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Title: Lasers As Particle Accelerators In Medicine: From Laser-Driven Protons To Imaging With Thomson Sources

Abstract

We report our recent progress using a high-power, picosecond CO{sub 2} laser for Thomson scattering and ion acceleration experiments. These experiments capitalize on certain advantages of long-wavelength CO{sub 2} lasers, such as their high number of photons per energy unit and beneficial wavelength- scaling of the electrons' ponderomotive energy and critical plasma frequency. High X-ray fluxes produced in the interactions of the counter-propagating laser- and electron-beams for obtaining single-shot, high-contrast images of biological objects. The laser, focused on a hydrogen jet, generated a monoenergetic proton beam via the radiation-pressure mechanism. The energy of protons produced by this method scales linearly with the laser's intensity. We present a plan for scaling the process into the range of 100-MeV proton energy via upgrading the CO{sub 2} laser. This development will enable an advance to the laser-driven proton cancer therapy.

Authors:
; ; ;  [1]; ; ;  [2];  [3]; ;  [4]; ; ;  [5]; ;  [6];
  1. Brookhaven National Laboratory, Accelerator Test Facility, Upton NY 11973 (United States)
  2. Blackett Laboratory, Imperial College London, SW7 2BW (United Kingdom)
  3. State University of New York, Stony Brook, NY 11794 (United States)
  4. University of California, Los Angeles, Department of Physics and Astronomy, Los Angeles, CA 90095 (United States)
  5. Struttura Dipartimentale di Matematica e Fisica, Univ. di Sassari and INFN, Sezione di Cagliari 07100 (Italy)
  6. Dipartimento di Fisica 'E. Fermi', Universita di Pisa, Largo B. Pontecorvo 3, 56127 Pisa (Italy) and INFN, Sezione di Pisa 56127 (Italy)
Publication Date:
OSTI Identifier:
21513383
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 1336; Journal Issue: 1; Conference: CAARI 2010: 21. International Conference on the Application of Accelerators in Research and Industry, Fort Worth, TX (United States), 8-13 Aug 2010; Other Information: DOI: 10.1063/1.3586126; (c) 2011 American Institute of Physics
Country of Publication:
United States
Language:
English
Subject:
43 PARTICLE ACCELERATORS; ACCELERATION; ACCELERATORS; CARBON DIOXIDE LASERS; ELECTRON BEAMS; ELECTRONS; HYDROGEN; IONS; LANGMUIR FREQUENCY; MEV RANGE 100-1000; NEOPLASMS; PHOTONS; PONDEROMOTIVE FORCE; PROTON BEAMS; PROTONS; RADIATION PRESSURE; RADIOTHERAPY; SCALING; THOMSON SCATTERING; WAVELENGTHS; X RADIATION; BARYONS; BEAMS; BOSONS; CHARGED PARTICLES; DISEASES; ELECTROMAGNETIC RADIATION; ELEMENTARY PARTICLES; ELEMENTS; ENERGY RANGE; FERMIONS; GAS LASERS; HADRONS; INELASTIC SCATTERING; IONIZING RADIATIONS; LASERS; LEPTON BEAMS; LEPTONS; MASSLESS PARTICLES; MEDICINE; MEV RANGE; NONMETALS; NUCLEAR MEDICINE; NUCLEON BEAMS; NUCLEONS; PARTICLE BEAMS; RADIATIONS; RADIOLOGY; SCATTERING; THERAPY

Citation Formats

Pogorelsky, I. V., Babzien, M., Polyanskiy, M. N., Yakimenko, V., Dover, N. P., Palmer, C. A. J., Najmudin, Z., Shkolnikov, P., Williams, O., Rosenzweig, J., Oliva, P., Carpinelli, M., Golosio, B., Delogu, P., Stefanini, A., and Endrizzi, M.. Lasers As Particle Accelerators In Medicine: From Laser-Driven Protons To Imaging With Thomson Sources. United States: N. p., 2011. Web. doi:10.1063/1.3586126.
Pogorelsky, I. V., Babzien, M., Polyanskiy, M. N., Yakimenko, V., Dover, N. P., Palmer, C. A. J., Najmudin, Z., Shkolnikov, P., Williams, O., Rosenzweig, J., Oliva, P., Carpinelli, M., Golosio, B., Delogu, P., Stefanini, A., & Endrizzi, M.. Lasers As Particle Accelerators In Medicine: From Laser-Driven Protons To Imaging With Thomson Sources. United States. doi:10.1063/1.3586126.
Pogorelsky, I. V., Babzien, M., Polyanskiy, M. N., Yakimenko, V., Dover, N. P., Palmer, C. A. J., Najmudin, Z., Shkolnikov, P., Williams, O., Rosenzweig, J., Oliva, P., Carpinelli, M., Golosio, B., Delogu, P., Stefanini, A., and Endrizzi, M.. Wed . "Lasers As Particle Accelerators In Medicine: From Laser-Driven Protons To Imaging With Thomson Sources". United States. doi:10.1063/1.3586126.
@article{osti_21513383,
title = {Lasers As Particle Accelerators In Medicine: From Laser-Driven Protons To Imaging With Thomson Sources},
author = {Pogorelsky, I. V. and Babzien, M. and Polyanskiy, M. N. and Yakimenko, V. and Dover, N. P. and Palmer, C. A. J. and Najmudin, Z. and Shkolnikov, P. and Williams, O. and Rosenzweig, J. and Oliva, P. and Carpinelli, M. and Golosio, B. and Delogu, P. and Stefanini, A. and Endrizzi, M.},
abstractNote = {We report our recent progress using a high-power, picosecond CO{sub 2} laser for Thomson scattering and ion acceleration experiments. These experiments capitalize on certain advantages of long-wavelength CO{sub 2} lasers, such as their high number of photons per energy unit and beneficial wavelength- scaling of the electrons' ponderomotive energy and critical plasma frequency. High X-ray fluxes produced in the interactions of the counter-propagating laser- and electron-beams for obtaining single-shot, high-contrast images of biological objects. The laser, focused on a hydrogen jet, generated a monoenergetic proton beam via the radiation-pressure mechanism. The energy of protons produced by this method scales linearly with the laser's intensity. We present a plan for scaling the process into the range of 100-MeV proton energy via upgrading the CO{sub 2} laser. This development will enable an advance to the laser-driven proton cancer therapy.},
doi = {10.1063/1.3586126},
journal = {AIP Conference Proceedings},
number = 1,
volume = 1336,
place = {United States},
year = {Wed Jun 01 00:00:00 EDT 2011},
month = {Wed Jun 01 00:00:00 EDT 2011}
}
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