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Title: Interplay of noncoding RNAs, mRNAs, and proteins during the growth of eukaryotic cells

Journal Article · · Journal of Experimental and Theoretical Physics
 [1]
  1. Chalmers University of Technology, Department of Applied Physics (Sweden)

Numerous biological functions of noncoding RNAs (ncRNAs) in eukaryotic cells are based primarily on their ability to pair with target mRNAs and then either to prevent translation or to result in rapid degradation of the mRNA-ncRNA complex. Using a general model describing this scenario, we show that ncRNAs may help to maintain constant mRNA and protein concentrations during the growth of cells. The possibility of observation of this effect on the global scale is briefly discussed.

OSTI ID:
21451197
Journal Information:
Journal of Experimental and Theoretical Physics, Vol. 111, Issue 4; Other Information: DOI: 10.1134/S1063776110100213; Copyright (c) 2010 Pleiades Publishing, Ltd.; ISSN 1063-7761
Country of Publication:
United States
Language:
English