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Title: Low energy electron stimulated desorption from DNA films dosed with oxygen

Abstract

Desorption of anions stimulated by 1-18 eV electron impact on self-assembled monolayer (SAM) films of single DNA strands is measured as a function of film temperature (50-250 K). The SAMs, composed of 10 nucleotides, are dosed with O{sub 2}. The OH{sup -} desorption yields increase markedly with exposure to O{sub 2} at 50 K and are further enhanced upon heating. In contrast, the desorption yields of O{sup -}, attributable to dissociative electron attachment to trapped O{sub 2} molecules decrease with heating. Irradiation of the DNA films prior to the deposition of O{sub 2} shows that this surprising increase in OH{sup -} desorption, at elevated temperatures, arises from the reaction of O{sub 2} with damaged DNA sites. These results thus appear to be a manifestation of the so-called 'oxygen fixation' effect, well known in radiobiology.

Authors:
; ; ; ;  [1]
  1. Groupe en sciences des radiations, Faculte de medecine et des sciences de la sante, Universite de Sherbrooke, Sherbrooke, Quebec J1H 5N4 (Canada)
Publication Date:
OSTI Identifier:
22100643
Resource Type:
Journal Article
Journal Name:
Journal of Chemical Physics
Additional Journal Information:
Journal Volume: 136; Journal Issue: 23; Other Information: (c) 2012 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0021-9606
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE; 75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY; 37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; 63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; ANIONS; DEPOSITION; DESORPTION; DNA; ELECTRON ATTACHMENT; ELECTRONS; EV RANGE 01-10; EV RANGE 10-100; FILMS; HEATING; ION-MOLECULE COLLISIONS; IRRADIATION; NUCLEOTIDES; OXYGEN; RADIOBIOLOGY; TEMPERATURE RANGE 0013-0065 K; TEMPERATURE RANGE 0065-0273 K

Citation Formats

Mirsaleh-Kohan, Nasrin, Bass, Andrew D., Cloutier, Pierre, Massey, Sylvain, and Sanche, Leon. Low energy electron stimulated desorption from DNA films dosed with oxygen. United States: N. p., 2012. Web. doi:10.1063/1.4729781.
Mirsaleh-Kohan, Nasrin, Bass, Andrew D., Cloutier, Pierre, Massey, Sylvain, & Sanche, Leon. Low energy electron stimulated desorption from DNA films dosed with oxygen. United States. doi:10.1063/1.4729781.
Mirsaleh-Kohan, Nasrin, Bass, Andrew D., Cloutier, Pierre, Massey, Sylvain, and Sanche, Leon. Thu . "Low energy electron stimulated desorption from DNA films dosed with oxygen". United States. doi:10.1063/1.4729781.
@article{osti_22100643,
title = {Low energy electron stimulated desorption from DNA films dosed with oxygen},
author = {Mirsaleh-Kohan, Nasrin and Bass, Andrew D. and Cloutier, Pierre and Massey, Sylvain and Sanche, Leon},
abstractNote = {Desorption of anions stimulated by 1-18 eV electron impact on self-assembled monolayer (SAM) films of single DNA strands is measured as a function of film temperature (50-250 K). The SAMs, composed of 10 nucleotides, are dosed with O{sub 2}. The OH{sup -} desorption yields increase markedly with exposure to O{sub 2} at 50 K and are further enhanced upon heating. In contrast, the desorption yields of O{sup -}, attributable to dissociative electron attachment to trapped O{sub 2} molecules decrease with heating. Irradiation of the DNA films prior to the deposition of O{sub 2} shows that this surprising increase in OH{sup -} desorption, at elevated temperatures, arises from the reaction of O{sub 2} with damaged DNA sites. These results thus appear to be a manifestation of the so-called 'oxygen fixation' effect, well known in radiobiology.},
doi = {10.1063/1.4729781},
journal = {Journal of Chemical Physics},
issn = {0021-9606},
number = 23,
volume = 136,
place = {United States},
year = {2012},
month = {6}
}