A Comparison of Transjugular and Plugged-Percutaneous Liver Biopsy in Patients with Contraindications to Ordinary Percutaneous Liver Biopsy and an 'In-House' Protocol for Selecting the Procedure of Choice
- Hasharon Hospital, Vascular and Interventional Units, Department of Diagnostic Radiology (Israel)
- Beilinson Hospital, Liver Institute (Israel)
- Beilinson Hospital, Vascular and Interventional Units, Department of Diagnostic Radiology (Israel)
- Hasharon Hospital, Gastroenterology Unit (Israel)
- Institute of Gastroenterology, Rabin Medical Center, Unit of Liver Transplantation (Israel)
- Schneider Children Medical Center, Department of Pediatric Cardiology (Israel)
- Beilinson Hospital, Department of Internal Medicine (Israel)
The purpose of this study was to evaluate the effectiveness and safety of transjugular liver biopsy (TJLB) and plugged-percutaneous liver biopsy (PB) in consecutive patients with severe liver disease associated with impaired coagulation, ascites, or both and to verify the in-house protocol used to select the appropriate procedure. In 2000-2006, 329 patients (208 male [62.8%] and 121 female [37.2%]), aged 1 month to 81 years (mean, 46.8 years), underwent 150 TJLBs (39.1%) or 233 PBs (60.9%) procedures at a major tertiary center, as determined by an in-house protocol. The groups were compared for specimen characteristics, technical success, and complications. Technical success rates were 97.4% for TJLB (146/150) and 99.1% for PB (231/233). TJLB was associated with a lower average core length (1.29 vs. 1.43 cm) and lower average number of specimens obtained (2.44 vs. 2.8), but both methods yielded sufficient tissue for a definitive diagnosis. There were no major complications in either group. TJLB and PB can be safely and effectively performed for the diagnosis of hepatic disease in patients with contraindications for standard percutaneous liver biopsy. When both are technically available, we suggest PB as the procedure of choice, especially in transplanted livers.
- OSTI ID:
- 21428989
- Journal Information:
- Cardiovascular and Interventional Radiology, Vol. 33, Issue 3; Other Information: DOI: 10.1007/s00270-009-9743-z; Copyright (c) 2010 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); ISSN 0174-1551
- Country of Publication:
- United States
- Language:
- English
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