Laser analysis of the {sup 13}C/{sup 12}C isotope ratio in CO{sub 2} in exhaled air
- A.M. Prokhorov General Physics Institute, Russian Academy of Sciences, Moscow (Russian Federation)
Tunable diode lasers (TDLs) are applied to the diagnostics of gastroenterological diseases using respiratory tests and preparations enriched with the stable {sup 13}C isotope. This method of the analysis of the {sup 13}C/{sup 12}C isotope ratio in CO{sub 2} in exhaled air is based on the selective measurement of the resonance absorption at the vibrational - rotational structure of {sup 12}CO{sub 2} and {sup 13}CO{sub 2}. The CO{sub 2} transmission spectra in the region of 4.35 {mu}m were measured with a PbEuSe double-heterostructure TDL. The accuracy of carbon isotope ratio measurements in CO{sub 2} of exhaled air performed with the TDL was {approx}0.5%. The data of clinical tests of the developed laser-based analyser are presented. (laser biology and medicine)
- OSTI ID:
- 21459979
- Journal Information:
- Quantum Electronics (Woodbury, N.Y.), Vol. 32, Issue 11; Other Information: DOI: 10.1070/QE2002v032n11ABEH002332; ISSN 1063-7818
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
ACCURACY
AIR
CARBON 12
CARBON 13
CARBON DIOXIDE
ISOTOPE RATIO
LASERS
MEDICINE
RESONANCE ABSORPTION
TRANSMISSION
ABSORPTION
CARBON COMPOUNDS
CARBON ISOTOPES
CARBON OXIDES
CHALCOGENIDES
DIMENSIONLESS NUMBERS
EVEN-EVEN NUCLEI
EVEN-ODD NUCLEI
FLUIDS
GASES
ISOTOPES
LIGHT NUCLEI
NUCLEI
OXIDES
OXYGEN COMPOUNDS
SORPTION
STABLE ISOTOPES