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Title: Comparison of external beam treatment techniques for T1-2, N0, M0 glottic cancers

Abstract

The purpose of this study was to compare 4 different external beam radiation therapy treatment techniques for the treatment of T1-2, N0, M0 glottic cancers: traditional lateral beams with wedges (3D), 5-field intensity-modulated radiation therapy (IMRT), volumetric modulated arc therapy (VMAT), and proton therapy. Treatment plans in each technique were created for 10 patients using consistent planning parameters. The photon treatment plans were optimized using Philips Pinnacle{sub 3} v.9 and the IMRT and VMAT plans used the Direct Machine Parameter Optimization algorithm. The proton treatment plans were optimized using Varian Eclipse Proton v.8.9. The prescription used for each plan was 63 Gy in 28 fractions. The contours for spinal cord, right carotid artery, left carotid artery, and normal tissue were created with respect to the patient's bony anatomy so that proper comparisons of doses could be made with respect to volume. An example of the different isodose distributions will be shown. The data collection for comparison purposes includes: clinical treatment volume coverage, dose to spinal cord, dose to carotid arteries, and dose to normal tissue. Data comparisons will be displayed graphically showing the maximum, mean, median, and ranges of doses.

Authors:
; ;  [1];  [1]; ;  [1]
  1. University of Texas M.D. Anderson Cancer Center, School of Health Professions, Houston, TX (United States)
Publication Date:
OSTI Identifier:
22130408
Resource Type:
Journal Article
Journal Name:
Medical Dosimetry
Additional Journal Information:
Journal Volume: 37; Journal Issue: 2; Other Information: Copyright (c) 2012 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0958-3947
Country of Publication:
United States
Language:
English
Subject:
61 RADIATION PROTECTION AND DOSIMETRY; ALGORITHMS; BEAMS; CAROTID ARTERIES; COMPARATIVE EVALUATIONS; COMPUTERIZED TOMOGRAPHY; DOSIMETRY; NEOPLASMS; OPTIMIZATION; PATIENTS; PHOTONS; PLANNING; PROTONS; RADIATION DOSES; RADIOTHERAPY; SPINAL CORD

Citation Formats

Camingue, Pamela, Christian, Rochelle, Ng, Davin, Williams, Preston, E-mail: preston713@yahoo.com, Amin, Mayankkumar, and Roniger, Dominique L. Comparison of external beam treatment techniques for T1-2, N0, M0 glottic cancers. United States: N. p., 2012. Web. doi:10.1016/J.MEDDOS.2011.08.002.
Camingue, Pamela, Christian, Rochelle, Ng, Davin, Williams, Preston, E-mail: preston713@yahoo.com, Amin, Mayankkumar, & Roniger, Dominique L. Comparison of external beam treatment techniques for T1-2, N0, M0 glottic cancers. United States. doi:10.1016/J.MEDDOS.2011.08.002.
Camingue, Pamela, Christian, Rochelle, Ng, Davin, Williams, Preston, E-mail: preston713@yahoo.com, Amin, Mayankkumar, and Roniger, Dominique L. Sun . "Comparison of external beam treatment techniques for T1-2, N0, M0 glottic cancers". United States. doi:10.1016/J.MEDDOS.2011.08.002.
@article{osti_22130408,
title = {Comparison of external beam treatment techniques for T1-2, N0, M0 glottic cancers},
author = {Camingue, Pamela and Christian, Rochelle and Ng, Davin and Williams, Preston, E-mail: preston713@yahoo.com and Amin, Mayankkumar and Roniger, Dominique L.},
abstractNote = {The purpose of this study was to compare 4 different external beam radiation therapy treatment techniques for the treatment of T1-2, N0, M0 glottic cancers: traditional lateral beams with wedges (3D), 5-field intensity-modulated radiation therapy (IMRT), volumetric modulated arc therapy (VMAT), and proton therapy. Treatment plans in each technique were created for 10 patients using consistent planning parameters. The photon treatment plans were optimized using Philips Pinnacle{sub 3} v.9 and the IMRT and VMAT plans used the Direct Machine Parameter Optimization algorithm. The proton treatment plans were optimized using Varian Eclipse Proton v.8.9. The prescription used for each plan was 63 Gy in 28 fractions. The contours for spinal cord, right carotid artery, left carotid artery, and normal tissue were created with respect to the patient's bony anatomy so that proper comparisons of doses could be made with respect to volume. An example of the different isodose distributions will be shown. The data collection for comparison purposes includes: clinical treatment volume coverage, dose to spinal cord, dose to carotid arteries, and dose to normal tissue. Data comparisons will be displayed graphically showing the maximum, mean, median, and ranges of doses.},
doi = {10.1016/J.MEDDOS.2011.08.002},
journal = {Medical Dosimetry},
issn = {0958-3947},
number = 2,
volume = 37,
place = {United States},
year = {2012},
month = {7}
}