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Title: Laboratory-size three-dimensional x-ray microscope with Wolter type I mirror optics and an electron-impact water window x-ray source

Abstract

We constructed a laboratory-size three-dimensional water window x-ray microscope that combines wide-field transmission x-ray microscopy with tomographic reconstruction techniques, and observed bio-medical samples to evaluate its applicability to life science research fields. It consists of a condenser and an objective grazing incidence Wolter type I mirror, an electron-impact type oxygen Kα x-ray source, and a back-illuminated CCD for x-ray imaging. A spatial resolution limit of around 1.0 line pairs per micrometer was obtained for two-dimensional transmission images, and 1-μm scale three-dimensional fine structures were resolved.

Authors:
 [1];  [2]; ; ;  [1];  [1];  [2]; ; ;  [3]
  1. Hamamatsu Photonics K.K., 5000 Hirakuchi, Hamakita-ku, Hamamatsu-City, 434-8601 (Japan)
  2. (Japan)
  3. Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904 (Japan)
Publication Date:
OSTI Identifier:
22314452
Resource Type:
Journal Article
Journal Name:
Review of Scientific Instruments
Additional Journal Information:
Journal Volume: 85; Journal Issue: 9; Other Information: (c) 2014 Author(s); Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0034-6748
Country of Publication:
United States
Language:
English
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; CHARGE-COUPLED DEVICES; COMPRESSORS; FINE STRUCTURE; GRAZING INCIDENCE TOMOGRAPHY; IMAGES; MICROSCOPES; MICROSCOPY; MIRRORS; OPTICS; OXYGEN; SPATIAL RESOLUTION; TELESCOPES; WATER; X RADIATION; X-RAY SOURCES

Citation Formats

Ohsuka, Shinji, E-mail: ohsuka@crl.hpk.co.jp, The Graduate School for the Creation of New Photonics Industries, 1955-1 Kurematsu-cho, Nishi-ku, Hamamatsu-City, 431-1202, Ohba, Akira, Onoda, Shinobu, Nakamoto, Katsuhiro, Nakano, Tomoyasu, Ray-Focus Co. Ltd., 6009 Shinpara, Hamakita-ku, Hamamatsu-City, 434-0003, Miyoshi, Motosuke, Soda, Keita, and Hamakubo, Takao. Laboratory-size three-dimensional x-ray microscope with Wolter type I mirror optics and an electron-impact water window x-ray source. United States: N. p., 2014. Web. doi:10.1063/1.4894468.
Ohsuka, Shinji, E-mail: ohsuka@crl.hpk.co.jp, The Graduate School for the Creation of New Photonics Industries, 1955-1 Kurematsu-cho, Nishi-ku, Hamamatsu-City, 431-1202, Ohba, Akira, Onoda, Shinobu, Nakamoto, Katsuhiro, Nakano, Tomoyasu, Ray-Focus Co. Ltd., 6009 Shinpara, Hamakita-ku, Hamamatsu-City, 434-0003, Miyoshi, Motosuke, Soda, Keita, & Hamakubo, Takao. Laboratory-size three-dimensional x-ray microscope with Wolter type I mirror optics and an electron-impact water window x-ray source. United States. doi:10.1063/1.4894468.
Ohsuka, Shinji, E-mail: ohsuka@crl.hpk.co.jp, The Graduate School for the Creation of New Photonics Industries, 1955-1 Kurematsu-cho, Nishi-ku, Hamamatsu-City, 431-1202, Ohba, Akira, Onoda, Shinobu, Nakamoto, Katsuhiro, Nakano, Tomoyasu, Ray-Focus Co. Ltd., 6009 Shinpara, Hamakita-ku, Hamamatsu-City, 434-0003, Miyoshi, Motosuke, Soda, Keita, and Hamakubo, Takao. Mon . "Laboratory-size three-dimensional x-ray microscope with Wolter type I mirror optics and an electron-impact water window x-ray source". United States. doi:10.1063/1.4894468.
@article{osti_22314452,
title = {Laboratory-size three-dimensional x-ray microscope with Wolter type I mirror optics and an electron-impact water window x-ray source},
author = {Ohsuka, Shinji, E-mail: ohsuka@crl.hpk.co.jp and The Graduate School for the Creation of New Photonics Industries, 1955-1 Kurematsu-cho, Nishi-ku, Hamamatsu-City, 431-1202 and Ohba, Akira and Onoda, Shinobu and Nakamoto, Katsuhiro and Nakano, Tomoyasu and Ray-Focus Co. Ltd., 6009 Shinpara, Hamakita-ku, Hamamatsu-City, 434-0003 and Miyoshi, Motosuke and Soda, Keita and Hamakubo, Takao},
abstractNote = {We constructed a laboratory-size three-dimensional water window x-ray microscope that combines wide-field transmission x-ray microscopy with tomographic reconstruction techniques, and observed bio-medical samples to evaluate its applicability to life science research fields. It consists of a condenser and an objective grazing incidence Wolter type I mirror, an electron-impact type oxygen Kα x-ray source, and a back-illuminated CCD for x-ray imaging. A spatial resolution limit of around 1.0 line pairs per micrometer was obtained for two-dimensional transmission images, and 1-μm scale three-dimensional fine structures were resolved.},
doi = {10.1063/1.4894468},
journal = {Review of Scientific Instruments},
issn = {0034-6748},
number = 9,
volume = 85,
place = {United States},
year = {2014},
month = {9}
}