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Title: Ovarian Artery Embolization in Patients With Collateral Supply to Symptomatic Uterine Leiomyomata

Abstract

Purpose: To evaluate the safety and outcome of ovarian artery embolization (OAE) in patients with collateral supply to symptomatic uterine leiomyomata. Materials and Methods: Thirteen patients with relevant leiomyoma perfusion by way of enlarged ovarian arteries underwent additional OAE during the same (N = 10) or a second procedure (N = 3). Uterine artery embolization (UAE) was performed bilaterally in 10 and unilaterally in 2 patients with a single artery. One patient had no typical uterine arteries but bilaterally enlarged ovarian arteries, prompting bilateral OAE. OAE was accomplished with coil embolization in one and particle embolization in 12 patients. Symptoms before therapy and clinical outcome were assessed using a standardized questionnaire. Contrast-enhanced magnetic resonance (MR) imaging after embolization was available in 11 of 13 patients and was used to determine the percentage of fibroid infarction. Results: UAE and OAE were technically successful in all patients. One patient experienced prolonged irritation at the puncture site. Median clinical follow-up time was 16 months (range 4-37). Ten of 13 patients showed improvement or complete resolution of clinical symptoms. One patient reported only slight improvement of her symptoms. These women presented with regular menses. Two patients (15%), 47 and 48 years, both with unilateralmore » OAE, reported permanent amenorrhea directly after embolization. Their symptoms completely resolved. Seven patients showed complete and 4 showed >90% fibroid infarction after embolization therapy. Conclusions: OAE is technically safe and effective in patients with ovarian artery collateral supply to symptomatic uterine leiomyomata. The risk of permanent amenorrhea observed in this study is similar to the reported incidence after UAE.« less

Authors:
; ; ;
Publication Date:
OSTI Identifier:
21608639
Resource Type:
Journal Article
Journal Name:
Cardiovascular and Interventional Radiology
Additional Journal Information:
Journal Volume: 34; Journal Issue: 6; Other Information: DOI: 10.1007/s00270-010-9991-y; Copyright (c) 2011 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0174-1551
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ARTERIES; HAZARDS; MAGNETIC RESONANCE; MATERIALS; MENSTRUATION DISORDERS; PATIENTS; SAFETY; SYMPTOMS; THERAPY; WOMEN; ANIMALS; BLOOD VESSELS; BODY; CARDIOVASCULAR SYSTEM; DISEASES; FEMALES; MAMMALS; MAN; MEDICINE; ORGANS; PRIMATES; RESONANCE; UROGENITAL SYSTEM DISEASES; VERTEBRATES

Citation Formats

Scheurig-Muenkler, C, Poellinger, A, Wagner, M, Hamm, B, and Kroencke, T. J., E-mail: thomas.kroencke@charite.de. Ovarian Artery Embolization in Patients With Collateral Supply to Symptomatic Uterine Leiomyomata. United States: N. p., 2011. Web. doi:10.1007/S00270-010-9991-Y.
Scheurig-Muenkler, C, Poellinger, A, Wagner, M, Hamm, B, & Kroencke, T. J., E-mail: thomas.kroencke@charite.de. Ovarian Artery Embolization in Patients With Collateral Supply to Symptomatic Uterine Leiomyomata. United States. https://doi.org/10.1007/S00270-010-9991-Y
Scheurig-Muenkler, C, Poellinger, A, Wagner, M, Hamm, B, and Kroencke, T. J., E-mail: thomas.kroencke@charite.de. 2011. "Ovarian Artery Embolization in Patients With Collateral Supply to Symptomatic Uterine Leiomyomata". United States. https://doi.org/10.1007/S00270-010-9991-Y.
@article{osti_21608639,
title = {Ovarian Artery Embolization in Patients With Collateral Supply to Symptomatic Uterine Leiomyomata},
author = {Scheurig-Muenkler, C and Poellinger, A and Wagner, M and Hamm, B and Kroencke, T. J., E-mail: thomas.kroencke@charite.de},
abstractNote = {Purpose: To evaluate the safety and outcome of ovarian artery embolization (OAE) in patients with collateral supply to symptomatic uterine leiomyomata. Materials and Methods: Thirteen patients with relevant leiomyoma perfusion by way of enlarged ovarian arteries underwent additional OAE during the same (N = 10) or a second procedure (N = 3). Uterine artery embolization (UAE) was performed bilaterally in 10 and unilaterally in 2 patients with a single artery. One patient had no typical uterine arteries but bilaterally enlarged ovarian arteries, prompting bilateral OAE. OAE was accomplished with coil embolization in one and particle embolization in 12 patients. Symptoms before therapy and clinical outcome were assessed using a standardized questionnaire. Contrast-enhanced magnetic resonance (MR) imaging after embolization was available in 11 of 13 patients and was used to determine the percentage of fibroid infarction. Results: UAE and OAE were technically successful in all patients. One patient experienced prolonged irritation at the puncture site. Median clinical follow-up time was 16 months (range 4-37). Ten of 13 patients showed improvement or complete resolution of clinical symptoms. One patient reported only slight improvement of her symptoms. These women presented with regular menses. Two patients (15%), 47 and 48 years, both with unilateral OAE, reported permanent amenorrhea directly after embolization. Their symptoms completely resolved. Seven patients showed complete and 4 showed >90% fibroid infarction after embolization therapy. Conclusions: OAE is technically safe and effective in patients with ovarian artery collateral supply to symptomatic uterine leiomyomata. The risk of permanent amenorrhea observed in this study is similar to the reported incidence after UAE.},
doi = {10.1007/S00270-010-9991-Y},
url = {https://www.osti.gov/biblio/21608639}, journal = {Cardiovascular and Interventional Radiology},
issn = {0174-1551},
number = 6,
volume = 34,
place = {United States},
year = {Thu Dec 15 00:00:00 EST 2011},
month = {Thu Dec 15 00:00:00 EST 2011}
}