagnetic. The major conclusion drawn from this study is that the synthesis route yields stable, non-aggregated magnetite-silica core-shell nanostructures with tailored morphology and excellent magnetic properties.

Authors:
;  [1]
  1. School of Physics and Materials Science, Thapar University, Patiala-147004 (India)
Publication Date:
OSTI Identifier:
22391705
Resource Type:
Journal Article
Journal Name:
AIP Conference Proceedings
Additional Journal Information:
Journal Volume: 1661; Journal Issue: 1; Conference: ICCMP 2014: International Conference on Condensed Matter Physics 2014, Shimla (India), 4-6 Nov 2014; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-243X
Country of Publication:
United States
Language:
English
Subject:
77 NANOSCIENCE AND NANOTECHNOLOGY; COPRECIPITATION; FERRITES; FOURIER TRANSFORMATION; HYPERTHERMIA; INFRARED SPECTRA; IRON OXIDES; MAGNETIC PROPERTIES; MAGNETITE; MORPHOLOGY; NANOPARTICLES; NANOSTRUCTURES; NMR IMAGING; SILICA; SILICON OXIDES; SUPERPARAMAGNETISM; SYNTHESIS; TRANSMISSION ELECTRON MICROSCOPY; VIBRATING SAMPLE MAGNETOMETERS; X-RAY DIFFRACTION

Citation Formats

Kaur, Navjot, E-mail: navjot.dhindsa2989@gmail.com, and Chudasama, Bhupendra, E-mail: bnchudasama@gmail.com. Synthesis of superparamagnetic silica-coated magnetite nanoparticles for biomedical applications. United States: N. p., 2015. Web. doi:10.1063/1.4915382.
Kaur, Navjot, E-mail: navjot.dhindsa2989@gmail.com, & Chudasama, Bhupendra, E-mail: bnchudasama@gmail.com. Synthesis of superparamagnetic silica-coated magnetite nanoparticles for biomedical applications. United States. doi:10.1063/1.4915382.
Kaur, Navjot, E-mail: navjot.dhindsa2989@gmail.com, and Chudasama, Bhupendra, E-mail: bnchudasama@gmail.com. Fri . "Synthesis of superparamagnetic silica-coated magnetite nanoparticles for biomedical applications". United States. doi:10.1063/1.4915382.
@article{osti_22391705,
title = {Synthesis of superparamagnetic silica-coated magnetite nanoparticles for biomedical applications},
author = {Kaur, Navjot, E-mail: navjot.dhindsa2989@gmail.com and Chudasama, Bhupendra, E-mail: bnchudasama@gmail.com},
abstractNote = {Multifunctional superparamagnetic iron oxide nanoparticles (SPIONs) coated with silica are widely researched for biomedical applications such as magnetic resonance imaging, tissue repair, cell separation, hyperthermia, drug delivery, etc. In this article synthesis of magnetite (Fe{sub 3}O{sub 4}) nanoparticles and their coating with SiO{sub 2} is reported. Fe{sub 3}O{sub 4} nanoparticles were synthesized by chemical co-precipitation and it was coated with silica by hydrolysis and condensation of tetraethylorthosilicate. XRD, FTIR, TEM and VSM techniques were used to characterize bare and coated nanoparticles. Results indicated that the average size of SPIONS was 8.4 nm. X-ray diffraction patterns of silica coated SPIONS were identical to that of SPIONS confirming the inner spinal structure of SPIONS. FTIR results confirmed the binding of silica with the magnetite and the formation of the silica shell around the magnetite core. Magnetic properties of SPIONS and silica coated SPIONS are determined by VSM. They are superparamagnetic. The major conclusion drawn from this study is that the synthesis route yields stable, non-aggregated magnetite-silica core-shell nanostructures with tailored morphology and excellent magnetic properties.},
doi = {10.1063/1.4915382},
journal = {AIP Conference Proceedings},
issn = {0094-243X},
number = 1,
volume = 1661,
place = {United States},
year = {2015},
month = {5}
}