Functional imaging and assessment of the glucose diffusion rate in epithelial tissues in optical coherence tomography

Journal Article · Mon Jun 30 00:00:00 EDT 2008 · Quantum Electronics (Woodbury, N.Y.)

DOI:https://doi.org/10.1070/QE2008V038N06ABEH013850· OSTI ID:21519879

Larin, K V; Tuchin, V V ^[1]

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1. N. G. Chernyshevskii Saratov State University, Saratov (Russian Federation)

Functional imaging, monitoring and quantitative description of glucose diffusion in epithelial and underlying stromal tissues in vivo and controlling of the optical properties of tissues are extremely important for many biomedical applications including the development of noninvasive or minimally invasive glucose sensors as well as for therapy and diagnostics of various diseases, such as cancer, diabetic retinopathy, and glaucoma. Recent progress in the development of a noninvasive molecular diffusion biosensor based on optical coherence tomography (OCT) is described. The diffusion of glucose was studied in several epithelial tissues both in vitro and in vivo. Because OCT provides depth-resolved imaging of tissues with high in-depth resolution, the glucose diffusion is described not only as a function of time but also as a function of depth. (special issue devoted to application of laser technologies in biophotonics and biomedical studies)

• OSTI ID: 21519879
• Journal Information: Quantum Electronics (Woodbury, N.Y.), Vol. 38, Issue 6; Other Information: DOI: 10.1070/QE2008v038n06ABEH013850; ISSN 1063-7818
• Country of Publication: United States
• Language: English

Related Subjects

60 APPLIED LIFE SCIENCES
ANIMAL TISSUES
DIFFUSION
GLUCOSE
IN VITRO
IN VIVO
LASERS
NEOPLASMS
OPTICAL PROPERTIES
RESOLUTION
SENSORS
THERAPY
TIME DEPENDENCE
TOMOGRAPHY
ALDEHYDES
BODY
CARBOHYDRATES
DIAGNOSTIC TECHNIQUES
DISEASES
HEXOSES
MEDICINE
MONOSACCHARIDES
ORGANIC COMPOUNDS
PHYSICAL PROPERTIES
SACCHARIDES