skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Validation of GPUMCD for low-energy brachytherapy seed dosimetry

Abstract

Purpose: To validate GPUMCD, a new package for fast Monte Carlo dose calculations based on the GPU (graphics processing unit), as a tool for low-energy single seed brachytherapy dosimetry for specific seed models. As the currently accepted method of dose calculation in low-energy brachytherapy computations relies on severe approximations, a Monte Carlo based approach would result in more accurate dose calculations, taking in to consideration the patient anatomy as well as interseed attenuation. The first step is to evaluate the capability of GPUMCD to reproduce low-energy, single source, brachytherapy calculations which could ultimately result in fast and accurate, Monte Carlo based, brachytherapy dose calculations for routine planning. Methods: A mixed geometry engine was integrated to GPUMCD capable of handling parametric as well as voxelized geometries. In order to evaluate GPUMCD for brachytherapy calculations, several dosimetry parameters were computed and compared to values found in the literature. These parameters, defined by the AAPM Task-Group No. 43, are the radial dose function, the 2D anisotropy function, and the dose rate constant. These three parameters were computed for two different brachytherapy sources: the Amersham OncoSeed 6711 and the Imagyn IsoStar IS-12501. Results: GPUMCD was shown to yield dosimetric parameters similar to those foundmore » in the literature. It reproduces radial dose functions to within 1.25% for both sources in the 0.5< r <10 cm range. The 2D anisotropy function was found to be within 3% at r = 5 cm and within 4% at r = 1 cm. The dose rate constants obtained were within the range of other values reported in the literature.Conclusion: GPUMCD was shown to be able to reproduce various TG-43 parameters for two different low-energy brachytherapy sources found in the literature. The next step is to test GPUMCD as a fast clinical Monte Carlo brachytherapy dose calculations with multiple seeds and patient geometry, potentially providing more accurate results than the TG-43 formalism while being much faster than calculations using general purpose Monte Carlo codes.« less

Authors:
; ; ;  [1];  [2];  [3]
  1. Ecole polytechnique de Montreal, Departement de genie informatique et genie logiciel, 2500 chemin de Polytechnique, Montreal, QC, H3T 1J4 (Canada)
  2. (CHUQ), 11 Cote du Palais, Quebec, QC, G1R 2J6 (Canada)
  3. (Canada) and Departement de radio-oncologie and Centre de recherche du CHUM, Centre hospitalier de l'Universite de Montreal (CHUM), Montreal, QC, H2L 4M1 (Canada)
Publication Date:
OSTI Identifier:
22098558
Resource Type:
Journal Article
Journal Name:
Medical Physics
Additional Journal Information:
Journal Volume: 38; Journal Issue: 7; Other Information: (c) 2011 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-2405
Country of Publication:
United States
Language:
English
Subject:
61 RADIATION PROTECTION AND DOSIMETRY; 62 RADIOLOGY AND NUCLEAR MEDICINE; ANISOTROPY; APPROXIMATIONS; BRACHYTHERAPY; COMPUTER GRAPHICS; DOSE RATES; DOSIMETRY; MONTE CARLO METHOD; PATIENTS; PLANNING; PROCESSING; RADIATION DOSES; RADIATION PROTECTION

Citation Formats

Hissoiny, Sami, Ozell, Benoit, Despres, Philippe, Carrier, Jean-Francois, Departement de radio-oncologie, Centre hospitalier universitaire de Quebec, and Departement de physique, Universite de Montreal, Montreal, QC. Validation of GPUMCD for low-energy brachytherapy seed dosimetry. United States: N. p., 2011. Web. doi:10.1118/1.3598441.
Hissoiny, Sami, Ozell, Benoit, Despres, Philippe, Carrier, Jean-Francois, Departement de radio-oncologie, Centre hospitalier universitaire de Quebec, & Departement de physique, Universite de Montreal, Montreal, QC. Validation of GPUMCD for low-energy brachytherapy seed dosimetry. United States. doi:10.1118/1.3598441.
Hissoiny, Sami, Ozell, Benoit, Despres, Philippe, Carrier, Jean-Francois, Departement de radio-oncologie, Centre hospitalier universitaire de Quebec, and Departement de physique, Universite de Montreal, Montreal, QC. Fri . "Validation of GPUMCD for low-energy brachytherapy seed dosimetry". United States. doi:10.1118/1.3598441.
@article{osti_22098558,
title = {Validation of GPUMCD for low-energy brachytherapy seed dosimetry},
author = {Hissoiny, Sami and Ozell, Benoit and Despres, Philippe and Carrier, Jean-Francois and Departement de radio-oncologie, Centre hospitalier universitaire de Quebec and Departement de physique, Universite de Montreal, Montreal, QC},
abstractNote = {Purpose: To validate GPUMCD, a new package for fast Monte Carlo dose calculations based on the GPU (graphics processing unit), as a tool for low-energy single seed brachytherapy dosimetry for specific seed models. As the currently accepted method of dose calculation in low-energy brachytherapy computations relies on severe approximations, a Monte Carlo based approach would result in more accurate dose calculations, taking in to consideration the patient anatomy as well as interseed attenuation. The first step is to evaluate the capability of GPUMCD to reproduce low-energy, single source, brachytherapy calculations which could ultimately result in fast and accurate, Monte Carlo based, brachytherapy dose calculations for routine planning. Methods: A mixed geometry engine was integrated to GPUMCD capable of handling parametric as well as voxelized geometries. In order to evaluate GPUMCD for brachytherapy calculations, several dosimetry parameters were computed and compared to values found in the literature. These parameters, defined by the AAPM Task-Group No. 43, are the radial dose function, the 2D anisotropy function, and the dose rate constant. These three parameters were computed for two different brachytherapy sources: the Amersham OncoSeed 6711 and the Imagyn IsoStar IS-12501. Results: GPUMCD was shown to yield dosimetric parameters similar to those found in the literature. It reproduces radial dose functions to within 1.25% for both sources in the 0.5< r <10 cm range. The 2D anisotropy function was found to be within 3% at r = 5 cm and within 4% at r = 1 cm. The dose rate constants obtained were within the range of other values reported in the literature.Conclusion: GPUMCD was shown to be able to reproduce various TG-43 parameters for two different low-energy brachytherapy sources found in the literature. The next step is to test GPUMCD as a fast clinical Monte Carlo brachytherapy dose calculations with multiple seeds and patient geometry, potentially providing more accurate results than the TG-43 formalism while being much faster than calculations using general purpose Monte Carlo codes.},
doi = {10.1118/1.3598441},
journal = {Medical Physics},
issn = {0094-2405},
number = 7,
volume = 38,
place = {United States},
year = {2011},
month = {7}
}