Direct opto-acoustic in vitro measurement of the spatial distribution of laser radiation in biological media

Journal Article · Sun Dec 31 00:00:00 EST 2006 · Quantum Electronics (Woodbury, N.Y.)

DOI:https://doi.org/10.1070/QE2006V036N12ABEH013261· OSTI ID:21456921

Pelivanov, Ivan M; Belov, Sergej A; Solomatin, Vladimir S; Khokhlova, Tanya D; Karabutov, Aleksander A ^[1]

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1. International Laser Center, M. V. Lomonosov Moscow State University, Moscow (Russian Federation)

The problem of opto-acoustic (AO) diagnostics of light scattering and absorption in biological media is considered. The objects under study were milk, bovine and porcine liver, and bovine muscle tissue. The forward and backward schemes for recording acoustic signals were used in experiments. The spatial distribution of the light intensity was measured for each biological medium from the temporal profile of the excited OA pulse and the absorption coefficient and reduced scattering coefficient were determined. Opto-acoustic signals were excited by a 1064-nm pulsed Nd:YAG laser and a tunable Ti:sapphire laser at 779 nm. It is shown that the proposed method can be used for obtaining a priori information on a biological medium in problems of optical and AO tomography. (special issue devoted to multiple radiation scattering in random media)

• OSTI ID: 21456921
• Journal Information: Quantum Electronics (Woodbury, N.Y.), Vol. 36, Issue 12; Other Information: DOI: 10.1070/QE2006v036n12ABEH013261; ISSN 1063-7818
• Country of Publication: United States
• Language: English

Related Subjects

60 APPLIED LIFE SCIENCES
ACOUSTIC MEASUREMENTS
CATTLE
IN VITRO
LASER RADIATION
LIGHT SCATTERING
LIVER
MILK
MUSCLES
NEODYMIUM LASERS
PHOTOACOUSTIC SPECTROSCOPY
PULSES
SAPPHIRE
SIGNALS
SPATIAL DISTRIBUTION
TOMOGRAPHY
VISIBLE RADIATION
ANIMALS
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
CORUNDUM
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISTRIBUTION
DOMESTIC ANIMALS
ELECTROMAGNETIC RADIATION
FOOD
GLANDS
LASERS
MAMMALS
MATERIALS
MINERALS
ORGANS
OXIDE MINERALS
RADIATIONS
RUMINANTS
SCATTERING
SOLID STATE LASERS
SPECTROSCOPY
VERTEBRATES