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Title: Technical Note: DIRART- A software suite for deformable image registration and adaptive radiotherapy research

Abstract

Purpose: Recent years have witnessed tremendous progress in image guide radiotherapy technology and a growing interest in the possibilities for adapting treatment planning and delivery over the course of treatment. One obstacle faced by the research community has been the lack of a comprehensive open-source software toolkit dedicated for adaptive radiotherapy (ART). To address this need, the authors have developed a software suite called the Deformable Image Registration and Adaptive Radiotherapy Toolkit (DIRART). Methods: DIRART is an open-source toolkit developed in MATLAB. It is designed in an object-oriented style with focus on user-friendliness, features, and flexibility. It contains four classes of DIR algorithms, including the newer inverse consistency algorithms to provide consistent displacement vector field in both directions. It also contains common ART functions, an integrated graphical user interface, a variety of visualization and image-processing features, dose metric analysis functions, and interface routines. These interface routines make DIRART a powerful complement to the Computational Environment for Radiotherapy Research (CERR) and popular image-processing toolkits such as ITK. Results: DIRART provides a set of image processing/registration algorithms and postprocessing functions to facilitate the development and testing of DIR algorithms. It also offers a good amount of options for DIR results visualization, evaluation,more » and validation. Conclusions: By exchanging data with treatment planning systems via DICOM-RT files and CERR, and by bringing image registration algorithms closer to radiotherapy applications, DIRART is potentially a convenient and flexible platform that may facilitate ART and DIR research.« less

Authors:
; ; ; ; ; ; ; ;  [1]
  1. Department of Radiation Oncology, School of Medicine, Washington University in Saint Louis, Missouri 63110 (United States)
Publication Date:
OSTI Identifier:
22096886
Resource Type:
Journal Article
Journal Name:
Medical Physics
Additional Journal Information:
Journal Volume: 38; Journal Issue: 1; Other Information: (c) 2011 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-2405
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 60 APPLIED LIFE SCIENCES; ALGORITHMS; COMPUTER CODES; EVALUATION; IMAGE PROCESSING; IMAGES; METRICS; PLANNING; RADIOTHERAPY; VALIDATION

Citation Formats

Deshan, Yang, Brame, Scott, El Naqa, Issam, Aditya, Apte, Yu, Wu, Murty Goddu, S., Mutic, Sasa, Deasy, Joseph O., and Low, Daniel A. Technical Note: DIRART- A software suite for deformable image registration and adaptive radiotherapy research. United States: N. p., 2011. Web. doi:10.1118/1.3521468.
Deshan, Yang, Brame, Scott, El Naqa, Issam, Aditya, Apte, Yu, Wu, Murty Goddu, S., Mutic, Sasa, Deasy, Joseph O., & Low, Daniel A. Technical Note: DIRART- A software suite for deformable image registration and adaptive radiotherapy research. United States. https://doi.org/10.1118/1.3521468
Deshan, Yang, Brame, Scott, El Naqa, Issam, Aditya, Apte, Yu, Wu, Murty Goddu, S., Mutic, Sasa, Deasy, Joseph O., and Low, Daniel A. 2011. "Technical Note: DIRART- A software suite for deformable image registration and adaptive radiotherapy research". United States. https://doi.org/10.1118/1.3521468.
@article{osti_22096886,
title = {Technical Note: DIRART- A software suite for deformable image registration and adaptive radiotherapy research},
author = {Deshan, Yang and Brame, Scott and El Naqa, Issam and Aditya, Apte and Yu, Wu and Murty Goddu, S. and Mutic, Sasa and Deasy, Joseph O. and Low, Daniel A.},
abstractNote = {Purpose: Recent years have witnessed tremendous progress in image guide radiotherapy technology and a growing interest in the possibilities for adapting treatment planning and delivery over the course of treatment. One obstacle faced by the research community has been the lack of a comprehensive open-source software toolkit dedicated for adaptive radiotherapy (ART). To address this need, the authors have developed a software suite called the Deformable Image Registration and Adaptive Radiotherapy Toolkit (DIRART). Methods: DIRART is an open-source toolkit developed in MATLAB. It is designed in an object-oriented style with focus on user-friendliness, features, and flexibility. It contains four classes of DIR algorithms, including the newer inverse consistency algorithms to provide consistent displacement vector field in both directions. It also contains common ART functions, an integrated graphical user interface, a variety of visualization and image-processing features, dose metric analysis functions, and interface routines. These interface routines make DIRART a powerful complement to the Computational Environment for Radiotherapy Research (CERR) and popular image-processing toolkits such as ITK. Results: DIRART provides a set of image processing/registration algorithms and postprocessing functions to facilitate the development and testing of DIR algorithms. It also offers a good amount of options for DIR results visualization, evaluation, and validation. Conclusions: By exchanging data with treatment planning systems via DICOM-RT files and CERR, and by bringing image registration algorithms closer to radiotherapy applications, DIRART is potentially a convenient and flexible platform that may facilitate ART and DIR research.},
doi = {10.1118/1.3521468},
url = {https://www.osti.gov/biblio/22096886}, journal = {Medical Physics},
issn = {0094-2405},
number = 1,
volume = 38,
place = {United States},
year = {Sat Jan 15 00:00:00 EST 2011},
month = {Sat Jan 15 00:00:00 EST 2011}
}