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Title: Noise in x-ray grating-based phase-contrast imaging

Abstract

Purpose: Grating-based x-ray phase-contrast imaging is a fast developing new modality not only for medical imaging, but as well for other fields such as material sciences. While these many possible applications arise, the knowledge of the noise behavior is essential. Methods: In this work, the authors used a least squares fitting algorithm to calculate the noise behavior of the three quantities absorption, differential phase, and dark-field image. Further, the calculated error formula of the differential phase image was verified by measurements. Therefore, a Talbot interferometer was setup, using a microfocus x-ray tube as source and a Timepix detector for photon counting. Additionally, simulations regarding this topic were performed. Results: It turned out that the variance of the reconstructed phase is only dependent of the total number of photons used to generate the phase image and the visibility of the experimental setup. These results could be evaluated in measurements as well as in simulations. Furthermore, the correlation between absorption and dark-field image was calculated. Conclusions: These results provide the understanding of the noise characteristics of grating-based phase-contrast imaging and will help to improve image quality.

Authors:
; ; ; ; ; ; ;  [1];  [2];  [2]
  1. ECAP--Erlangen Centre for Astroparticle Physics, University of Erlangen-Nuremberg, Erwin-Rommel-Str. 1, 91058 Erlangen (Germany)
  2. (Germany)
Publication Date:
OSTI Identifier:
22098562
Resource Type:
Journal Article
Journal Name:
Medical Physics
Additional Journal Information:
Journal Volume: 38; Journal Issue: 7; Other Information: (c) 2011 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-2405
Country of Publication:
United States
Language:
English
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; 62 RADIOLOGY AND NUCLEAR MEDICINE; ABSORPTION; APPROXIMATIONS; CORRELATIONS; DIFFRACTION GRATINGS; ERRORS; GRATINGS; IMAGES; INTERFEROMETERS; LEAST SQUARE FIT; NOISE; PHOTONS; X RADIATION; X-RAY TUBES

Citation Formats

Weber, Thomas, Bartl, Peter, Bayer, Florian, Durst, Juergen, Haas, Wilhelm, Michel, Thilo, Ritter, Andre, Anton, Gisela, Pattern Recognition Lab, University of Erlangen-Nuremberg, Martensstr. 3, 91058 Erlangen, Germany and ECAP--Erlangen Centre for Astroparticle Physics, University of Erlangen-Nuremberg, Erwin-Rommel-Str. 1, 91058 Erlangen, and ECAP--Erlangen Centre for Astroparticle Physics, University of Erlangen-Nuremberg, Erwin-Rommel-Str. 1, 91058 Erlangen. Noise in x-ray grating-based phase-contrast imaging. United States: N. p., 2011. Web. doi:10.1118/1.3592935.
Weber, Thomas, Bartl, Peter, Bayer, Florian, Durst, Juergen, Haas, Wilhelm, Michel, Thilo, Ritter, Andre, Anton, Gisela, Pattern Recognition Lab, University of Erlangen-Nuremberg, Martensstr. 3, 91058 Erlangen, Germany and ECAP--Erlangen Centre for Astroparticle Physics, University of Erlangen-Nuremberg, Erwin-Rommel-Str. 1, 91058 Erlangen, & ECAP--Erlangen Centre for Astroparticle Physics, University of Erlangen-Nuremberg, Erwin-Rommel-Str. 1, 91058 Erlangen. Noise in x-ray grating-based phase-contrast imaging. United States. doi:10.1118/1.3592935.
Weber, Thomas, Bartl, Peter, Bayer, Florian, Durst, Juergen, Haas, Wilhelm, Michel, Thilo, Ritter, Andre, Anton, Gisela, Pattern Recognition Lab, University of Erlangen-Nuremberg, Martensstr. 3, 91058 Erlangen, Germany and ECAP--Erlangen Centre for Astroparticle Physics, University of Erlangen-Nuremberg, Erwin-Rommel-Str. 1, 91058 Erlangen, and ECAP--Erlangen Centre for Astroparticle Physics, University of Erlangen-Nuremberg, Erwin-Rommel-Str. 1, 91058 Erlangen. Fri . "Noise in x-ray grating-based phase-contrast imaging". United States. doi:10.1118/1.3592935.
@article{osti_22098562,
title = {Noise in x-ray grating-based phase-contrast imaging},
author = {Weber, Thomas and Bartl, Peter and Bayer, Florian and Durst, Juergen and Haas, Wilhelm and Michel, Thilo and Ritter, Andre and Anton, Gisela and Pattern Recognition Lab, University of Erlangen-Nuremberg, Martensstr. 3, 91058 Erlangen, Germany and ECAP--Erlangen Centre for Astroparticle Physics, University of Erlangen-Nuremberg, Erwin-Rommel-Str. 1, 91058 Erlangen and ECAP--Erlangen Centre for Astroparticle Physics, University of Erlangen-Nuremberg, Erwin-Rommel-Str. 1, 91058 Erlangen},
abstractNote = {Purpose: Grating-based x-ray phase-contrast imaging is a fast developing new modality not only for medical imaging, but as well for other fields such as material sciences. While these many possible applications arise, the knowledge of the noise behavior is essential. Methods: In this work, the authors used a least squares fitting algorithm to calculate the noise behavior of the three quantities absorption, differential phase, and dark-field image. Further, the calculated error formula of the differential phase image was verified by measurements. Therefore, a Talbot interferometer was setup, using a microfocus x-ray tube as source and a Timepix detector for photon counting. Additionally, simulations regarding this topic were performed. Results: It turned out that the variance of the reconstructed phase is only dependent of the total number of photons used to generate the phase image and the visibility of the experimental setup. These results could be evaluated in measurements as well as in simulations. Furthermore, the correlation between absorption and dark-field image was calculated. Conclusions: These results provide the understanding of the noise characteristics of grating-based phase-contrast imaging and will help to improve image quality.},
doi = {10.1118/1.3592935},
journal = {Medical Physics},
issn = {0094-2405},
number = 7,
volume = 38,
place = {United States},
year = {2011},
month = {7}
}