Microwave Ablation of Pulmonary Malignancies Using a Novel High-energy Antenna System

Little, Mark W.; Chung, Daniel; Boardman, Philip; Gleeson, Fergus V.

doi:10.1007/S00270-012-0465-2

Title: Microwave Ablation of Pulmonary Malignancies Using a Novel High-energy Antenna System

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Abstract

To evaluate the technical success, safety, and imaging follow-up of malignant pulmonary nodules treated with a novel high-energy percutaneous microwave ablation (MWA) system. Between July 2010 and September 2011, a total of 23 patients, 12 men, mean age 68 (range 30-87) years with 29 pulmonary malignancies of median diameter 19 (range 8-57) mm, underwent computed tomography (CT)-guided MWA with a 16G microwave needle antenna enabling power up to 180 W. Technical success was defined as needle placement in the intended lesion without death or serious injury. Adequacy of ablation was assessed at 24 h on contrast-enhanced CT. Circumferential solid or ground glass opacification >5 mm was used to define an ideal ablation. Local tumor recurrence was assessed at 1, 3, and 6 months after ablation on contrast-enhanced CT. MWA was technically successful in 93 % (n = 27). Mean ablation duration was 3.6 (range 1-9) min. Ten patients (43 %) developed a pneumothorax as a result of the MWA; only 3 (13 %) required placement of a chest drain. Thirty-day mortality rate was 0 %. The mean hospital stay was 1.5 (range 1-7) days. A total of 22 lesions (75 %) were surrounded by {>=}5 mm ground glass or solidmore »« less

Authors:: Little, Mark W.; Chung, Daniel; Boardman, Philip; Gleeson, Fergus V.

Publication Date:: Mon Apr 15 00:00:00 EDT 2013

OSTI Identifier:: 22156366

Resource Type:: Journal Article

Journal Name:: Cardiovascular and Interventional Radiology

Additional Journal Information:: Journal Volume: 36; Journal Issue: 2; Other Information: Copyright (c) 2013 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); Article Copyright (c) 2012 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0174-1551

Country of Publication:: United States

Language:: English

Subject:: 62 RADIOLOGY AND NUCLEAR MEDICINE; ABLATION; ANTENNAS; CHEST; CONTROL; DEATH; GLASS; INJURIES; MICROWAVE RADIATION; MORTALITY; PATIENTS; SAFETY; SOLIDS

Citation Formats


                    Little, Mark W., Chung, Daniel, Boardman, Philip, Gleeson, Fergus V., and Anderson, Ewan M., E-mail: ewan.anderson@ouh.nhs.uk. Microwave Ablation of Pulmonary Malignancies Using a Novel High-energy Antenna System.  United States: N. p., 2013. 
        Web.  doi:10.1007/S00270-012-0465-2.

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                    Little, Mark W., Chung, Daniel, Boardman, Philip, Gleeson, Fergus V., & Anderson, Ewan M., E-mail: ewan.anderson@ouh.nhs.uk. Microwave Ablation of Pulmonary Malignancies Using a Novel High-energy Antenna System.  United States.  https://doi.org/10.1007/S00270-012-0465-2

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                    Little, Mark W., Chung, Daniel, Boardman, Philip, Gleeson, Fergus V., and Anderson, Ewan M., E-mail: ewan.anderson@ouh.nhs.uk. 2013.  
        "Microwave Ablation of Pulmonary Malignancies Using a Novel High-energy Antenna System".  United States.  https://doi.org/10.1007/S00270-012-0465-2.

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@article{osti_22156366,

  title        = {Microwave Ablation of Pulmonary Malignancies Using a Novel High-energy Antenna System},

  author       = {Little, Mark W. and Chung, Daniel and Boardman, Philip and Gleeson, Fergus V. and Anderson, Ewan M., E-mail: ewan.anderson@ouh.nhs.uk},

  abstractNote = {To evaluate the technical success, safety, and imaging follow-up of malignant pulmonary nodules treated with a novel high-energy percutaneous microwave ablation (MWA) system. Between July 2010 and September 2011, a total of 23 patients, 12 men, mean age 68 (range 30-87) years with 29 pulmonary malignancies of median diameter 19 (range 8-57) mm, underwent computed tomography (CT)-guided MWA with a 16G microwave needle antenna enabling power up to 180 W. Technical success was defined as needle placement in the intended lesion without death or serious injury. Adequacy of ablation was assessed at 24 h on contrast-enhanced CT. Circumferential solid or ground glass opacification >5 mm was used to define an ideal ablation. Local tumor recurrence was assessed at 1, 3, and 6 months after ablation on contrast-enhanced CT. MWA was technically successful in 93 % (n = 27). Mean ablation duration was 3.6 (range 1-9) min. Ten patients (43 %) developed a pneumothorax as a result of the MWA; only 3 (13 %) required placement of a chest drain. Thirty-day mortality rate was 0 %. The mean hospital stay was 1.5 (range 1-7) days. A total of 22 lesions (75 %) were surrounded by {>=}5 mm ground glass or solid opacification after the procedure. At a median follow-up of 6 months, local recurrence was identified in 3 out of 26 lesions, giving a local control rate of 88 %. MWA using a high-power antenna of pulmonary malignancies is safe, technically achievable, and enables fast ablation times.},

  doi          = {10.1007/S00270-012-0465-2},

  url          = {https://www.osti.gov/biblio/22156366},
  journal      = {Cardiovascular and Interventional Radiology},

  issn         = {0174-1551},

  number       = 2,

  volume       = 36,

  place        = {United States},

  year         = {Mon Apr 15 00:00:00 EDT 2013},

  month        = {Mon Apr 15 00:00:00 EDT 2013}

}

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