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Title: A Dosimetric Analysis of IMRT and Multistatic Fields Techniques for Left Breast Radiotherapy

Abstract

The purpose of this study was to analyze the dosimetric difference between intensity-modulated radiation therapy (IMRT) using 3 or 5 beams and multistatic field technique (MSF) in radiotherapy of the left breast. We made comparative analysis of two kinds of radiotherapy that can achieve improved dose homogeneity. First is a MSF that uses both major and small irradiation fields at the same time. The other is IMRT using 3 or 5 beams with an inverse planning system using multiple static multileaf collimators. We made treatment plans for 16 early left breast cancer patients who were randomly selected and had undergone breast conserving surgery and radiotherapy, and analyzed them in the dosimetric aspect. For the mean values of V{sub 95} and dose homogeneity index, no statistically significant difference was observed among the three therapies. Extreme hot spots receiving >110% of prescribed dose were not found in any of the three methods. Using Tukey's test, IMRT showed a significantly larger increase in exposure dose to the ipsilateral lung and the heart than MSF in the low-dose area, but in the high-dose area, MSF showed a slight increase. To improve dose homogeneity, the application of MSF, which can be easily planned and appliedmore » more widely, is considered optimal as an alternative to IMRT for radiotherapy of early left breast cancer.« less

Authors:
 [1];  [2];  [3]; ; ; ;  [4]
  1. Department of Radiation Oncology, Soonchunhyang University Hospital, Bucheon-Si, Gyeonggi-do (Korea, Republic of)
  2. Department of Radiation Oncology, Catholic University of Korea, Seoul St. Mary's Hospital, Seoul (Korea, Republic of)
  3. Department of Preventive Medicine, Eulji University Hospital, Daejeon (Korea, Republic of)
  4. Department of Radiation Oncology, Eulji University Hospital, Daejeon (Korea, Republic of)
Publication Date:
OSTI Identifier:
21590475
Resource Type:
Journal Article
Journal Name:
Medical Dosimetry
Additional Journal Information:
Journal Volume: 36; Journal Issue: 3; Other Information: DOI: 10.1016/j.meddos.2010.05.003; PII: S0958-3947(10)00069-5; Copyright (c) 2011 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0958-3947
Country of Publication:
United States
Language:
English
Subject:
61 RADIATION PROTECTION AND DOSIMETRY; COLLIMATORS; DOSIMETRY; HEART; IRRADIATION; LUNGS; MAMMARY GLANDS; NEOPLASMS; RADIATION DOSES; RADIOTHERAPY; BODY; CARDIOVASCULAR SYSTEM; DISEASES; DOSES; GLANDS; MEDICINE; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; RESPIRATORY SYSTEM; THERAPY

Citation Formats

Moon, Seong Kwon, Kim, Yeon Sil, Kim, Soo Young, Lee, Mi Jo, Keum, Hyun Sup, Kim, Seung Jin, and Youn, Seon Min. A Dosimetric Analysis of IMRT and Multistatic Fields Techniques for Left Breast Radiotherapy. United States: N. p., 2011. Web. doi:10.1016/j.meddos.2010.05.003.
Moon, Seong Kwon, Kim, Yeon Sil, Kim, Soo Young, Lee, Mi Jo, Keum, Hyun Sup, Kim, Seung Jin, & Youn, Seon Min. A Dosimetric Analysis of IMRT and Multistatic Fields Techniques for Left Breast Radiotherapy. United States. doi:10.1016/j.meddos.2010.05.003.
Moon, Seong Kwon, Kim, Yeon Sil, Kim, Soo Young, Lee, Mi Jo, Keum, Hyun Sup, Kim, Seung Jin, and Youn, Seon Min. Sat . "A Dosimetric Analysis of IMRT and Multistatic Fields Techniques for Left Breast Radiotherapy". United States. doi:10.1016/j.meddos.2010.05.003.
@article{osti_21590475,
title = {A Dosimetric Analysis of IMRT and Multistatic Fields Techniques for Left Breast Radiotherapy},
author = {Moon, Seong Kwon and Kim, Yeon Sil and Kim, Soo Young and Lee, Mi Jo and Keum, Hyun Sup and Kim, Seung Jin and Youn, Seon Min},
abstractNote = {The purpose of this study was to analyze the dosimetric difference between intensity-modulated radiation therapy (IMRT) using 3 or 5 beams and multistatic field technique (MSF) in radiotherapy of the left breast. We made comparative analysis of two kinds of radiotherapy that can achieve improved dose homogeneity. First is a MSF that uses both major and small irradiation fields at the same time. The other is IMRT using 3 or 5 beams with an inverse planning system using multiple static multileaf collimators. We made treatment plans for 16 early left breast cancer patients who were randomly selected and had undergone breast conserving surgery and radiotherapy, and analyzed them in the dosimetric aspect. For the mean values of V{sub 95} and dose homogeneity index, no statistically significant difference was observed among the three therapies. Extreme hot spots receiving >110% of prescribed dose were not found in any of the three methods. Using Tukey's test, IMRT showed a significantly larger increase in exposure dose to the ipsilateral lung and the heart than MSF in the low-dose area, but in the high-dose area, MSF showed a slight increase. To improve dose homogeneity, the application of MSF, which can be easily planned and applied more widely, is considered optimal as an alternative to IMRT for radiotherapy of early left breast cancer.},
doi = {10.1016/j.meddos.2010.05.003},
journal = {Medical Dosimetry},
issn = {0958-3947},
number = 3,
volume = 36,
place = {United States},
year = {2011},
month = {10}
}