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Title: Y90-Radioembolization of Lung Metastases via the Bronchial Artery: A Report of 2 Cases

Abstract

We report successful Y90-radioembolization of the lung applying Y90-resin microspheres via the bronchial artery in two patients with diffuse colorectal and renal cancer metastases, respectively. The deposition of radioactive Y90-resin-microspheres was technically feasible and resulted in a reasonable absorbed dose in the tumors. However, open questions remain regarding dosimetry and safe dose exposure to the lung. The technique warrants thorough investigation before clinical use. A Phase I trial to evaluate safety and preliminary efficacy is under preparation.

Authors:
; ;  [1]
  1. Universitaetsklinikum Magdeburg AoeR, Klinik fuer Radiologie und Nuklearmedizin (Germany)
Publication Date:
OSTI Identifier:
22207958
Resource Type:
Journal Article
Journal Name:
Cardiovascular and Interventional Radiology
Additional Journal Information:
Journal Volume: 36; Journal Issue: 6; Other Information: Copyright (c) 2013 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0174-1551
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ABSORBED RADIATION DOSES; ARTERIES; DOSIMETRY; KIDNEYS; LUNGS; METASTASES; MICROSPHERES; NEOPLASMS; PATIENTS; YTTRIUM 90; RADIOEMBOLIZATION

Citation Formats

Ricke, Jens, Grosser, Oliver, and Amthauer, Holger. Y90-Radioembolization of Lung Metastases via the Bronchial Artery: A Report of 2 Cases. United States: N. p., 2013. Web. doi:10.1007/S00270-013-0690-3.
Ricke, Jens, Grosser, Oliver, & Amthauer, Holger. Y90-Radioembolization of Lung Metastases via the Bronchial Artery: A Report of 2 Cases. United States. https://doi.org/10.1007/S00270-013-0690-3
Ricke, Jens, Grosser, Oliver, and Amthauer, Holger. 2013. "Y90-Radioembolization of Lung Metastases via the Bronchial Artery: A Report of 2 Cases". United States. https://doi.org/10.1007/S00270-013-0690-3.
@article{osti_22207958,
title = {Y90-Radioembolization of Lung Metastases via the Bronchial Artery: A Report of 2 Cases},
author = {Ricke, Jens and Grosser, Oliver and Amthauer, Holger},
abstractNote = {We report successful Y90-radioembolization of the lung applying Y90-resin microspheres via the bronchial artery in two patients with diffuse colorectal and renal cancer metastases, respectively. The deposition of radioactive Y90-resin-microspheres was technically feasible and resulted in a reasonable absorbed dose in the tumors. However, open questions remain regarding dosimetry and safe dose exposure to the lung. The technique warrants thorough investigation before clinical use. A Phase I trial to evaluate safety and preliminary efficacy is under preparation.},
doi = {10.1007/S00270-013-0690-3},
url = {https://www.osti.gov/biblio/22207958}, journal = {Cardiovascular and Interventional Radiology},
issn = {0174-1551},
number = 6,
volume = 36,
place = {United States},
year = {Sun Dec 15 00:00:00 EST 2013},
month = {Sun Dec 15 00:00:00 EST 2013}
}