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Title: Pilot Study to Confirm that Fat and Liver can be Distinguished by Spectroscopic Tissue Response on a Medipix-All-Resolution System-CT (MARS-CT)

Abstract

NAFLD, liver component of the 'metabolic' syndrome, has become the most common liver disease in western nations. Non-invasive imaging techniques exist, but have limitations, especially in detection and quantification of mild to moderate fatty liver. In this pilot study, we produced attenuation curves from biomedical-quality projection images of liver and fat using the MARS spectroscopic-CT scanner. Difficulties obtaining attenuation spectra after reconstruction demonstrated that standard reconstruction programs do not preserve spectral information.

Authors:
; ;  [1]; ;  [2];  [3];  [4];  [2];  [1]
  1. Department of Radiology, University of Otago, Christchurch (New Zealand)
  2. Physics and Astronomy, University of Canterbury Christchurch (New Zealand)
  3. Department of Medical Physics, Canterbury District Health Board, Christchurch (New Zealand)
  4. Christchurch Cardioendocrine Research Group, University of Otago, Christchurch (New Zealand)
Publication Date:
OSTI Identifier:
21344288
Resource Type:
Journal Article
Journal Name:
AIP Conference Proceedings
Additional Journal Information:
Journal Volume: 1151; Journal Issue: 1; Conference: AMN-4: International conference on advanced materials and nanotechnology, Dunedin (New Zealand), 8-12 Feb 2009; Other Information: DOI: 10.1063/1.3203212; (c) 2009 American Institute of Physics; Journal ID: ISSN 0094-243X
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ATTENUATION; COMPUTERIZED TOMOGRAPHY; FATS; IMAGES; LIVER; METABOLIC DISEASES; NMR IMAGING; NMR SPECTRA; RESOLUTION; ULTRASONOGRAPHY; BODY; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; GLANDS; ORGANS; SPECTRA; TOMOGRAPHY

Citation Formats

Berg, Kyra B, Anderson, Nigel G, Butler, Alexandra P, Carr, James M, Clark, Michael J, Cook, Nick J, Scott, Nicola J, Butler, Philip H, European Organization for Nuclear Research, Geneva, Butler, Anthony P, Physics and Astronomy, University of Canterbury Christchurch, European Organization for Nuclear Research, Geneva, and Electrical and Computer Engineering, University of Canterbury, Christchurch. Pilot Study to Confirm that Fat and Liver can be Distinguished by Spectroscopic Tissue Response on a Medipix-All-Resolution System-CT (MARS-CT). United States: N. p., 2009. Web. doi:10.1063/1.3203212.
Berg, Kyra B, Anderson, Nigel G, Butler, Alexandra P, Carr, James M, Clark, Michael J, Cook, Nick J, Scott, Nicola J, Butler, Philip H, European Organization for Nuclear Research, Geneva, Butler, Anthony P, Physics and Astronomy, University of Canterbury Christchurch, European Organization for Nuclear Research, Geneva, & Electrical and Computer Engineering, University of Canterbury, Christchurch. Pilot Study to Confirm that Fat and Liver can be Distinguished by Spectroscopic Tissue Response on a Medipix-All-Resolution System-CT (MARS-CT). United States. https://doi.org/10.1063/1.3203212
Berg, Kyra B, Anderson, Nigel G, Butler, Alexandra P, Carr, James M, Clark, Michael J, Cook, Nick J, Scott, Nicola J, Butler, Philip H, European Organization for Nuclear Research, Geneva, Butler, Anthony P, Physics and Astronomy, University of Canterbury Christchurch, European Organization for Nuclear Research, Geneva, and Electrical and Computer Engineering, University of Canterbury, Christchurch. 2009. "Pilot Study to Confirm that Fat and Liver can be Distinguished by Spectroscopic Tissue Response on a Medipix-All-Resolution System-CT (MARS-CT)". United States. https://doi.org/10.1063/1.3203212.
@article{osti_21344288,
title = {Pilot Study to Confirm that Fat and Liver can be Distinguished by Spectroscopic Tissue Response on a Medipix-All-Resolution System-CT (MARS-CT)},
author = {Berg, Kyra B and Anderson, Nigel G and Butler, Alexandra P and Carr, James M and Clark, Michael J and Cook, Nick J and Scott, Nicola J and Butler, Philip H and European Organization for Nuclear Research, Geneva and Butler, Anthony P and Physics and Astronomy, University of Canterbury Christchurch and European Organization for Nuclear Research, Geneva and Electrical and Computer Engineering, University of Canterbury, Christchurch},
abstractNote = {NAFLD, liver component of the 'metabolic' syndrome, has become the most common liver disease in western nations. Non-invasive imaging techniques exist, but have limitations, especially in detection and quantification of mild to moderate fatty liver. In this pilot study, we produced attenuation curves from biomedical-quality projection images of liver and fat using the MARS spectroscopic-CT scanner. Difficulties obtaining attenuation spectra after reconstruction demonstrated that standard reconstruction programs do not preserve spectral information.},
doi = {10.1063/1.3203212},
url = {https://www.osti.gov/biblio/21344288}, journal = {AIP Conference Proceedings},
issn = {0094-243X},
number = 1,
volume = 1151,
place = {United States},
year = {Thu Jul 23 00:00:00 EDT 2009},
month = {Thu Jul 23 00:00:00 EDT 2009}
}