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Title: A case report on bilateral partial breast irradiation using SAVI

Abstract

To assess dosimetric parameters in a case study where bilateral accelerated partial breast irradiation (APBI) is delivered using a strut-adjusted volume implant (SAVI) device. A 59-year-old female received APBI in both breasts over 5 days, with fractions of 3.4 Gy twice daily. A Vac-lok system was used for immobilization, and a C-arm was used for daily imaging. We generated dose-volume histograms (DVHs) for the brachytherapy plans to derive several important biologic factors. We calculated the normal tissue complication probability (NTCP), equivalent uniform dose (EUD), and tumor control probability (TCP) using the Lyman-Kutcher-Burman model parameters {alpha} = 0.3 Gy{sup -1}, {alpha}/{beta} = 4 Gy, n = 0.1, and m = 0.3. In addition, we assessed the dose homogeneity index (DHI), overdose index, and dose nonuniformity ratio. D95 was >95% and V150 was <50 mL for both breasts. The DHIs were 0.469 and 0.512 for the left and right breasts, respectively. The EUDs (normalized to 3.4 Gy b.i.d.) were 33.53 and 29.10 Gy. The TCPs were estimated at 99.2% and 99.9%, whereas the NTCP values were 4.2% and 2.57%. In this clinical case, we were able to quantify the dosimetric parameters of an APBI treatment performed with a SAVI device.

Authors:
 [1];  [2]; ; ;  [1]
  1. Radiation Oncology, St. Vincent Hospital, Green Bay, WI (United States)
  2. Southeast Alabama Medical Center, Radiation Oncology Department, Dothan, AL 36301 (United States)
Publication Date:
OSTI Identifier:
22130407
Resource Type:
Journal Article
Journal Name:
Medical Dosimetry
Additional Journal Information:
Journal Volume: 37; Journal Issue: 2; Other Information: Copyright (c) 2012 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0958-3947
Country of Publication:
United States
Language:
English
Subject:
61 RADIATION PROTECTION AND DOSIMETRY; BRACHYTHERAPY; DOSIMETRY; EQUIPMENT; FEMALES; IMPLANTS; IRRADIATION; MAMMARY GLANDS; NEOPLASMS; PROBABILITY; RADIATION DOSES

Citation Formats

Gloi, Aime M., E-mail: agloi@stvgb.org, Buchanan, Robert, Nuskind, Jeff, Zuge, Corrie, and Goettler, Anndrea. A case report on bilateral partial breast irradiation using SAVI. United States: N. p., 2012. Web. doi:10.1016/J.MEDDOS.2011.08.001.
Gloi, Aime M., E-mail: agloi@stvgb.org, Buchanan, Robert, Nuskind, Jeff, Zuge, Corrie, & Goettler, Anndrea. A case report on bilateral partial breast irradiation using SAVI. United States. doi:10.1016/J.MEDDOS.2011.08.001.
Gloi, Aime M., E-mail: agloi@stvgb.org, Buchanan, Robert, Nuskind, Jeff, Zuge, Corrie, and Goettler, Anndrea. Sun . "A case report on bilateral partial breast irradiation using SAVI". United States. doi:10.1016/J.MEDDOS.2011.08.001.
@article{osti_22130407,
title = {A case report on bilateral partial breast irradiation using SAVI},
author = {Gloi, Aime M., E-mail: agloi@stvgb.org and Buchanan, Robert and Nuskind, Jeff and Zuge, Corrie and Goettler, Anndrea},
abstractNote = {To assess dosimetric parameters in a case study where bilateral accelerated partial breast irradiation (APBI) is delivered using a strut-adjusted volume implant (SAVI) device. A 59-year-old female received APBI in both breasts over 5 days, with fractions of 3.4 Gy twice daily. A Vac-lok system was used for immobilization, and a C-arm was used for daily imaging. We generated dose-volume histograms (DVHs) for the brachytherapy plans to derive several important biologic factors. We calculated the normal tissue complication probability (NTCP), equivalent uniform dose (EUD), and tumor control probability (TCP) using the Lyman-Kutcher-Burman model parameters {alpha} = 0.3 Gy{sup -1}, {alpha}/{beta} = 4 Gy, n = 0.1, and m = 0.3. In addition, we assessed the dose homogeneity index (DHI), overdose index, and dose nonuniformity ratio. D95 was >95% and V150 was <50 mL for both breasts. The DHIs were 0.469 and 0.512 for the left and right breasts, respectively. The EUDs (normalized to 3.4 Gy b.i.d.) were 33.53 and 29.10 Gy. The TCPs were estimated at 99.2% and 99.9%, whereas the NTCP values were 4.2% and 2.57%. In this clinical case, we were able to quantify the dosimetric parameters of an APBI treatment performed with a SAVI device.},
doi = {10.1016/J.MEDDOS.2011.08.001},
journal = {Medical Dosimetry},
issn = {0958-3947},
number = 2,
volume = 37,
place = {United States},
year = {2012},
month = {7}
}