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Title: Metal artifact reduction strategies for improved attenuation correction in hybrid PET/CT imaging

Abstract

Metallic implants are known to generate bright and dark streaking artifacts in x-ray computed tomography (CT) images, which in turn propagate to corresponding functional positron emission tomography (PET) images during the CT-based attenuation correction procedure commonly used on hybrid clinical PET/CT scanners. Therefore, visual artifacts and overestimation and/or underestimation of the tracer uptake in regions adjacent to metallic implants are likely to occur and as such, inaccurate quantification of the tracer uptake and potential erroneous clinical interpretation of PET images is expected. Accurate quantification of PET data requires metal artifact reduction (MAR) of the CT images prior to the application of the CT-based attenuation correction procedure. In this review, the origins of metallic artifacts and their impact on clinical PET/CT imaging are discussed. Moreover, a brief overview of proposed MAR methods and their advantages and drawbacks is presented. Although most of the presented MAR methods are mainly developed for diagnostic CT imaging, their potential application in PET/CT imaging is highlighted. The challenges associated with comparative evaluation of these methods in a clinical environment in the absence of a gold standard are also discussed.

Authors:
; ;  [1];  [2];  [3]
  1. Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, 9700 RB Groningen (Netherlands)
  2. (Switzerland)
  3. (Switzerland) and Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, 9700 RB Groningen (Netherlands)
Publication Date:
OSTI Identifier:
22100639
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 39; Journal Issue: 6; Other Information: (c) 2012 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
07 ISOTOPES AND RADIATION SOURCES; ATTENUATION; CAT SCANNING; GOLD; IMAGES; POSITRON COMPUTED TOMOGRAPHY; RADIATION SOURCE IMPLANTS; STANDARDS; X RADIATION

Citation Formats

Abdoli, Mehrsima, Dierckx, Rudi A. J. O., Zaidi, Habib, Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211 Geneva, and Geneva Neuroscience Center, Geneva University, CH-1205 Geneva. Metal artifact reduction strategies for improved attenuation correction in hybrid PET/CT imaging. United States: N. p., 2012. Web. doi:10.1118/1.4709599.
Abdoli, Mehrsima, Dierckx, Rudi A. J. O., Zaidi, Habib, Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211 Geneva, & Geneva Neuroscience Center, Geneva University, CH-1205 Geneva. Metal artifact reduction strategies for improved attenuation correction in hybrid PET/CT imaging. United States. doi:10.1118/1.4709599.
Abdoli, Mehrsima, Dierckx, Rudi A. J. O., Zaidi, Habib, Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211 Geneva, and Geneva Neuroscience Center, Geneva University, CH-1205 Geneva. Fri . "Metal artifact reduction strategies for improved attenuation correction in hybrid PET/CT imaging". United States. doi:10.1118/1.4709599.
@article{osti_22100639,
title = {Metal artifact reduction strategies for improved attenuation correction in hybrid PET/CT imaging},
author = {Abdoli, Mehrsima and Dierckx, Rudi A. J. O. and Zaidi, Habib and Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211 Geneva and Geneva Neuroscience Center, Geneva University, CH-1205 Geneva},
abstractNote = {Metallic implants are known to generate bright and dark streaking artifacts in x-ray computed tomography (CT) images, which in turn propagate to corresponding functional positron emission tomography (PET) images during the CT-based attenuation correction procedure commonly used on hybrid clinical PET/CT scanners. Therefore, visual artifacts and overestimation and/or underestimation of the tracer uptake in regions adjacent to metallic implants are likely to occur and as such, inaccurate quantification of the tracer uptake and potential erroneous clinical interpretation of PET images is expected. Accurate quantification of PET data requires metal artifact reduction (MAR) of the CT images prior to the application of the CT-based attenuation correction procedure. In this review, the origins of metallic artifacts and their impact on clinical PET/CT imaging are discussed. Moreover, a brief overview of proposed MAR methods and their advantages and drawbacks is presented. Although most of the presented MAR methods are mainly developed for diagnostic CT imaging, their potential application in PET/CT imaging is highlighted. The challenges associated with comparative evaluation of these methods in a clinical environment in the absence of a gold standard are also discussed.},
doi = {10.1118/1.4709599},
journal = {Medical Physics},
number = 6,
volume = 39,
place = {United States},
year = {Fri Jun 15 00:00:00 EDT 2012},
month = {Fri Jun 15 00:00:00 EDT 2012}
}