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Title: Microwave Ablation of Porcine Kidneys in vivo: Effect of two Different Ablation Modes ('Temperature Control' and 'Power Control') on Procedural Outcome

Abstract

Purpose: This study was designed to analyze the effect of two different ablation modes ('temperature control' and 'power control') of a microwave system on procedural outcome in porcine kidneys in vivo. Methods: A commercially available microwave system (Avecure Microwave Generator; MedWaves, San Diego, CA) was used. The system offers the possibility to ablate with two different ablation modes: temperature control and power control. Thirty-two microwave ablations were performed in 16 kidneys of 8 pigs. In each animal, one kidney was ablated twice by applying temperature control (ablation duration set point at 60 s, ablation temperature set point at 96 Degree-Sign C, automatic power set point; group I). The other kidney was ablated twice by applying power control (ablation duration set point at 60 s, ablation temperature set point at 96 Degree-Sign C, ablation power set point at 24 W; group II). Procedural outcome was analyzed: (1) technical success (e.g., system failures, duration of the ablation cycle), and (2) ablation geometry (e.g., long axis diameter, short axis diameter, and circularity). Results: System failures occurred in 0% in group I and 13% in group II. Duration of the ablation cycle was 60 {+-} 0 s in group I and 102 {+-} 21more » s in group II. Long axis diameter was 20.3 {+-} 4.6 mm in group I and 19.8 {+-} 3.5 mm in group II (not significant (NS)). Short axis diameter was 10.3 {+-} 2 mm in group I and 10.5 {+-} 2.4 mm in group II (NS). Circularity was 0.5 {+-} 0.1 in group I and 0.5 {+-} 0.1 in group II (NS). Conclusions: Microwave ablations performed with temperature control showed fewer system failures and were finished faster. Both ablation modes demonstrated no significant differences with respect to ablation geometry.« less

Authors:
 [1];  [2]; ; ; ;  [1]; ; ;  [2];  [3]; ;  [4]; ; ;  [1]
  1. University Hospital Heidelberg, Department of Diagnostic and Interventional Radiology (Germany)
  2. University Hospital Heidelberg, Department of General, Abdominal and Transplantation Surgery (Germany)
  3. University Hospital Heidelberg, Department of General Pathology (Germany)
  4. German Cancer Research Center, Division of Medical and Biological Informatics (Germany)
Publication Date:
OSTI Identifier:
21608540
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cardiovascular and Interventional Radiology; Journal Volume: 35; Journal Issue: 3; Other Information: DOI: 10.1007/s00270-011-0171-5; Copyright (c) 2012 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ABLATION; IN VIVO; KIDNEYS; MICROWAVE RADIATION; SWINE; TEMPERATURE CONTROL; ANIMALS; BODY; CONTROL; DOMESTIC ANIMALS; ELECTROMAGNETIC RADIATION; MAMMALS; ORGANS; RADIATIONS; VERTEBRATES

Citation Formats

Sommer, C. M., E-mail: christof.sommer@med.uni-heidelberg.de, Arnegger, F., Koch, V., Pap, B., Holzschuh, M., Bellemann, N., Gehrig, T., Senft, J., Nickel, F., Mogler, C., Zelzer, S., Meinzer, H. P., Stampfl, U., Kauczor, H. U., and Radeleff, B. A. Microwave Ablation of Porcine Kidneys in vivo: Effect of two Different Ablation Modes ('Temperature Control' and 'Power Control') on Procedural Outcome. United States: N. p., 2012. Web. doi:10.1007/S00270-011-0171-5.
Sommer, C. M., E-mail: christof.sommer@med.uni-heidelberg.de, Arnegger, F., Koch, V., Pap, B., Holzschuh, M., Bellemann, N., Gehrig, T., Senft, J., Nickel, F., Mogler, C., Zelzer, S., Meinzer, H. P., Stampfl, U., Kauczor, H. U., & Radeleff, B. A. Microwave Ablation of Porcine Kidneys in vivo: Effect of two Different Ablation Modes ('Temperature Control' and 'Power Control') on Procedural Outcome. United States. doi:10.1007/S00270-011-0171-5.
Sommer, C. M., E-mail: christof.sommer@med.uni-heidelberg.de, Arnegger, F., Koch, V., Pap, B., Holzschuh, M., Bellemann, N., Gehrig, T., Senft, J., Nickel, F., Mogler, C., Zelzer, S., Meinzer, H. P., Stampfl, U., Kauczor, H. U., and Radeleff, B. A. Fri . "Microwave Ablation of Porcine Kidneys in vivo: Effect of two Different Ablation Modes ('Temperature Control' and 'Power Control') on Procedural Outcome". United States. doi:10.1007/S00270-011-0171-5.
@article{osti_21608540,
title = {Microwave Ablation of Porcine Kidneys in vivo: Effect of two Different Ablation Modes ('Temperature Control' and 'Power Control') on Procedural Outcome},
author = {Sommer, C. M., E-mail: christof.sommer@med.uni-heidelberg.de and Arnegger, F. and Koch, V. and Pap, B. and Holzschuh, M. and Bellemann, N. and Gehrig, T. and Senft, J. and Nickel, F. and Mogler, C. and Zelzer, S. and Meinzer, H. P. and Stampfl, U. and Kauczor, H. U. and Radeleff, B. A.},
abstractNote = {Purpose: This study was designed to analyze the effect of two different ablation modes ('temperature control' and 'power control') of a microwave system on procedural outcome in porcine kidneys in vivo. Methods: A commercially available microwave system (Avecure Microwave Generator; MedWaves, San Diego, CA) was used. The system offers the possibility to ablate with two different ablation modes: temperature control and power control. Thirty-two microwave ablations were performed in 16 kidneys of 8 pigs. In each animal, one kidney was ablated twice by applying temperature control (ablation duration set point at 60 s, ablation temperature set point at 96 Degree-Sign C, automatic power set point; group I). The other kidney was ablated twice by applying power control (ablation duration set point at 60 s, ablation temperature set point at 96 Degree-Sign C, ablation power set point at 24 W; group II). Procedural outcome was analyzed: (1) technical success (e.g., system failures, duration of the ablation cycle), and (2) ablation geometry (e.g., long axis diameter, short axis diameter, and circularity). Results: System failures occurred in 0% in group I and 13% in group II. Duration of the ablation cycle was 60 {+-} 0 s in group I and 102 {+-} 21 s in group II. Long axis diameter was 20.3 {+-} 4.6 mm in group I and 19.8 {+-} 3.5 mm in group II (not significant (NS)). Short axis diameter was 10.3 {+-} 2 mm in group I and 10.5 {+-} 2.4 mm in group II (NS). Circularity was 0.5 {+-} 0.1 in group I and 0.5 {+-} 0.1 in group II (NS). Conclusions: Microwave ablations performed with temperature control showed fewer system failures and were finished faster. Both ablation modes demonstrated no significant differences with respect to ablation geometry.},
doi = {10.1007/S00270-011-0171-5},
journal = {Cardiovascular and Interventional Radiology},
number = 3,
volume = 35,
place = {United States},
year = {Fri Jun 15 00:00:00 EDT 2012},
month = {Fri Jun 15 00:00:00 EDT 2012}
}