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Title: Investigation of interaction of albumin molecules with diamond nanoparticles in aqueous solutions by dynamic light scattering

Abstract

The method of dynamic light scattering has been used to study the interaction of albumin molecules with diamond nanoparticles in aqueous solutions. It is shown that due to adsorption of albumin on diamond nanoparticles, larger size particles are formed. We have obtained the concentration dependences of the average hydrodynamic radius of these particles. It is found that the carboxylation of the surface of diamond nanoparticles and their pre-coating by albumin leads to a decrease in the adsorption of protein molecules on the surface of nanoparticles and to a decrease in their average hydrodynamic radius. We have also shown that in the range of concentrations of diamond nanoparticles 2-10 {mu}g mL{sup -1}, their interaction with albumin molecules at different pH has a different character.

Authors:
; ; ; ; ; ; ; ;
Publication Date:
OSTI Identifier:
22043939
Resource Type:
Journal Article
Journal Name:
Quantum Electronics (Woodbury, N.Y.)
Additional Journal Information:
Journal Volume: 42; Journal Issue: 6; Other Information: Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 1063-7818
Country of Publication:
United States
Language:
English
Subject:
74 ATOMIC AND MOLECULAR PHYSICS; 71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; ADSORPTION; ALBUMINS; AQUEOUS SOLUTIONS; CARBOXYLATION; DIAMONDS; INTERACTIONS; LIGHT SCATTERING; MOLECULES; SURFACES

Citation Formats

Samsonova, Yu S, Priezzhev, A V, Lugovtsov, Andrei E, Petrova, G P, Gibizova, V V, Ye, Y.-S., Su, T.-H., Perevedentseva, Elena V, and Cheng, Chia-Liang. Investigation of interaction of albumin molecules with diamond nanoparticles in aqueous solutions by dynamic light scattering. United States: N. p., 2012. Web. doi:10.1070/QE2012V042N06ABEH014903.
Samsonova, Yu S, Priezzhev, A V, Lugovtsov, Andrei E, Petrova, G P, Gibizova, V V, Ye, Y.-S., Su, T.-H., Perevedentseva, Elena V, & Cheng, Chia-Liang. Investigation of interaction of albumin molecules with diamond nanoparticles in aqueous solutions by dynamic light scattering. United States. doi:10.1070/QE2012V042N06ABEH014903.
Samsonova, Yu S, Priezzhev, A V, Lugovtsov, Andrei E, Petrova, G P, Gibizova, V V, Ye, Y.-S., Su, T.-H., Perevedentseva, Elena V, and Cheng, Chia-Liang. Sat . "Investigation of interaction of albumin molecules with diamond nanoparticles in aqueous solutions by dynamic light scattering". United States. doi:10.1070/QE2012V042N06ABEH014903.
@article{osti_22043939,
title = {Investigation of interaction of albumin molecules with diamond nanoparticles in aqueous solutions by dynamic light scattering},
author = {Samsonova, Yu S and Priezzhev, A V and Lugovtsov, Andrei E and Petrova, G P and Gibizova, V V and Ye, Y.-S. and Su, T.-H. and Perevedentseva, Elena V and Cheng, Chia-Liang},
abstractNote = {The method of dynamic light scattering has been used to study the interaction of albumin molecules with diamond nanoparticles in aqueous solutions. It is shown that due to adsorption of albumin on diamond nanoparticles, larger size particles are formed. We have obtained the concentration dependences of the average hydrodynamic radius of these particles. It is found that the carboxylation of the surface of diamond nanoparticles and their pre-coating by albumin leads to a decrease in the adsorption of protein molecules on the surface of nanoparticles and to a decrease in their average hydrodynamic radius. We have also shown that in the range of concentrations of diamond nanoparticles 2-10 {mu}g mL{sup -1}, their interaction with albumin molecules at different pH has a different character.},
doi = {10.1070/QE2012V042N06ABEH014903},
journal = {Quantum Electronics (Woodbury, N.Y.)},
issn = {1063-7818},
number = 6,
volume = 42,
place = {United States},
year = {2012},
month = {6}
}