Surgical Management of Early-Stage Non-small Cell Lung Carcinoma and the Present and Future Roles of Adjuvant Therapy: A Review for the Radiation Oncologist
Journal Article
·
· International Journal of Radiation Oncology, Biology and Physics
- Department of Emergency Medicine, Ben Taub General Hospital, Houston, TX (United States)
- Division of Thoracic Surgery, Department of Surgery, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago, Illinois (United States)
- Department of Radiation Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts (United States)
- Department of Radiation Oncology, Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania (United States)
- Department of Medical Oncology, Penn State Hershey Cancer Institute, Hershey, Pennsylvania (United States)
- Division of Radiation Oncology, Penn State Hershey Cancer Institute, Hershey, Pennsylvania (United States)
We review the evidence for optimal surgical management and adjuvant therapy for patients with stages I and II non-small cell lung cancer (NSCLC) along with factors associated with increased risks of recurrence. Based on the current evidence, we recommend optimal use of mediastinal lymph node dissection, adjuvant chemotherapy, and post-operative radiation therapy, and make suggestions for areas to explore in future prospective randomized clinical trials.
- OSTI ID:
- 22149657
- Journal Information:
- International Journal of Radiation Oncology, Biology and Physics, Vol. 84, Issue 5; Other Information: Copyright (c) 2012 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA); ISSN 0360-3016
- Country of Publication:
- United States
- Language:
- English
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