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Method and apparatus for ion mobility separations utilizing alternating current waveforms

Patent ·
OSTI ID:2222343

Methods and apparatuses for ion manipulations, including ion trapping, transfer, and mobility separations, using traveling waves (TW) formed by continuous alternating current (AC) are disclosed. An apparatus for ion manipulation includes a surface to which are coupled a first plurality of continuous electrodes and a second plurality of segmented electrodes. The second plurality of segmented electrodes is arranged in longitudinal sets between or adjacent to the first plurality of electrodes. An RF voltage applied to adjacent electrodes of the first plurality of electrodes is phase shifted by approximately 180° to confine ions within the apparatus. An AC voltage waveform applied to adjacent electrodes within a longitudinal set of the second plurality of segmented electrodes is phase shifted on the adjacent electrodes by 1°-359° to move ions longitudinally through the apparatus for separation.

Research Organization:
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Sponsoring Organization:
USDOE; National Institutes of Health (NIH)
DOE Contract Number:
AC05-76RL01830
Assignee:
Battelle Memorial Institute (Richland, WA)
Patent Number(s):
11,761,925
Application Number:
17/557,690
OSTI ID:
2222343
Country of Publication:
United States
Language:
English

References (10)

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A new nonlevitated mode of traveling wave toner transport journal January 1991
Lipid and Glycolipid Isomer Analyses Using Ultra-High Resolution Ion Mobility Spectrometry Separations journal January 2017
Characterization of Ion Dynamics in Structures for Lossless Ion Manipulations journal September 2014
Characterization of Traveling Wave Ion Mobility Separations in Structures for Lossless Ion Manipulations journal October 2015