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Title: Single-Institution Results of Image-Guided Nonplugged Percutaneous Versus Transjugular Liver Biopsy

Abstract

Purpose: To retrospectively review patients who underwent transjugular and image-guided percutaneous biopsy and compare the relative risk of ascites, thrombocytopenia, and coagulopathy. Materials and Methods: From August 2001 through February 2006, a total of 238 liver biopsies were performed. The radiologist reviewed all patient referrals for transjugular biopsy. These patients either underwent transjugular biopsy or were reassigned to percutaneous biopsy (crossover group). Patients referred to percutaneous image-guided liver biopsy underwent this same procedure. Biopsies were considered successful if a tissue diagnosis could be made from the samples obtained. Results: A total of 36 transjugular biopsies were performed with 3 total (8.3%) and 1 major (2.8%) complications. A total of 171 percutaneous biopsies were performed with 10 (5.8%) total and 3 (1.8%) major complications. The crossover group showed a total of 4 (12.9%) complications with 1 (3.2%) major complication. Sample adequacy was 91.9% for transjugular and 99.5% for percutaneous biopsy. Conclusion: Both transjugular and percutaneous liver biopsy techniques are efficacious and safe. Contraindications such as thrombocytopenia, coagulopathy, and ascites are indicators of greater complications but are not necessarily prevented by transjugular biopsy. Percutaneous biopsy more frequently yields a diagnostic specimen than transjugular biopsy.

Authors:
 [1]; ;  [2]
  1. University of Texas Health Science Center San Antonio (United States)
  2. Dartmouth-Hitchcock Medical Center, Division of Vascular and Interventional Radiology (United States)
Publication Date:
OSTI Identifier:
21608718
Resource Type:
Journal Article
Journal Name:
Cardiovascular and Interventional Radiology
Additional Journal Information:
Journal Volume: 34; Journal Issue: 2; Other Information: DOI: 10.1007/s00270-010-9924-9; Copyright (c) 2011 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0174-1551
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ASCITES; BIOPSY; DIAGNOSIS; HAZARDS; IMAGES; LIVER; MATERIALS; PATIENTS; BODY; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; GLANDS; ORGANS; PATHOLOGICAL CHANGES; SYMPTOMS

Citation Formats

Hardman, Rulon L., E-mail: hardmanr@uthscsa.edu, Perrich, Kiley D., and Silas, Anne M. Single-Institution Results of Image-Guided Nonplugged Percutaneous Versus Transjugular Liver Biopsy. United States: N. p., 2011. Web. doi:10.1007/S00270-010-9924-9.
Hardman, Rulon L., E-mail: hardmanr@uthscsa.edu, Perrich, Kiley D., & Silas, Anne M. Single-Institution Results of Image-Guided Nonplugged Percutaneous Versus Transjugular Liver Biopsy. United States. doi:10.1007/S00270-010-9924-9.
Hardman, Rulon L., E-mail: hardmanr@uthscsa.edu, Perrich, Kiley D., and Silas, Anne M. Fri . "Single-Institution Results of Image-Guided Nonplugged Percutaneous Versus Transjugular Liver Biopsy". United States. doi:10.1007/S00270-010-9924-9.
@article{osti_21608718,
title = {Single-Institution Results of Image-Guided Nonplugged Percutaneous Versus Transjugular Liver Biopsy},
author = {Hardman, Rulon L., E-mail: hardmanr@uthscsa.edu and Perrich, Kiley D. and Silas, Anne M.},
abstractNote = {Purpose: To retrospectively review patients who underwent transjugular and image-guided percutaneous biopsy and compare the relative risk of ascites, thrombocytopenia, and coagulopathy. Materials and Methods: From August 2001 through February 2006, a total of 238 liver biopsies were performed. The radiologist reviewed all patient referrals for transjugular biopsy. These patients either underwent transjugular biopsy or were reassigned to percutaneous biopsy (crossover group). Patients referred to percutaneous image-guided liver biopsy underwent this same procedure. Biopsies were considered successful if a tissue diagnosis could be made from the samples obtained. Results: A total of 36 transjugular biopsies were performed with 3 total (8.3%) and 1 major (2.8%) complications. A total of 171 percutaneous biopsies were performed with 10 (5.8%) total and 3 (1.8%) major complications. The crossover group showed a total of 4 (12.9%) complications with 1 (3.2%) major complication. Sample adequacy was 91.9% for transjugular and 99.5% for percutaneous biopsy. Conclusion: Both transjugular and percutaneous liver biopsy techniques are efficacious and safe. Contraindications such as thrombocytopenia, coagulopathy, and ascites are indicators of greater complications but are not necessarily prevented by transjugular biopsy. Percutaneous biopsy more frequently yields a diagnostic specimen than transjugular biopsy.},
doi = {10.1007/S00270-010-9924-9},
journal = {Cardiovascular and Interventional Radiology},
issn = {0174-1551},
number = 2,
volume = 34,
place = {United States},
year = {2011},
month = {4}
}