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Title: Validation for 2D/3D registration I: A new gold standard data set

Abstract

Purpose: In this article, the authors propose a new gold standard data set for the validation of two-dimensional/three-dimensional (2D/3D) and 3D/3D image registration algorithms. Methods: A gold standard data set was produced using a fresh cadaver pig head with attached fiducial markers. The authors used several imaging modalities common in diagnostic imaging or radiotherapy, which include 64-slice computed tomography (CT), magnetic resonance imaging using Tl, T2, and proton density sequences, and cone beam CT imaging data. Radiographic data were acquired using kilovoltage and megavoltage imaging techniques. The image information reflects both anatomy and reliable fiducial marker information and improves over existing data sets by the level of anatomical detail, image data quality, and soft-tissue content. The markers on the 3D and 2D image data were segmented using ANALYZE 10.0 (AnalyzeDirect, Inc., Kansas City, KN) and an in-house software. Results: The projection distance errors and the expected target registration errors over all the image data sets were found to be less than 2.71 and 1.88 mm, respectively. Conclusions: The gold standard data set, obtained with state-of-the-art imaging technology, has the potential to improve the validation of 2D/3D and 3D/3D registration algorithms for image guided therapy.

Authors:
; ; ; ; ; ; ; ; ; ; ; ;  [1];  [2];  [3];  [3];  [3];  [3];  [3]
  1. Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090 (Austria)
  2. (Slovenia)
  3. (Austria)
Publication Date:
OSTI Identifier:
22096936
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 38; Journal Issue: 3; Other Information: (c) 2011 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ALGORITHMS; COMPUTER CODES; COMPUTERIZED TOMOGRAPHY; HEAD; IMAGE PROCESSING; IMAGES; INFORMATION; NMR IMAGING; PROTON DENSITY; RADIOTHERAPY; STANDARDS; SWINE; VALIDATION

Citation Formats

Pawiro, S. A., Markelj, P., Pernus, F., Gendrin, C., Figl, M., Weber, C., Kainberger, F., Noebauer-Huhmann, I., Bergmeister, H., Stock, M., Georg, D., Bergmann, H., Birkfellner, W., Laboratory of Imaging Technologies, Faculty of Electrical Engineering, University of Ljubljana, Trzaska Cesta 25, Ljubljana SI-1000, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090, University Clinic of Radiology, Division of Osteoradiology, Medical University of Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090, Department of Biomedical Research, Medical University Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090, University Clinic of Radiotherapy, Division of Medical Radiation Physics, Medical University of Vienna, Waehringer Guertel 18-20, AKH, Vienna A-1090, and Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090. Validation for 2D/3D registration I: A new gold standard data set. United States: N. p., 2011. Web. doi:10.1118/1.3553402.
Pawiro, S. A., Markelj, P., Pernus, F., Gendrin, C., Figl, M., Weber, C., Kainberger, F., Noebauer-Huhmann, I., Bergmeister, H., Stock, M., Georg, D., Bergmann, H., Birkfellner, W., Laboratory of Imaging Technologies, Faculty of Electrical Engineering, University of Ljubljana, Trzaska Cesta 25, Ljubljana SI-1000, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090, University Clinic of Radiology, Division of Osteoradiology, Medical University of Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090, Department of Biomedical Research, Medical University Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090, University Clinic of Radiotherapy, Division of Medical Radiation Physics, Medical University of Vienna, Waehringer Guertel 18-20, AKH, Vienna A-1090, & Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090. Validation for 2D/3D registration I: A new gold standard data set. United States. doi:10.1118/1.3553402.
Pawiro, S. A., Markelj, P., Pernus, F., Gendrin, C., Figl, M., Weber, C., Kainberger, F., Noebauer-Huhmann, I., Bergmeister, H., Stock, M., Georg, D., Bergmann, H., Birkfellner, W., Laboratory of Imaging Technologies, Faculty of Electrical Engineering, University of Ljubljana, Trzaska Cesta 25, Ljubljana SI-1000, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090, University Clinic of Radiology, Division of Osteoradiology, Medical University of Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090, Department of Biomedical Research, Medical University Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090, University Clinic of Radiotherapy, Division of Medical Radiation Physics, Medical University of Vienna, Waehringer Guertel 18-20, AKH, Vienna A-1090, and Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090. Tue . "Validation for 2D/3D registration I: A new gold standard data set". United States. doi:10.1118/1.3553402.
@article{osti_22096936,
title = {Validation for 2D/3D registration I: A new gold standard data set},
author = {Pawiro, S. A. and Markelj, P. and Pernus, F. and Gendrin, C. and Figl, M. and Weber, C. and Kainberger, F. and Noebauer-Huhmann, I. and Bergmeister, H. and Stock, M. and Georg, D. and Bergmann, H. and Birkfellner, W. and Laboratory of Imaging Technologies, Faculty of Electrical Engineering, University of Ljubljana, Trzaska Cesta 25, Ljubljana SI-1000 and Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090 and University Clinic of Radiology, Division of Osteoradiology, Medical University of Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090 and Department of Biomedical Research, Medical University Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090 and University Clinic of Radiotherapy, Division of Medical Radiation Physics, Medical University of Vienna, Waehringer Guertel 18-20, AKH, Vienna A-1090 and Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, AKH-4L, Waehringer Guertel 18-20, Vienna A-1090},
abstractNote = {Purpose: In this article, the authors propose a new gold standard data set for the validation of two-dimensional/three-dimensional (2D/3D) and 3D/3D image registration algorithms. Methods: A gold standard data set was produced using a fresh cadaver pig head with attached fiducial markers. The authors used several imaging modalities common in diagnostic imaging or radiotherapy, which include 64-slice computed tomography (CT), magnetic resonance imaging using Tl, T2, and proton density sequences, and cone beam CT imaging data. Radiographic data were acquired using kilovoltage and megavoltage imaging techniques. The image information reflects both anatomy and reliable fiducial marker information and improves over existing data sets by the level of anatomical detail, image data quality, and soft-tissue content. The markers on the 3D and 2D image data were segmented using ANALYZE 10.0 (AnalyzeDirect, Inc., Kansas City, KN) and an in-house software. Results: The projection distance errors and the expected target registration errors over all the image data sets were found to be less than 2.71 and 1.88 mm, respectively. Conclusions: The gold standard data set, obtained with state-of-the-art imaging technology, has the potential to improve the validation of 2D/3D and 3D/3D registration algorithms for image guided therapy.},
doi = {10.1118/1.3553402},
journal = {Medical Physics},
number = 3,
volume = 38,
place = {United States},
year = {Tue Mar 15 00:00:00 EDT 2011},
month = {Tue Mar 15 00:00:00 EDT 2011}
}