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Title: Safety of Chemotherapeutic Infusion or Chemoembolization for Hepatocellular Carcinoma Supplied Exclusively by the Cystic Artery

Abstract

Purpose: This study was designed to evaluate the safety of chemotherapeutic infusion or chemoembolization by way of the cystic artery in patients with hepatocellular carcinoma (HCC) supplied exclusively by the cystic artery. Methods: Between Jan 2002 and Dec 2011, we performed chemotherapeutic infusion or chemoembolization using iodized oil for the treatment of 27 patients with HCC supplied exclusively by the cystic artery. Computed tomography (CT) scans, digital subtraction angiograms, and medical records were retrospectively reviewed by consensus. Results: The cystic artery originated from the main right hepatic artery in 24 (89 %) patients, from the right anterior hepatic artery in 2 (7 %) patients, and from the left hepatic artery in 1 (4 %) patient. Selective catheterization of the cystic artery was achieved in all patients. Superselection of tumor-feeding vessels from the cystic artery was achieved in 7 patients (26 %). Chemotherapeutic infusion was performed in 18 patients (67 %), and chemoembolization was performed in 9 patients (33 %). There were no major complications and only 2 minor complications, including vasovagal syncope and nausea with vomiting. Individual tumor response supplied exclusively by the cystic artery at the follow-up enhanced CT scan were complete response (n = 16), partial response (nmore » = 3), and stable disease (n = 8). Conclusion: HCC supplied exclusively by the cystic artery can be safely treated without severe complications by chemotherapeutic infusion or chemoembolization using iodized oil through the cystic artery.« less

Authors:
; ; ;
Publication Date:
OSTI Identifier:
22208020
Resource Type:
Journal Article
Journal Name:
Cardiovascular and Interventional Radiology
Additional Journal Information:
Journal Volume: 36; Journal Issue: 5; Other Information: Copyright (c) 2013 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0174-1551
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ARTERIES; COMPUTERIZED TOMOGRAPHY; HEPATOMAS; INFUSION; LIVER; MEDICAL RECORDS; NAUSEA; PATIENTS; REVIEWS; VASCULAR DISEASES; VOMITING

Citation Formats

Kang, Beomsik, Kim, Hyo-Cheol, Chung, Jin Wook, E-mail: chungjw@snu.ac.kr, Hur, Saebeom, Joo, Seung-Moon, Jae, Hwan Jun, E-mail: jhj@radiol.snu.ac.kr, and Park, Jae Hyung, E-mail: parkjh4803@gmail.com. Safety of Chemotherapeutic Infusion or Chemoembolization for Hepatocellular Carcinoma Supplied Exclusively by the Cystic Artery. United States: N. p., 2013. Web. doi:10.1007/S00270-012-0542-6.
Kang, Beomsik, Kim, Hyo-Cheol, Chung, Jin Wook, E-mail: chungjw@snu.ac.kr, Hur, Saebeom, Joo, Seung-Moon, Jae, Hwan Jun, E-mail: jhj@radiol.snu.ac.kr, & Park, Jae Hyung, E-mail: parkjh4803@gmail.com. Safety of Chemotherapeutic Infusion or Chemoembolization for Hepatocellular Carcinoma Supplied Exclusively by the Cystic Artery. United States. https://doi.org/10.1007/S00270-012-0542-6
Kang, Beomsik, Kim, Hyo-Cheol, Chung, Jin Wook, E-mail: chungjw@snu.ac.kr, Hur, Saebeom, Joo, Seung-Moon, Jae, Hwan Jun, E-mail: jhj@radiol.snu.ac.kr, and Park, Jae Hyung, E-mail: parkjh4803@gmail.com. 2013. "Safety of Chemotherapeutic Infusion or Chemoembolization for Hepatocellular Carcinoma Supplied Exclusively by the Cystic Artery". United States. https://doi.org/10.1007/S00270-012-0542-6.
@article{osti_22208020,
title = {Safety of Chemotherapeutic Infusion or Chemoembolization for Hepatocellular Carcinoma Supplied Exclusively by the Cystic Artery},
author = {Kang, Beomsik and Kim, Hyo-Cheol and Chung, Jin Wook, E-mail: chungjw@snu.ac.kr and Hur, Saebeom and Joo, Seung-Moon and Jae, Hwan Jun, E-mail: jhj@radiol.snu.ac.kr and Park, Jae Hyung, E-mail: parkjh4803@gmail.com},
abstractNote = {Purpose: This study was designed to evaluate the safety of chemotherapeutic infusion or chemoembolization by way of the cystic artery in patients with hepatocellular carcinoma (HCC) supplied exclusively by the cystic artery. Methods: Between Jan 2002 and Dec 2011, we performed chemotherapeutic infusion or chemoembolization using iodized oil for the treatment of 27 patients with HCC supplied exclusively by the cystic artery. Computed tomography (CT) scans, digital subtraction angiograms, and medical records were retrospectively reviewed by consensus. Results: The cystic artery originated from the main right hepatic artery in 24 (89 %) patients, from the right anterior hepatic artery in 2 (7 %) patients, and from the left hepatic artery in 1 (4 %) patient. Selective catheterization of the cystic artery was achieved in all patients. Superselection of tumor-feeding vessels from the cystic artery was achieved in 7 patients (26 %). Chemotherapeutic infusion was performed in 18 patients (67 %), and chemoembolization was performed in 9 patients (33 %). There were no major complications and only 2 minor complications, including vasovagal syncope and nausea with vomiting. Individual tumor response supplied exclusively by the cystic artery at the follow-up enhanced CT scan were complete response (n = 16), partial response (n = 3), and stable disease (n = 8). Conclusion: HCC supplied exclusively by the cystic artery can be safely treated without severe complications by chemotherapeutic infusion or chemoembolization using iodized oil through the cystic artery.},
doi = {10.1007/S00270-012-0542-6},
url = {https://www.osti.gov/biblio/22208020}, journal = {Cardiovascular and Interventional Radiology},
issn = {0174-1551},
number = 5,
volume = 36,
place = {United States},
year = {Tue Oct 15 00:00:00 EDT 2013},
month = {Tue Oct 15 00:00:00 EDT 2013}
}